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Article (Scientific journals)
Caractères chimiques et propriétés pharmacologiques de plusieurs alcaloïdes extraits du Strychnos usambarensis
Dubois, Michel; Ginion, Ch.; Angenot, Luc et al.
1974 • In Archives Internationales de Physiologie et de Biochimie, 82, p. 823-830
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https://hdl.handle.net/2268/29679
DOI
10.3109/13813457409072330
PubMed
4142700
 

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Keywords :
Strychnos usambarensis; usambarensine pharmacology; dihydrotoxiferine pharmacology; calebassine pharmacology
Abstract :
[en] The pharmacological properties of ten tertiary, hybrid and quaternary alkaloids isolated from the barks of Strychnos usambarensis roots have been investigated. Usambarensine, a tertiary bis-indole alkaloid, inhibits the muscarinic effects of acetylcholine. Four ammonium quaternary products (C-dihydrotoxiferine, afrocurarine ( a new compound), C-curarine and C-calebassine are potent curarizing agents.
Disciplines :
Pharmacy, pharmacology & toxicology
Author, co-author :
Dubois, Michel ;  Université de Liège - ULiège > Gynécologie-Obstétrique CHR
Ginion, Ch.
Angenot, Luc  ;  Université de Liège - ULiège > Département de pharmacie > Pharmacognosie
Van Dorsser, W.
Dresse, Albert ;  Université de Liège - ULiège > Services généraux (Faculté de médecine) > Relations académiques et scientifiques (Médecine)
Language :
French
Title :
Caractères chimiques et propriétés pharmacologiques de plusieurs alcaloïdes extraits du Strychnos usambarensis
Alternative titles :
[en] Chemical and pharmacological properties of some alkaloids extracted from Strychnos usambarensis
Publication date :
1974
Journal title :
Archives Internationales de Physiologie et de Biochimie
ISSN :
0003-9799
Publisher :
Vaillant Carmanne, Liège, Belgium
Volume :
82
Pages :
823-830
Peer reviewed :
Peer Reviewed verified by ORBi
Available on ORBi :
since 05 May 2010

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