oncology; head and neck cancers; radiation oncology; cancer chemotherapy; neoadjuvant chemotherapy; bleomycin; vepesid; cis-platinum; prediction of radiation response; oncologie; cancers de la tête et du cou; radiothérapie oncologique; chimiothérapie anti-cancéreuse; chimiothérapie néo-adjuvante; bléomycine; prédiction de la réponse à la radiothérapie
Abstract :
[en] 184 consecutive head and neck cancer patients received a polychemotherapy at low dosage prior to radical treatment with minimal side-effects. Results of subsequent exclusive radiotherapy showed strictly dependant on chemotherapy response : complete control 82% in C+ versus 39% in C- . A benefit in survival of 10 to 15 % exists at 3 years as compared to our own controls. Predictive neoadjuvant might be of value for treatment individualization. individualization.chemotherapy might
Disciplines :
Oncology
Author, co-author :
Deneufbourg, Jean-Marie ; Université de Liège - ULiège > > Oncologie - Radiothérapie (Succ. Closon)
Language :
English
Title :
Low dose neoadjuvant chemotherapy in head and neck cancers : anti-tumour activity, prediction of radiotherapy response and influence on survival.
Publication date :
1988
Event name :
2nd International Congress on Neoadjuvant Chemotherapy
Event organizer :
Jacquillat, Claude Weil , Maryse Khayat, David
Event place :
Paris, France
Event date :
19 - 21 février 1988
Event number :
2
Audience :
International
Main work title :
Neoadjuvant Chemotherapy
Editor :
Weil, Maryse; Hôpital Pitié Salpétrière Paris > Service d'oncologie médicale
Khayat, David; Hôpital Pitié Salpétrière Paris > Service d'oncologie médicale
Jacquillat, Claude; Hôpital Pitié Salpétrière Paris > Service d'oncologie médicale
Publisher :
INSERM, Paris, France John Libbey Eurotext, Londres, United Kingdom
