Reference : Caractères chimiques et propriétés pharmacologiques de plusieurs alcaloïdes extraits ...
Scientific journals : Article
Human health sciences : Pharmacy, pharmacology & toxicology
Caractères chimiques et propriétés pharmacologiques de plusieurs alcaloïdes extraits du Strychnos usambarensis
[en] Chemical and pharmacological properties of some alkaloids extracted from Strychnos usambarensis
Dubois, Michel [Université de Liège - ULiège > > Gynécologie-Obstétrique CHR >]
Ginion, Ch. [ > > ]
Angenot, Luc mailto [Université de Liège - ULiège > Département de pharmacie > Pharmacognosie >]
Van Dorsser, W. [ > > ]
Dresse, Albert mailto [Université de Liège - ULiège > Services généraux (Faculté de médecine) > Relations académiques et scientifiques (Médecine) >]
Archives Internationales de Physiologie et de Biochimie
Vaillant Carmanne
Yes (verified by ORBi)
[en] Strychnos usambarensis ; usambarensine pharmacology ; dihydrotoxiferine pharmacology ; calebassine pharmacology
[en] The pharmacological properties of ten tertiary, hybrid and quaternary alkaloids isolated from the barks of Strychnos usambarensis roots have been investigated. Usambarensine, a tertiary bis-indole alkaloid, inhibits the muscarinic effects of acetylcholine. Four ammonium quaternary products (C-dihydrotoxiferine, afrocurarine ( a new compound), C-curarine and C-calebassine are potent curarizing agents.

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Archives internat. de Physiologie et de biochimie 1974 pp 823_830.pdfPublisher postprint264.95 kBRequest copy

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