COVID-19; GERIA-COVID; GNRI; Malnutrition; Mortality; Oldest-old; Aged; Aged, 80 and over; Female; Geriatric Assessment; Humans; Inpatients; Male; Nutrition Assessment; Nutritional Status; Risk Factors; Malnutrition/complications; Malnutrition/diagnosis; Biochemistry, Genetics and Molecular Biology (all); Obstetrics and Gynecology; General Biochemistry, Genetics and Molecular Biology
Abstract :
[en] We assessed the impact of malnutrition on 14-day, 28-day, and 3-month mortality risk in oldest-old inpatients aged ≥80 years with COVID-19 in the hospital-based GERIA-COVID cohort. Malnutrition was assessed on hospital admission using the Geriatric Nutritional Risk Index (GNRI). Potential confounders were age, sex, functional abilities, number of acute health issues, CRP level, hypertension, cardiomyopathy, malignancies, use of antibiotics, and respiratory treatments. Seventy-eight participants (88.9 ± 4.3 years old, 55% women) were included. Of these, 82.1% had survived at day 14, 78.2% at day 28, and 70.5% after 3 months. No association between malnutrition according to the GNRI and 14-day (P = 0.324), 28-day (P = 0.166), or 3-month mortality (P = 0.109) was found. Thus, malnutrition according to the GNRI was not associated with mortality within the first 3 months of diagnosis of COVID-19 among oldest-old inpatients.
Disciplines :
Geriatrics
Author, co-author :
Sanchez Rodriguez, Maria Dolores Carmen ; Université de Liège - ULiège > Département des sciences de la santé publique > Santé publique, Epidémiologie et Economie de la santé
Sacco, Guillaume ; Department of Geriatric Medicine and Memory Clinic, Research Center on Autonomy and Longevity, University Hospital, Angers, France
Gautier, Jennifer ; Department of Geriatric Medicine and Memory Clinic, Research Center on Autonomy and Longevity, University Hospital, Angers, France
Brière, Olivier ; Department of Geriatric Medicine and Memory Clinic, Research Center on Autonomy and Longevity, University Hospital, Angers, France
Annweiler, Cédric ; Department of Geriatric Medicine and Memory Clinic, Research Center on Autonomy and Longevity, University Hospital, Angers, France, University of Angers,UPRES EA 4638, Angers, France, Gérontopôle Autonomie Longévité des Pays de la Loire, F-44000 Nantes, France, Robarts Research Institute, Department of Medical Biophysics, Schulich School of Medicine and Dentistry, The University of Western Ontario, London, ON N6A 5K8, Canada
GERIA-COVID study group
Language :
English
Title :
Effects of malnutrition on mortality in oldest-old inpatients with COVID-19 in the GERIA-COVID cohort.
The authors wish to thank the GERIA-COVID study group. GERIA-COVID study group: Cédric Annweiler, Marine Asfar, Mélinda Beaudenon, Jean Barré, Antoine Brangier, Mathieu Corvaisier, Guillaume Duval, Jennifer Gautier, Mialy Guenet, Jocelyne Loison, Frédéric Noublanche, Marie Otekpo, Hélène Rivière, Guillaume Sacco, Romain Simon. Affiliation: Department of Geriatric Medicine, University Hospital, Angers, France. The authors have listed everyone who contributed significantly to the work in the Acknowledgments section. Permission was obtained from all persons named in the Acknowledgments section. There was no compensation for this contribution. The authors gratefully acknowledge Elaine Lilly PhD for language revisions and unfailing support.
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