Is transcranial direct current stimulation (tDCS) effective to improve cognition and functionality after severe traumatic brain injury? A perspective article and hypothesis.
Cordeiro, Bárbara Naeme de Lima; Kuster, Elizângela; Thibaut, Auroreet al.
2023 • In Frontiers in Human Neuroscience, 17, p. 1162854
cognition; functionality; neuromodulation; rehabilitation; transcranial direct current stimulation; traumatic brain injury; Neuropsychology and Physiological Psychology; Neurology; Psychiatry and Mental Health; Biological Psychiatry; Behavioral Neuroscience
Abstract :
[en] Severe traumatic brain injury (sTBI) is an important cause of disability and mortality and affects people of all ages. Current scientific evidence indicates that motor dysfunction and cognitive impairment are the main limiting factors in patients with sTBI. Transcranial direct current stimulation (tDCS) seems to be a good therapeutic option, but when it comes to patients with sTBI, the results are inconclusive, and some protocols have not yet been tested. In addition, there is still a lack of information on tDCS-related physiological mechanisms, especially during the acute phase. In the present study, based on current evidence on tDCS mechanisms of action, we hypothesized that performing tDCS sessions in individuals with sTBI, especially in the acute and subacute phases, together with conventional therapy sessions, could improve cognition and motor function in this population. This hypothesis presents a new possibility for treating sTBI, seeking to elucidate the extent to which early tDCS may affect long-term clinical outcomes.
Disciplines :
Neurosciences & behavior
Author, co-author :
Cordeiro, Bárbara Naeme de Lima; Department of Physiological Sciences, Universidade Federal do Espírito Santo, Vitória, Brazil
Kuster, Elizângela; Center of Health Sciences, Discipline of Physical Therapy, Universidade Federal do Espírito Santo, Vitória, Brazil
Thibaut, Aurore ; Université de Liège - ULiège > GIGA > GIGA Consciousness - Coma Science Group
Rodrigues Nascimento, Lucas; Center of Health Sciences, Discipline of Physical Therapy, Universidade Federal do Espírito Santo, Vitória, Brazil ; Laboratory of Neurorehabilitation and Neuromodulation, Department of Physiological Sciences, Universidade Federal do Espírito Santo, Vitória, Brazil
Gonçalves, Jessica Vaz; Department of Physiological Sciences, Universidade Federal do Espírito Santo, Vitória, Brazil
Arêas, Guilherme Peixoto Tinoco; Physiology Science Laboratory, Universidade Federal do Amazonas, Manaus, Brazil
Paiva, Wellingson Silva; Division of Neurosurgery, Hospital das Clinicas HCFMUSP, São Paulo, Brazil
Arêas, Fernando Zanela da Silva; Center of Health Sciences, Discipline of Physical Therapy, Universidade Federal do Espírito Santo, Vitória, Brazil ; Laboratory of Neurorehabilitation and Neuromodulation, Department of Physiological Sciences, Universidade Federal do Espírito Santo, Vitória, Brazil
Language :
English
Title :
Is transcranial direct current stimulation (tDCS) effective to improve cognition and functionality after severe traumatic brain injury? A perspective article and hypothesis.
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