The role of comprehensive two-dimensional gas chromatography in mineral oil determination.

Comprehensive two-dimensional gas chromatography (GC × GC); Food; Hyphenated chromatographic techniques; Mineral oil aromatic hydrocarbons (MOAH); Mineral oil saturated hydrocarbons (MOSH); Chromatographic techniques; Comprehensive two-dimensional gas chromatography; GC×GC; Hyphenated chromatographic technique; Liquid chromatography-gas chromatographies; Mineral oil aromatic hydrocarbon; Mineral oil saturated hydrocarbon; Oil hydrocarbons; Saturated hydrocarbons; Analytical Chemistry; Biochemistry

Abstract :

[en] Mineral oil hydrocarbons (MOH) contain a wide structural diversity of molecules, for which the reference method of analysis is the online coupled liquid chromatography-gas chromatography with flame ionization detection (LC-GC-FID). These compounds are very heterogeneous from a toxicological viewpoint, and an accurate risk assessment when dealing with a MOH contamination can only be performed if sufficient information is available on the types of structures present (i.e., number of carbons, degree of alkylation, number of aromatic rings). Unfortunately, the separation performances of the current LC-GC-FID method are insufficient for such characterization, not even mentioning the possible coelution of interfering compounds which additionally hinder MOH determination. Comprehensive two-dimensional gas chromatography (GC × GC), while mostly used for confirmation purposes in the past, starts to prove its relevance for overcoming the weaknesses of the LC-GC method and reaching even better the analytical requirements defined in the latest EFSA opinion. The present paper therefore aims at highlighting how GC × GC has contributed to the understanding of the MOH topic, how it has developed to meet the requirements of MOH determination, and how it could play a role in the field for overcoming many of the current analytical and toxicological challenges related to the topic.

Research center :

TERRA Research Centre. Chimie des agro-biosystèmes - ULiège

Disciplines :

Chemistry

Author, co-author :

Bauwens, Grégory ^✱; Université de Liège - ULiège > Département GxABT > Chemistry for Sustainable Food and Environmental Systems (CSFES)

Gorska, Aleksandra ^✱; Université de Liège - ULiège > Gembloux Agro-Bio Tech > Gembloux Agro-Bio Tech

Purcaro, Giorgia ; Université de Liège - ULiège > TERRA Research Centre > Chemistry for Sustainable Food and Environmental Systems (CSFES)

^✱ These authors have contributed equally to this work.

Language :

English

Title :

The role of comprehensive two-dimensional gas chromatography in mineral oil determination.

Publication date :

06 May 2023

Journal title :

Analytical and Bioanalytical Chemistry

ISSN :

1618-2642

eISSN :

1618-2650

Publisher :

Springer Science and Business Media Deutschland GmbH, Germany

Peer reviewed :

Peer Reviewed verified by ORBi

Additional URL :

https://link.springer.com/content/pdf/10.1007/s00216-023-04718-3.pdf

Funders :

F.R.S.-FNRS - Fonds de la Recherche Scientifique [BE]

Funding number :

T.0187.23

Funding text :

This work is supported by Fonds de la Recherche Scientifique Belgique (FNRS) (PDR projects-ToxAnaMOH, T.0187.23).

Data Set :

10.1007/s00216-023-04718-3

Available on ORBi :

since 22 May 2023

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