Shaping the cerebral cortex by cellular crosstalk.

Cell Communication; Cognition; Cerebral Cortex; Neurogenesis; Biochemistry, Genetics and Molecular Biology (all); General Biochemistry, Genetics and Molecular Biology

Abstract :

[en] The cerebral cortex is the brain's outermost layer. It is responsible for processing motor and sensory information that support high-level cognitive abilities and shape personality. Its development and functional organization strongly rely on cell communication that is established via an intricate system of diffusible signals and physical contacts during development. Interfering with this cellular crosstalk can cause neurodevelopmental disorders. Here, we review how crosstalk between migrating cells and their environment influences cerebral cortex development, ranging from neurogenesis to synaptogenesis and assembly of cortical circuits.

Disciplines :

Neurology

Author, co-author :

Stoufflet, Julie ; Université de Liège - ULiège > Département des sciences biomédicales et précliniques

Tielens, Sylvia ; Université de Liège - ULiège > Département des sciences biomédicales et précliniques

Nguyen, Laurent ; Université de Liège - ULiège > Département des sciences biomédicales et précliniques

Language :

English

Title :

Shaping the cerebral cortex by cellular crosstalk.

Publication date :

22 June 2023

Journal title :

Cell

ISSN :

0092-8674

eISSN :

1097-4172

Publisher :

Elsevier B.V., United States

Volume :

186

Issue :

Pages :

2733 - 2747

Peer reviewed :

Peer Reviewed verified by ORBi

Additional URL :

https://api.elsevier.com/content/article/PII:S0092867423005925?httpAccept=text/xml

Funding text :

We thank Dr. I. Caillé, Dr. A. Bonafina, and Dr. E. Epifanova for providing comments on the manuscript. The work performed in the Nguyen laboratory is supported by ULiège (Crédit Classique), the F.R.S.-F.N.R.S. (PDR T.0185.20 ; EOS 0019118F-RG36 ); WELBIO ( CR-2022A-12 ); the Fonds Leon Fredericq ; the Fondation Simone et Pierre Clerdent ; the ERANET Neuron (STEM-MCD and NeuroTalk); and the Win2Wal (ChipOmics; # 2010126 ). J.S. and L.N. are, respectively, postdoctoral researcher and research director of the F.R.S-F.N.R.S., and S.T. is a postdoctoral researcher supported by Win2Wal (ChipOmics; # 2010126 ).

Data Set :

https://doi.org/10.1016/j.cell.2023.05.040

Available on ORBi :

since 03 July 2023

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