probiotics; prebiotics; synbiotics; antioxidants; metabolites; human health; animal health
Abstract :
[en] Antioxidants are often associated with a variety of anti-aging compounds that can ensure human and animal health longevity. Foods and diet supplements from animals and plants are the common exogenous sources of antioxidants. However, microbial-based products, including probiotics and their derivatives, have been recognized for their antioxidant properties through numerous studies and clinical trials. While the number of publications on probiotic antioxidant capacities and action mechanisms is expanding, that of synbiotics combining probiotics with prebiotics is still emerging. Here, the antioxidant metabolites and properties of synbiotics, their modes of action, and their different effects on human and animal health are reviewed and discussed. Synbiotics can generate almost unlimited possibilities of antioxidant compounds, which may have superior performance compared to those of their components through additive or complementary effects, and especially by synergistic actions. Either combined with antioxidant prebiotics or not, probiotics can convert these substrates to generate antioxidant compounds with superior activities. Such synbiotic-based new routes for supplying natural antioxidants appear relevant and promising in human and animal health prevention and treatment. A better understanding of various component interactions within synbiotics is key to generating a higher quality, quantity, and bioavailability of antioxidants from these biotic sources.
Disciplines :
Life sciences: Multidisciplinary, general & others
Author, co-author :
Mounir, Majid
Ibijbijen, Amal
Farih, Kawtar
Rabetafika, Holy N.
Razafindralambo, Hary ; Université de Liège - ULiège > Département GxABT > Microbial technologies
Language :
English
Title :
Synbiotics and their Antioxidant Properties, Mechanisms, and Benefits on Human and Animal Health: A Narrative Review
Publication date :
09 October 2022
Journal title :
Biomolecules
eISSN :
2218-273X
Publisher :
MDPI AG
Volume :
12
Issue :
10
Pages :
1443
Peer reviewed :
Peer Reviewed verified by ORBi
Development Goals :
1. No poverty 2. Zero hunger 3. Good health and well-being 9. Industry, innovation and infrastructure 17. Partnerships for the goals
HE - 101059232 - URBANE - One Health approaches to support agroecological transformation of peri-urban farming
Funders :
EU - European Union
Commentary :
Article publié dans un numéro spécial intitulé "Probiotics and their Metabolites" de Biomolecules (MDPI) dont RAZAFINDRALAMBO Hary est l'éditeur invité.
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