[en] The purpose of this study was to evaluate the efficacy and safety of photobiomodulation as an adjuvant treatment for primary headache. A systematic review of randomized clinical trials was performed. For such, electronic searches were performed in the MEDLINE, Embase, Cochrane Library, LILACS, PEDro, PsycInfo, Clinicaltrials.gov., and WHO/ICTRP databases, with no restrictions imposed regarding language or year of publication. We included studies that assessed any photobiomodulation therapy as an adjuvant treatment for primary headache compared to sham treatment, no treatment, or another intervention. The methodological assessment was conducted using the Cochrane Risk of Bias tool. The certainty of the evidence was classified using the GRADE approach. Four randomized clinical trials were included. Most of the included studies had an overall high risk of bias. Compared to sham treatment, photobiomodulation had a clinically important effect on pain in individuals with primary headache. Despite the benefits reported for other outcomes, the estimates were imprecise, and the certainty of the evidence was graded as low. These findings are considered insufficient to support the use of photobiomodulation in the treatment of primary headache. Randomized clinical trials, with higher methodological quality, are needed to enhance the reliability of the estimated effects.
Disciplines :
Dentistry & oral medicine
Author, co-author :
Gomes, Andréa Oliver; Postgraduate Program in Rehabilitation Sciences, Universidade Nove de Julho (UNINOVE), Street Vergueiro, 235/249-Liberdade, São Paulo 05503-900, Brazil
Martimbianco, Ana Luiza Cabrera; Postgraduate Program in Health and Environment, Universidade Metropolitana de Santos (UNIMES), São Paulo 05503-900, Brazil
Brugnera Junior, Aldo ; Physics Institute of São Carlos (IFSC/USP), Universidade de São Paulo, São Paulo 05503-900, Brazil
Horliana, Anna Carolina Ratto Tempestini ; Postgraduate Program in Biophotonics Applied to Health Sciences, Universidade Nove de Julho (UNINOVE), São Paulo 05503-900, Brazil
da Silva, Tamiris; Postgraduate Program in Rehabilitation Sciences, Universidade Nove de Julho (UNINOVE), Street Vergueiro, 235/249-Liberdade, São Paulo 05503-900, Brazil
Santos, Elaine Marcílio; Postgraduate Program in Health and Environment, Universidade Metropolitana de Santos (UNIMES), São Paulo 05503-900, Brazil
Fragoso, Yara Dadalti; Postgraduate Program in Health and Environment, Universidade Metropolitana de Santos (UNIMES), São Paulo 05503-900, Brazil
Fernandes, Kristianne Porta Santos; Postgraduate Program in Biophotonics Applied to Health Sciences, Universidade Nove de Julho (UNINOVE), São Paulo 05503-900, Brazil
Namour, Samir ; Université de Liège - ULiège > Département des sciences dentaires
Bussadori, Sandra Kalil ; Postgraduate Program in Rehabilitation Sciences, Universidade Nove de Julho (UNINOVE), Street Vergueiro, 235/249-Liberdade, São Paulo 05503-900, Brazil ; Postgraduate Program in Biophotonics Applied to Health Sciences, Universidade Nove de Julho (UNINOVE), São Paulo 05503-900, Brazil
Language :
English
Title :
Photobiomodulation for the Treatment of Primary Headache: Systematic Review of Randomized Clinical Trials.
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