vascular surgery; perioperative medicine; direct oral anticoagulant
Abstract :
[en] Since their first approval in 2010, direct oral anticoagulants (DOACs) have become attractive for anticoagulant treatment. DOACs are indicated for the prevention and treatment of several cardiovascular conditions and have now emerged as leading therapeutic options. Every year, large number of patients receiving DOACs routinely are scheduled for invasive surgical procedures and need specific perioperative management. Moreover, recently published trials have provided arguments for a larger future use of DOACs, including during the postoperative period after vascular surgery and for high-risk cardiovascular patients. In this communication, we discuss the perioperative management of DOACs for patients undergoing vascular surgery.
Disciplines :
Anesthesia & intensive care
Author, co-author :
Houben, Alan ; Centre Hospitalier Universitaire de Liège - CHU > > Service d'anesthésie - réanimation
Bonhomme, Vincent ; Centre Hospitalier Universitaire de Liège - CHU > > Service d'anesthésie - réanimation
Senard, Marc ; Centre Hospitalier Universitaire de Liège - CHU > > Service d'anesthésie - réanimation
Language :
English
Title :
Clinical Use of Direct Oral Anticoagulants and Reversal: Consideration for Vascular Surgeons
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Bibliography
Chen A. Stecker E. Warden B.A. Direct Oral Anticoagulant Use: A Practical Guide to Common Clinical Challenges J. Am. Heart Assoc. 2020 9 e017559 10.1161/JAHA.120.017559 32538234
Eikelboom J.W. Connolly S.J. Bosch J. Dagenais G.R. Hart R.G. Shestakovska O. Diaz R. Alings M. Lonn E.M. Anand S.S. et al. Rivaroxaban with or without Aspirin in Stable Cardiovascular Disease N. Engl. J. Med. 2017 377 1319 1330 10.1056/NEJMoa1709118 28844192
Devereaux P.J. Duceppe E. Guyatt G. Tandon V. Rodseth R. Biccard B.M. Xavier D. Szczeklik W. Meyhoff C.S. Vincent J. et al. Dabigatran in patients with myocardial injury after non-cardiac surgery (MANAGE): An international, randomised, placebo-controlled trial Lancet 2018 391 2325 2334 10.1016/S0140-6736(18)30832-8 29900874
Steffel J. Verhamme P. Potpara T.S. Albaladejo P. Antz M. Desteghe L. Haeusler K.G. Oldgren J. Reinecke H. Roldan-Schilling V. et al. The 2018 European Heart Rhythm Association Practical Guide on the use of non-vitamin K antagonist oral anticoagulants in patients with atrial fibrillation Eur. Heart J. 2018 39 1330 1393 10.1093/eurheartj/ehy136
Aursulesei V. Costache I.I. Anticoagulation in chronic kidney disease: From guidelines to clinical practice Clin. Cardiol. 2019 42 774 782 10.1002/clc.23196
Lopes R.D. Heizer G. Aronson R. Vora A.N. Massaro T. Mehran R. Goodman S.G. Windecker S. Darius H. Li J. et al. Antithrombotic Therapy after Acute Coronary Syndrome or PCI in Atrial Fibrillation N. Engl. J. Med. 2019 380 1509 1524 10.1056/NEJMoa1817083
Vranckx P. Valgimigli M. Eckardt L. Tijssen J. Lewalter T. Gargiulo G. Batushkin V. Campo G. Lysak Z. Vakaliuk I. et al. Edoxaban-based versus vitamin K antagonist-based antithrombotic regimen after successful coronary stenting in patients with atrial fibrillation (ENTRUST-AF PCI): A randomised, open-label, phase 3b trial Lancet 2019 394 1335 1343 10.1016/S0140-6736(19)31872-0
Bonaca M.P. Bauersachs R.M. Anand S.S. Debus E.S. Nehler M.R. Patel M.R. Fanelli F. Capell W.H. Diao L. Jaeger N. et al. Rivaroxaban in Peripheral Artery Disease after Revascularization N. Engl. J. Med. 2020 382 1994 2004 10.1056/NEJMoa2000052 32222135
Godier A. Dincq A.S. Martin A.C. Radu A. Leblanc I. Antona M. Vasse M. Golmard J.L. Mullier F. Gouin-Thibault I. Predictors of pre-procedural concentrations of direct oral anticoagulants: A prospective multicentre study Eur. Heart J. 2017 38 2431 2439 10.1093/eurheartj/ehx403 28821169
Pernod G. Albaladejo P. Godier A. Samama C.M. Susen S. Gruel Y. Blais N. Fontana P. Cohen A. Llau J.V. et al. Management of major bleeding complications and emergency surgery in patients on long-term treatment with direct oral anticoagulants, thrombin or factor-Xa inhibitors: Proposals of the working group on perioperative haemostasis (GIHP) Arch. Cardiovasc. Dis. 2013 106 382 393 10.1016/j.acvd.2013.04.009 23810130
Albaladejo P. Bonhomme F. Blais N. Collet J.P. Faraoni D. Fontana P. Godier A. Llau J. Longrois D. Marret E. et al. Management of direct oral anticoagulants in patients undergoing elective surgeries and invasive procedures: Updated guidelines from the French Working Group on Perioperative Hemostasis (GIHP)-September 2015 Anaesth. Crit. Care Pain Med. 2017 36 73 76 10.1016/j.accpm.2016.09.002 27659969
Douketis J.D. Spyropoulos A.C. Duncan J. Carrier M. Le Gal G. Tafur A.J. Vanassche T. Verhamme P. Shivakumar S. Gross P.L. et al. Perioperative Management of Patients with Atrial Fibrillation Receiving a Direct Oral Anticoagulant JAMA Intern. Med. 2019 179 1469 1478 10.1001/jamainternmed.2019.2431
Pollack C.V. Jr. Reilly P.A. Eikelboom J. Glund S. Verhamme P. Bernstein R.A. Dubiel R. Huisman M.V. Hylek E.M. Kamphuisen P.W. et al. Idarucizumab for Dabigatran Reversal N. Engl. J. Med. 2015 373 511 520 10.1056/NEJMoa1502000 26095746
Connolly S.J. Crowther M. Eikelboom J.W. Gibson C.M. Curnutte J.T. Lawrence J.H. Yue P. Bronson M.D. Lu G. Conley P.B. et al. Full Study Report of Andexanet Alfa for Bleeding Associated with Factor Xa Inhibitors N. Engl. J. Med. 2019 380 1326 1335 10.1056/NEJMoa1814051
Boissier E. Senage T. Babuty A. Gouin-Thibault I. Rozec B. Roussel J.C. Sigaud M. Ternisien C. Trossaert M. Fouassier M. et al. Heparin Anti-Xa Activity, a Readily Available Unique Test to Quantify Apixaban, Rivaroxaban, Fondaparinux, and Danaparoid Levels Anesth. Analg. 2021 132 707 716 10.1213/ANE.0000000000005114 32833716
Erdoes G. Koster A. Ortmann E. Meesters M.I. Bolliger D. Baryshnikova E. Martinez Lopez De Arroyabe B. Ahmed A. Lance M.D. Ranucci M. et al. A European consensus statement on the use of four-factor prothrombin complex concentrate for cardiac and non-cardiac surgical patients Anaesthesia 2021 76 381 392 10.1111/anae.15181
Lewis J. Iqbal O. Jeske W. Hoppensteadt D. Siddiqui F. Fareed J. Differential Neutralization of Unfractionated Heparin and Enoxaparin by Andexanet Alfa Clin. Appl. Thromb. Hemost. 2022 28 10760296221099934 10.1177/10760296221099934
Erdoes G. Birschmann I. Nagler M. Koster A. Andexanet Alfa-Induced Heparin Resistance: When Anticoagulation Really Remains Reversed J. Cardiothorac. Vasc. Anesth. 2021 35 908 909 10.1053/j.jvca.2020.11.052
Steffel J. Collins R. Antz M. Cornu P. Desteghe L. Haeusler K.G. Oldgren J. Reinecke H. Roldan-Schilling V. Rowell N. et al. 2021 European Heart Rhythm Association Practical Guide on the Use of Non-Vitamin K Antagonist Oral Anticoagulants in Patients with Atrial Fibrillation Europace 2021 23 1612 1676 10.1093/europace/euab065 33895845
Kietaibl S. Ferrandis R. Godier A. Llau J. Lobo C. Macfarlane A.J. Schlimp C. Vandermeulen E. Volk T. von Heymann C. et al. Regional anaesthesia in patients on antithrombotic drugs: Joint ESAIC/ESRA guidelines Eur. J. Anaesthesiol. 2022 39 100 132 10.1097/EJA.0000000000001600 34980845
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