radiotherapy; surgery; chemotherapy; immunity of cured animals:; transplantable murine tumours; abscopal effect of irradiation; by-stander effect of radiotherapy; active immunotherapy
Abstract :
[en] In 2 murine transplantable systems, specific immunity of animals cured of a primary tumour depends on the therapeutic mode. High single doses of radiations confer a significant advantage over surgery as well as over chemotherapy. Pre-operative irradiation boosts anti-tumour immunity to a level similar of exclusive radiotherapy group. Late recurrences and metastasis might be influenced by taking advantage of the immunological effects of radiotherapy.
Disciplines :
Oncology
Author, co-author :
Deneufbourg, Jean-Marie ; ULiège - Université de Liège > Hôpital Universitaire de Bavière > Service de Radiothérapie
Language :
English
Title :
Influence of treatment mode on host immunity after cure from transplantable tumours : the advantage radiotherapy over surgery and chemotherapy
Publication date :
15 October 1984
Event name :
Conference on treatment of metastasis : problems and prospects
Event organizer :
Imperial Cancer Research Fund and Institute of Cancer Research
Event place :
Londres, United Kingdom
Event date :
15 - 17 avril 1984
By request :
Yes
Audience :
International
Main work title :
Treatment of metastasis : problems and prospects
Editor :
Hellmann, K. ; Eccles, S.A.; Imperial Cancer Research Fund London > Institute of Cancer Research Sutton
