Keywords :
R8P8USM8FR (Paliperidone Palmitate); Eosinophilia/chemically induced/complications; Exudates and Transudates; Humans; Leukocyte Count; Paliperidone Palmitate/adverse effects; Pleural Effusion/chemically induced/complications/diagnosis; case report; drug-induced eosinophilic pleural effusion; eosinophilic pleural effusion; iatrogenic pleural effusion; paliperidone palmitate
Abstract :
[en] BACKGROUND: Eosinophilic pleural effusions are defined by an eosinophil count ≥ 10% in pleural fluid and represent approximately 10% of exudative pleural effusions. They are associated with a large spectrum of etiologies, both benign and malignant. Drug-induced eosinophilic pleural effusions remain rarely described. OBJECTIVE AND METHODS: After ruling out other causes with a careful diagnostic assessment, we retain paliperidone as the etiology, given the disappearance of the pleural effusion after drug discontinuation. RESULTS: We report the first case of eosinophilic pleural effusion induced by paliperidone palmitate treatment. CONCLUSION: After considering other etiologies, drug-induced eosinophilic pleural effusion should be sought.
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