Koch, Nathan ; Université de Liège - ULiège > Département de pharmacie > Pharmacie galénique ; Université de Liège - ULiège > Unités de recherche interfacultaires > Centre Interdisciplinaire de Recherche sur le Médicament (CIRM)
Jennotte, Olivier ; Université de Liège - ULiège > Unités de recherche interfacultaires > Centre Interdisciplinaire de Recherche sur le Médicament (CIRM)
Toussaint, Céline
Lechanteur, Anna ; Université de Liège - ULiège > Département de pharmacie > Pharmacie galénique ; Université de Liège - ULiège > Unités de recherche interfacultaires > Centre Interdisciplinaire de Recherche sur le Médicament (CIRM)
Evrard, Brigitte ; Université de Liège - ULiège > Département de pharmacie > Pharmacie galénique ; Université de Liège - ULiège > Unités de recherche interfacultaires > Centre Interdisciplinaire de Recherche sur le Médicament (CIRM)
Language :
English
Title :
Production challenges of tablets containing lipid excipients: case study using cannabidiol as drug model
Akhlaquer Rahman, M., Harwansh, R., Aamir Mirza, M., Hussain, S., Hussain, A., Oral lipid based drug delivery system (LBDDS): formulation, characterization and application: a review. Curr. Drug Deliv. 8 (2011), 330–345, 10.2174/156720111795767906.
Aldosari, B.N., Almurshedi, A.S., Alfagih, I.M., AlQuadeib, B.T., Altamimi, M.A., Imam, S.S., Hussain, A., Alqahtani, F., Alzait, E., Alshehri, S., Formulation of Gelucire®-based solid dispersions of atorvastatin calcium. In vitro dissolution and in vivo bioavailability study. AAPS PharmSciTech 22 (2021), 1–13, 10.1208/s12249-021-02019-5.
Atalay, S., Jarocka-karpowicz, I., Skrzydlewskas, E., Antioxidative and anti-inflammatory properties of cannabidiol. Antioxidants 9 (2020), 1–20, 10.3390/antiox9010021.
Avgerinos, T., Kantiranis, N., Panagopoulou, A., Malamataris, S., Kachrimanis, K., Nikolakakis, I., Mechanical properties and drug release of venlafaxine HCl solid mini matrices prepared by hot-melt extrusion and hot or ambient compression. Drug Dev. Ind. Pharm. 44 (2018), 338–348, 10.1080/03639045.2017.1391839.
Baumgartner, A., Planinšek, O., Application of commercially available mesoporous silica for drug dissolution enhancement in oral drug delivery. Eur. J. Pharm. Sci., 167, 2021, 10.1016/j.ejps.2021.106015.
Bertoni, S., Albertini, B., Passerini, N., Different BCS class II drug-gelucire solid dispersions prepared by spray congealing: evaluation of solid state properties and in vitro performances. Pharmaceutics 12 (2020), 1–20, 10.3390/pharmaceutics12060548.
Cherniakov, I., Izgelov, D., Barasch, D., Davidson, E., Domb, A.J., Hoffman, A., Piperine-pro-nanolipospheres as a novel oral delivery system of cannabinoids: Pharmacokinetic evaluation in healthy volunteers in comparison to buccal spray administration. J. Control. Release 266 (2017), 1–7, 10.1016/j.jconrel.2017.09.011.
De Prá, M.A.A., Vardanega, R., Loss, C.G., Lipid-based formulations to increase cannabidiol bioavailability: In vitro digestion tests, pre-clinical assessment and clinical trial. Int. J. Pharm., 609, 2021, 10.1016/j.ijpharm.2021.121159.
Evrard, B., Delattre, L., In vitro evaluation of lipid matrices for the development of a sustained-release sulfamethazine bolus for lambs. Drug Dev. Ind. Pharm. 22 (1996), 111–118, 10.3109/03639049609041980.
Feng, W., Qin, C., Chu, Y.J., Berton, M., Lee, J.B., Zgair, A., Bettonte, S., Stocks, M.J., Constantinescu, C.S., Barrett, D.A., Fischer, P.M., Gershkovich, P., Natural sesame oil is superior to pre-digested lipid formulations and purified triglycerides in promoting the intestinal lymphatic transport and systemic bioavailability of cannabidiol. Eur. J. Pharm. Biopharm. 162 (2021), 43–49, 10.1016/j.ejpb.2021.02.013.
Fernandes, M.F., Chan, J.Z., Hung, C.C.J., Tomczewski, M.V., Duncan, R.E., Effect of cannabidiol on apoptosis and cellular interferon and interferon-stimulated gene responses to the SARS-CoV-2 genes ORF8, ORF10 and M protein. Life Sci., 301, 2022, 120624, 10.1016/j.lfs.2022.120624.
Gershkovich, P., Qadri, B., Yacovan, A., Amselem, S., Hoffman, A., Different impacts of intestinal lymphatic transport on the oral bioavailability of structurally similar synthetic lipophilic cannabinoids: Dexanabinol and PRS-211,220. Eur. J. Pharm. Sci. 31 (2007), 298–305, 10.1016/j.ejps.2007.04.006.
Gumaste, S.G., Dalrymple, D.M., Serajuddin, A.T.M., Development of solid SEDDS, V: Compaction and drug release properties of tablets prepared by adsorbing lipid-based formulations onto neusilin® US2. Pharm. Res. 30 (2013), 3186–3199, 10.1007/s11095-013-1106-4.
Hauss, D.J., Fogal, S.E., Ficorilli, J.V., Price, C.A., Roy, T., Jayaraj, A.A., Keirns, J.J., Lipid-based delivery systems for improving the bioavailability and lymphatic transport of a poorly water-soluble LTB4 inhibitor. J. Pharm. Sci. 87 (1998), 164–169, 10.1021/js970300n.
Izgelov, D., Freidman, M., Hoffman, A., Investigation of cannabidiol gastro retentive tablets based on regional absorption of cannabinoids in rats. Eur. J. Pharm. Biopharm. 152 (2020), 229–235, 10.1016/j.ejpb.2020.05.010.
Jennotte, O., Koch, N., Lechanteur, A., Evrard, B., Development of amorphous solid dispersions of cannabidiol: Influence of the carrier, the hot-melt extrusion parameters and the use of a crystallization inhibitor. J. Drug Deliv. Sci. Technol., 71, 2022, 103372, 10.1016/j.jddst.2022.103372.
Jivraj, M., Martini, L.G., Thomson, C.M., An overview of the different excipients useful for the direct compression of tablets. Pharm. Sci. Technol. Today 3 (2000), 58–63, 10.1016/S1461-5347(99)00237-0.
Kirkland, A.E., Fadus, M.C., Gruber, S.A., Gray, K.M., Wilens, T.E., Squeglia, L.M., A scoping review of the use of cannabidiol in psychiatric disorders. Psychiatry Res., 308, 2022, 114347, 10.1016/j.psychres.2021.114347.
Koch, N., Jennotte, O., Gasparrini, Y., Vandenbroucke, F., Lechanteur, A., Evrard, B., Cannabidiol aqueous solubility enhancement: comparison of three amorphous formulations strategies using different type of polymers. Int. J. Pharm., 589, 2020, 10.1016/j.ijpharm.2020.119812.
Koch, N., Jennotte, O., Grignard, B., Lechanteur, A., Evrard, B., Impregnation of mesoporous silica with poor aqueous soluble molecule using pressurized carbon dioxide: Is the solubility in the supercritical and subcritical phase a critical parameter?. Eur. J. Pharm. Sci., 150, 2020, 10.1016/j.ejps.2020.105332.
Kok, L.Y., Bannigan, P., Sanaee, F., Evans, J.C., Dunne, M., Regenold, M., Ahmed, L., Dubins, D., Allen, C., Dunne, M., Regenold, M., Ahmed, L., Dubins, D., Allen, C., Development and pharmacokinetic evaluation of a self-nanoemulsifying drug delivery system for the oral delivery of cannabidiol. Eur. J. Pharm. Sci., 106058, 2021, 10.1016/j.ejps.2021.106058.
Kostelanská, K., Prudilová, B.B., Holešová, S., Vlček, J., Vetchý, D., Gajdziok, J., Comparative study of powder carriers physical and structural properties. Pharmaceutics, 14, 2022, 818, 10.3390/pharmaceutics14040818.
Liu, L., Li, J., Zhao, M. hui, Xu, H., Li, L. sen, Wang, S. ning, 2016. Loading of tacrolimus containing lipid based drug delivery systems into mesoporous silica for extended release. Asian J. Pharm. Sci. 11, 751–759. https://doi.org/10.1016/j.ajps.2016.07.005.
Markl, D., Strobel, A., Schlossnikl, R., Bøtker, J., Bawuah, P., Ridgway, C., Rantanen, J., Rades, T., Gane, P., Peiponen, K.E., Zeitler, J.A., Characterisation of pore structures of pharmaceutical tablets: a review. Int. J. Pharm. 538 (2018), 188–214, 10.1016/j.ijpharm.2018.01.017.
Partheniadis, I., Vergkizi, S., Lazari, D., Reppas, C., Nikolakakis, I., Formulation, characterization and antimicrobial activity of tablets of essential oil prepared by compression of spray-dried powder. J. Drug Deliv. Sci. Technol. 50 (2019), 226–236, 10.1016/j.jddst.2019.01.031.
Petrovick, G.F., Kleinebudde, P., Breitkreutz, J., Orodispersible tablets containing taste-masked solid lipid pellets with metformin hydrochloride: Influence of process parameters on tablet properties. Eur. J. Pharm. Biopharm. 122 (2018), 137–145, 10.1016/j.ejpb.2017.10.018.
Poovi, G., Damodharan, N., Lipid nanoparticles: A challenging approach for oral delivery of BCS Class-II drugs. Futur. J. Pharm. Sci. 4 (2018), 191–205, 10.1016/j.fjps.2018.04.001.
Porter, C.J.H., Trevaskis, N.L., Charman, W.N., Lipids and lipid-based formulations: Optimizing the oral delivery of lipophilic drugs. Nat. Rev. Drug Discov. 6 (2007), 231–248, 10.1038/nrd2197.
Pouton, C.W., Lipid formulations for oral administration of drugs: Non-emulsifying, self-emulsifying and “self-microemulsifying” drug delivery systems. Eur. J. Pharm. Sci. 11 (2000), 93–98, 10.1016/S0928-0987(00)00167-6.
Pouton, C.W., Formulation of poorly water-soluble drugs for oral administration: Physicochemical and physiological issues and the lipid formulation classification system. Eur. J. Pharm. Sci. 29 (2006), 278–287, 10.1016/j.ejps.2006.04.016.
Rajput, A., Pingale, P., Telange, D., Chalikwar, S., Borse, V., Lymphatic transport system to circumvent hepatic metabolism for oral delivery of lipid-based nanocarriers. J. Drug Deliv. Sci. Technol., 66, 2021, 102934, 10.1016/j.jddst.2021.102934.
Sander, C., Holm, P., Porous magnesium aluminometasilicate tablets as carrier of a cyclosporine self-emulsifying formulation. AAPS PharmSciTech 10 (2009), 1388–1395, 10.1208/s12249-009-9340-0.
Shaker, M.A., Dissolution and bioavailability enhancement of Atorvastatin: Gelucire semi-solid binary system. J. Drug Deliv. Sci. Technol. 43 (2018), 178–184, 10.1016/j.jddst.2017.10.003.
Sinka, I.C., Pitt, K.G., Cocks, A.C.F., 2007. Chapter 22 The strength of pharmaceutical tablets. Handb. Powder Technol. 12, 941–970. https://doi.org/10.1016/S0167-3785(07)12025-X.
Trevaskis, N.L., Charman, W.N., Porter, C.J.H., Lipid-based delivery systems and intestinal lymphatic drug transport: a mechanistic update. Adv. Drug Deliv. Rev. 60 (2008), 702–716, 10.1016/j.addr.2007.09.007.
Valenti, C., Billi, M., Pancrazi, G.L., Calabria, E., Armogida, N.G., Tortora, G., Pagano, S., Barnaba, P., Marinucci, L., Biological effects of cannabidiol on human cancer cells: systematic review of the literature. Pharmacol. Res., 181, 2022, 106267, 10.1016/j.phrs.2022.106267.
Wang, J., Wen, H., Desai, D., Lubrication in tablet formulations. Eur. J. Pharm. Biopharm. 75 (2010), 1–15, 10.1016/j.ejpb.2010.01.007.
