oncology; radiation oncology; head and neck cancer; neoadjuvant chemotherapy; cancer chemotherapy; cancer radiotherapy; prediction of chemotherapy response; prediction of radiation results; oncologie; radiothérapie oncologie; cancers de la tête et du cou; chimiothérapie néoadjuvante; chimiothérapie anti-cancéreuse; radiothérapie anti-cancéreuse; prédiction de la réponse à la chimiothérapie; prédiction du résultat de la radiothérapie
Abstract :
[en] Advanced head and neck cancer patients received exclusive radiotherapy after a low dose neoadjuvant chemotherapy. Analysis of complete tumour control shows a significant link with the chemotherapy response. The predictive power was present for primary tumours and nodes. Patients achieving complete radiotherapy control with a major chemotherapy response had a far better prognosis at 3 years. Selection of cases curable without undergoing mutilating surgery appears possible.
Disciplines :
Oncology
Author, co-author :
Deneufbourg, Jean-Marie ; Université de Liège - ULiège > Département des sciences cliniques > Radiothérapie
Language :
English
Title :
Neoadjuvant chemotherapy in head and neck cancers : prediction of radiation response and basis for selective avoidance of mutilating surgery
Publication date :
08 March 1989
Event name :
25th Annual Meeting of the American Society of Clinical Oncology
Event organizer :
American Society of Clinical Oncology ASCO
Event place :
San Francisco, United States - California
Event date :
21 - 23 mai 1989
Event number :
25
Audience :
International
Main work title :
Proceedings of 25th ASCO meeting SAN FRANCISCO
Editor :
Coltman, A. Jr; ASCO President
Publishing director :
Leventhal, Brigid
Publisher :
Saunders Company, San Francisco, United States - California
