Dubus, A., J. M. Wilkin, X. Raquet, S. Normark, and J. M. Frere. 1994. Catalytic mechanism of active-site serine beta-lactamases: role of the conserved hydroxy group of the Lys-Thr(Ser)-Gly triad. Biochem. J. 301:485-494.
Fonze, E., P. Charlier, Y. To'th, M. Vermeire, X. Raquet, A. Dubus, and J. M. Frere. 1995. TEM1 beta-lactamase structure solved by molecular replacement and refined structure of the S235A mutant. Acta Crystallogr. Sect. D 51:682-694.
McMurry, L., R. E. Petrucci, Jr., and S. B. Levy. 1980. Active efflux of tetracycline encoded by four genetically different tetracycline resistance determinants in Escherichia coli. Proc. Natl. Acad. Sci. USA 77:3974-3977.
Paulsen, I. T., M. H. Brown, and R. A. Skurray. 1996. Proton-dependent multidrug efflux systems. Microbiol. Rev. 60:575-608.
Sapunaric, F. M., M. L. Aldema-Ramos, and L. M. McMurry. 2005. Tetracycline resistance: efflux, mutation, and other mechanisms, p. 3-18. In D. G. White, M. N. Alekshun, and P. F. McDermott (ed.), Frontiers in antimicrobial resistance: a tribute to Stuart B. Levy. ASM Press, Washington, DC.
Sapunaric, F. M., and S. B. Levy. 2003. Second-site suppressor mutations for the serine 202 to phenylalanine substitution within the interdomain loop of the tetracycline efflux protein Tet(C). J. Biol. Chem. 278:28588-28592.
Sapunaric, F. M., and S. B. Levy. 2005. Substitutions in the interdomain loop of the Tn10 TetA efflux transporter alter tetracycline resistance and substrate specificity. Microbiology 151:2315-2322.
Someya, Y., T. Kimura-Someya, and A. Yamaguchi. 2000. Role of the charge interaction between Arg(70) and Asp(120) in the Tn10-encoded metal-tetracycline/H(+) antiporter of Escherichia coli. J. Biol. Chem. 275:210-214.
Someya, Y., and A. Yamaguchi. 1996. Mercaptide formed between the residue Cys70 and Hg2+ or Co2+ behaves as a functional positively charged side chain operative in the Arg70→Cys mutant of the metal-tetracycline/H+ antiporter of Escherichia coli. Biochemistry 35:9385-9391.
Tamura, N., S. Konishi, S. Iwaki, T. Kimura-Someya, S. Nada, and A. Yamaguchi. 2001. Complete cysteine-scanning mutagenesis and site-directed chemical modification of the Tn10-encoded metal-tetracycline/H + antiporter. J. Biol. Chem. 276:20330-20339.
Tuckman, M., P. J. Petersen, and S. J. Projan. 2000. Mutations in the interdomain loop region of the tetA(A) tetracycline resistance gene increase efflux of minocycline and glycylcyclines. Microb. Drug Resist. 6:277-282.
Yamaguchi, A., Y. Iwasaki-Ohba, N. Ono, M. Kaneko-Ohdera, and T. Sawai. 1991. Stoichiometry of metal-tetracycline/H+ antiport mediated by transposon Tn10-encoded tetracycline resistance protein in Escherichia coli. FEBS Lett. 282:415-418.
Yamaguchi, A., N. Ono, T. Akasaka, T. Noumi, and T. Sawai. 1990. Metal-tetracycline/H+ antiporter of Escherichia coli encoded by a transposon, Tn10. The role of the conserved dipeptide, Ser65-Asp66, in tetracycline transport. J. Biol. Chem. 265:15525-15530.
Yamaguchi, A., R. O'Yauchi, Y. Someya, T. Akasaka, and T. Sawai. 1993. Second-site mutation of Ala-220 to Glu or Asp suppresses the mutation of Asp-285 to Asn in the transposon Tn10-encoded metal-tetracycline/H + antiporter of Escherichia coli. J. Biol. Chem. 268:26990-26995.
