The interchromatin granules.

In the present review, we report on the data obtained on the most prominent elements observed in the interchromatin spaces: the interchromatin granules (IGs). Special emphasis is placed on the recent contributions of immunocytochemical and in situ hybridization methods towards elucidating the composition and the behavior of these nuclear substructures during the cell cycle. The possible roles of IGs in the cell nucleus are also discussed.