[en] The training program of Thoroughbred (TB) flat racehorses includes exercise sessions of low to high intensities, short to long distances and rest periods. This field study aimed at assessing the metabolic responses induced by two training sessions of different intensity, widely used in the training of TB.
Blood samples were collected in two groups of six and five TB at rest and 30 minutes after a high-intensity (gallop, 1.400m) and a moderate intensity (canter, 2.500m) exercise, respectively. Plasma samples were analyzed using an untargeted metabolomic approach based on liquid chromatography coupled with mass spectrometry. Exercise intensity was evaluated by monitoring heart rate and speed as well as exercise-induced changes of targeted biochemical parameters (e.g. lactatemia, hematocrit, etc.). Unsupervised principal component analysis performed on all detected features revealed changes in metabolome from pre- to post-exercise plasma samples with a greater extent following high-intensity exercise. In addition, supervised analyses revealed changes of 172 features by high-intensity exercise, among them 35 metabolites were identified using standard metabolites comparisons. These metabolites were mainly related to the chemical class of amino acids, nucleic acids and vitamins. Moderate intensity exercise induced changes of only a few metabolites, related to lipids and amino acids. In conclusion, TB training sessions induce differential changes in energy pathways depending on the intensity and the distance of the exercise.
Disciplines :
Veterinary medicine & animal health
Author, co-author :
Bonhomme, Maëlle ; Université de Liège - ULiège > Fundamental and Applied Research for Animals and Health (FARAH) > FARAH: Médecine vétérinaire comparée
Patarin, Florence ; Université de Liège - ULiège > Fundamental and Applied Research for Animals and Health (FARAH)
Kruse, Caroline ; Université de Liège - ULiège > Fundamental and Applied Research for Animals and Health (FARAH) > FARAH: Médecine vétérinaire comparée
François, Anne-Christine ; Université de Liège - ULiège > Fundamental and Applied Research for Animals and Health (FARAH) > FARAH: Médecine vétérinaire comparée
Renaud, Benoît ; Université de Liège - ULiège > Fundamental and Applied Research for Animals and Health (FARAH) > FARAH: Médecine vétérinaire comparée
Couroucé, Anne; Oniris, École Nationale Vétérinaire Agroalimentaire et de l’alimentation ; Biotargen, Université de Caen Normandie
Richard, Eric A.; LABÉO (Frank Duncombe) ; Biotargen, Université de Caen Normandie
Wouters, Clovis ; Université de Liège - ULiège > Fundamental and Applied Research for Animals and Health (FARAH) > FARAH: Médecine vétérinaire comparée
Votion, Dominique ; Université de Liège - ULiège > Fundamental and Applied Research for Animals and Health (FARAH) > FARAH: Médecine vétérinaire comparée
Language :
English
Title :
Metabolomic investigation of exercise-induced response to moderate and high intensities training sessions in Thoroughbred flat racehorses
Publication date :
15 December 2022
Event name :
FARAH-Day 2022
Event place :
Liège, Belgium
Event date :
15/12/2022
Peer reviewed :
Editorial reviewed
Funders :
F.R.S.-FNRS - Fonds de la Recherche Scientifique IFCE - Institut Français du Cheval et de l'Équitation ULiège FSR - Université de Liège. Fonds spécial pour la recherche
This website uses cookies to improve user experience. Read more
Save & Close
Accept all
Decline all
Show detailsHide details
Cookie declaration
About cookies
Strictly necessary
Performance
Strictly necessary cookies allow core website functionality such as user login and account management. The website cannot be used properly without strictly necessary cookies.
This cookie is used by Cookie-Script.com service to remember visitor cookie consent preferences. It is necessary for Cookie-Script.com cookie banner to work properly.
Performance cookies are used to see how visitors use the website, eg. analytics cookies. Those cookies cannot be used to directly identify a certain visitor.
Used to store the attribution information, the referrer initially used to visit the website
Cookies are small text files that are placed on your computer by websites that you visit. Websites use cookies to help users navigate efficiently and perform certain functions. Cookies that are required for the website to operate properly are allowed to be set without your permission. All other cookies need to be approved before they can be set in the browser.
You can change your consent to cookie usage at any time on our Privacy Policy page.