[en] Castrated quail were treated with Silastic implants filled with testosterone (T) in association with injections of the aromatase inhibitors, R76713 (racemic vorozole; 1 mg/kg twice a day) or 4-hydroxyandrostenedione (OHA; 5 mg/bird twice a day).
Foidart, Agnès ; Université de Liège - ULiège > Services généraux (Faculté de médecine) > Service administratif de la Faculté (Médecine)
Harada, N.
Balthazart, Jacques ; Université de Liège - ULiège > Département des sciences biomédicales et précliniques > Biologie de la différenciation sexuelle du cerveau
Language :
English
Title :
Effects of Steroidal and Non Steroidal Aromatase Inhibitors on Sexual Behavior and Aromatase-Immunoreactive Cells and Fibers in the Quail Brain
Adkins (1977) Effects of diverse androgens on the sexual behavior and morphology of castrated male quail. Horm. Behav. 8:201-207.
Adkins, Adler (1972) Hormonal control of behavior in the Japanese quail. J. Comp. Physiol. Psychol. 81:27-36.
Balthazart (1989) Steroid metabolism and the activation of social behavior. Advances in Comparative and Environmental Physiology , 2nd edn., J. Balthazart, Springer Verlag, Berlin; 3:105-159.
Balthazart, Ball (1992) Is dopamine interacting with aromatase to control of sexual behavior in male quail?. Poultry Sci. Rev. 4:217-233.
Balthazart, Evrard, Surlemont (1990) Effects of the non-steroidal aromatase inhibitor, R76713 on testosterone-induced sexual behavior in the Japanese quail (Coturnix coturnix japonica). Horm. Behav. 24:510-531.
Balthazart, Foidart, Harada (1990) Immunocytochemical localization of aromatase in the brain. Brain Res. 514:327-333.
Balthazart, Foidart, Hendrick (1990) The induction by testosterone of aromatase activity in the preoptic area and activation of copulatory behavior. Physiol. Behav. 47:83-94.
Balthazart, Foidart, Surlemont, Harada (1990) Preoptic aromatase in quail: behavioral, biochemical and immunocytochemical studies. Hormones, Brain and Behavior in Vertebrates 2. Behavioral Activation in Males and Females — Social Interactions and Reproductive Physiology. Comp. Physiol. , 2nd edn., J. Balthazart, Karger, Basel; 9:45-62.
Balthazart, Foidart, Surlemont, Harada (1991) Neuroanatomical specificity in the co-localization of aromatase and estrogen receptors. J. Neurobiol. 22:143-157.
Balthazart, Foidart, Surlemont, Harada, Leranth, Naftolin (1990) Immunocytochemical localization of aromatase and estrogen receptors in the brain. Soc. Neurosci. 16:1313.
Balthazart, Foidart, Surlemont, Harada, Naftolin (1992) Neuroanatomical specificity in the autoregulation of aromatase-immunoreactive neurons by androgens and estrogens: an immunocytochemical study. Brain Res. 574:280-290.
Balthazart, Foidart, Surlemont, Vockel, Harada (1990) Distribution of aromatase in the brain of the Japanese quail, ring dove, and zebra finch: an immunocytochemical study. J. Comp. Neurol. 301:276-288.
Balthazart, Schumacher, Evrard (1990) Sex differences and steroid control of testosterone-metabolizing enzyme activity in the quail brain. J. Neuroendocrinol. 2:675-683.
Balthazart, Schumacher, Ottinger (1983) Sexual differences in the Japanese quail: behavior, morphology and intracellular metabolism of testosterone. Gen. Comp. Endocrinol. 51:191-207.
Balthazart, Surlemont (1990) Androgen and estrogen action in the preoptic area and activation of copulatory behavior in quail. Physiol. Behav. 48:599-609.
Balthazart, Surlemont (1990) Copulatory behavior is controlled by the sexually dimorphic nucleus of the quail POA. Brain Res. Bull. 25:7-14.
Baum (1992) Neuroendocrinology of sexual behavior in the male. Behavioral Endocrinology , J.B. Becker, S.M. Breedlove, D. Crews, MIT Press, Cambridge, MA, USA; 97-130.
Baylé, Ramade, Oliver (1974) Stereotaxic topography of the brain of the quail. J. Physiol. (Paris) 68:219-241.
Bradford (1976) A rapid sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72:248-254.
Brodie, Wing, Goss, Dowsett, Coombes (1986) Aromatase inhibitors and their potential clinical significance. J. Steroid Biochem. 25:859-865.
Callard, Petro, Ryan (1978) Phylogenetic distribution of aromatase and other androgen-converting enzymes in the central nervous system. Endocrinology 103:2283-2290.
De Coster, Wouters, Bowden, Vanden Bossche, Bruynseels, Tuman, Van Ginckel, Snoeck, Van Peer, Janssen (1990) New non-steroidal aromatase inhibitors: focus on R76713. J. Steroid Biochem. 37:335-341.
Döhler, Hancke, Srivastava, Hofman, Shryne, Gorski (1984) Participation of estrogens in female sexual differentiation of the brain; neuroanatomical, neuroendocrine and behavioral evidence. Prog. Brain Res. 61:99-117.
Harada (1988) Novel properties of human placental aromatase as cytochrome P-450: purification and characterization of a unique form of aromatase. J. Biochem. 103:106-113.
Harada, Abe-Dohmae, Loeffen, Foidart, Balthazart (1993) Synergism between androgens and estrogens in the induction of aromatase and its messenger RNA in the brain. Brain Res. 622:243-256.
Hutchison, Joris, Hutchison, Steimer (1989) Steroid control of sexual behavior and brain aromatase in the dove: effects of nonaromatizable androgens, methyltrienolone (R1881), and 5α-dihydrotestosterone. Horm. Behav. 23:542-555.
Hutchison, Steimer (1986) Formation of behaviorally effective 17β-estradiol in the dove brain: steroid control of preoptic aromatase. Endocrinology 118:2180-2187.
Hutchison (1978) Hormonal differentiation of sexual behavior in Japanese quail. Hom. Behav. 11:363-387.
Jakab, harada, Naftolin (1993) Projective septal neurons are immunoreactive for the estrogen-synthesizing enzyme aromatase. Are there ‘estrogenergic’ neural pathways in the brain?. Soc. Neurosci. Abstr. 19:1442.
Kuenzel, Masson A Stereotaxic Atlas of the Brain of the Chick (Gallus domesticus) , The Johns Hopkins University Press, Baltimore; 1988, 1-166.
Kuenzel, Van Tienhoven (1982) Nomenclature and location of avian hypothalamic nuclei and associated circumventricular organs. J. Comp. Neurol. 206:293-313.
Lephart, Ojeda (1990) Hypothalamic aromatase activity in male and female rats during juvenile peripubertal development. Neuroendocrinology 51:385-393.
MacLusky, Clark, Naftolin, Goldman-Rakic (1987) Estrogen formation in the mammalian brain: possible role of aromatase in sexual differentiation of the hippocampus and neocortex. Steroids 50:459-474.
Maley (1969) Electrical Stimulation of Agonistic Behavior in the Mallard. Behaviour 34:138-160.
Naftolin, Garcia-Segura, Keefe, Leranth, MacLusky, Brawer (1990) Estrogen effects on the synaptology and neural membranes of the rat hypothalamic arcuate nucleus. Biol. Reprod. 42:21-28.
Naftolin, Leranth, Balthazart (1990) Ultrastructural localization of aromatase immunoreactivity in hypothalamic neurons. The Endocrine Soc. Abstr. 669:192.
Naftolin, MacLusky (1984) Aromatization hypothesis revisited. Sexual Differentiation: Basic and Clinical Aspects , M. Serio, M. Motta, M. Zanisi, L. Martini, Raven, New York; 79-91.
Naftolin, MacLusky, Leranth, Sakamoto, Garcia-Segura (1988) The cellular effects of estrogens on neuroendocrine tissues. J. Steroid Biochem. 30:195-207.
Naftolin, Ryan, Davies, Reddy, Flores, Petro, Kuhn, White, Takaoka, Wolin (1975) The formation of estrogens by central neuroendocrine tissues. Rec. Prog. Horm. Res. 31:295-319.
Naftolin, Ryan, Petro (1972) Aromatization of androstenedione by the anterior hypothalamus of adult male and female rats. Endocrinology 90:295-298.
Palkovits (1973) Isolated removal of hypothalamic or other brain nuclei of the rat. Brain Res. 59:449-450.
Palkovits, Brownstein (1983) Microdissection of brain areas by the punch technique. Brain Microdissection Techniques , A.C. Cuello, Wiley, New York; 1-36.
Panzica, Viglietti-Panzica, Sanchez, Sante, Balthazart (1991) Effects of testosterone on a selected neuronal population within the preoptic sexually dimorphic nucleus of the Japanese quail. J. Comp. Neurol. 303:443-456.
Panzica, Viglietti-Panzica, Calcagni, Anselmetti, Schumacher, Balthazart (1987) Sexual differentiation and hormonal control of the sexually dimorphic preoptic medial nucleus in quail. Brain Res. 416:59-68.
Phillips, Youngren (1971) Brain stimulation and species-typical behaviour: activities evoked by electrical stimulation of the brains of chickens (Gallus gallus). Anim. Behav. 19:757-779.
Roselli, Horton, Resko (1985) Distribution and regulation of aromatase activity in the rat hypothalamus and limbic system. Endocrinology 117:2471-2477.
Roselli, Horton, Resko (1987) Time-course and sterood specificity of aromatase indrat hypothalamus-preoptic area. Biol. Reprod. 37:628-633.
Roselli, Resko (1984) Androgens regulate brain aromatase activity in adult male rats through a receptor mechanism. Endocrinology 114:2183-2189.
Roselli, Resko (1989) Testosterone regulates aromatase activity in discrete brain areas of male rhesus macaques. Biol. Reprod. 40:929-934.
Sachs (1967) Photoperiodic control of the cloacal gland of the Japanese quail. Science 157:201-203.
Sachs, Meisel (1988) The physiology of male sexual behavior. The Physiology of Reproduction , E. Knobil, J. Neill et al., Raven, New York; 1393-1485.
Schlinger, Callard (1989) Estrogen receptors in quail brain: a functional relationship to aromatase and aggressiveness. Biol. Reprod. 40:268-275.
Schlinger, Callard (1990) Aromatization mediates agrressive behavior in quail. Gen. Comp. Endocrinol. 79:39-53.
Schumacher, Alexandre, Balthazart (1987) Interactions des androgènes et des oestrogènes dans le contrôle de la reproduction. C.R. Acad. Sci. Paris, Serie III 305:569-574.
Schumacher, Balthazart (1983) The effects of testosterone and its metabolites on sexual behavior and morphology in male and female Japanese quail. Physiol. Behav. 30:335-339.
Schumacher, Balthazart (1984) Sexual dimorphism of the hypothalamic metabolism of testosterone in the Japanese quail (Coturnix coturnix japonica). Prog. Brain Res. 61:53-61.
Schumacher, Balthazart (1984) The postnatal demasculinization of sexual behavior in the Japanese quail. Horm. Behav. 18:298-312.
Schumacher, Balthazart (1987) Neuroanatomical distribution of testosterone metabolizing enzymes in the Japanese quail. Brain Res. 422:137-148.
Schumacher, Contenti, Balthazart (1984) Partial characterization of testosterone-metabolizing enzymes in the quail brain. Brain Res. 305:51-59.
Somogyi, Takagi (1982) A note on the use of picric acid-paraformaldehyde-glutaraldehyde fixative for correlated light and electron microscopic immunocytochemistry. Neuroscience 7:1779-1784.
Steimer, Hutchison (1981) Androgen increases formation of behaviourally effective oestrogen in dove brain. Nature 292:345-347.
Steimer, Hutchison (1980) Aromatization of testosterone within a discrete hypothalamic area associated with the behavioral action of androgen in the male dove. Brain Res. 192:586-591.
Sturkie Avian Physiology , Springer Verlag, New York; 1986, 1-516.
Viglietti-Panzica, Panzica, Fiori, Calcagni, Anselmetti, Balthazart (1986) A sexually dimorphic nucleus in the quail preoptic area. Neurosci. Lett. 64:129-134.
Vockel, Pröve, Balthazart (1990) Effects of castration and testosterone treatment on the activity of testosterone-metabolizing enzymes in the brain of male and female zebra finches. J. Neurobiol. 21:808-825.
Vockel, Pröve, Balthazart (1990) Sex- and age-related difference in the activity of testosterone-metabolizing enzymes in microdissected nuclei of the zebra finch brain. Brain Res. 511:291-302.
Watson, Adkins-Regan (1989) Activation of sexual behavior by implantation of testosterone propionate and estradiol benzoate into the preoptic area of the male Japanese quail (Coturnix japonica). Horm. Behav. 23:251-268.
Watson, Adkins-Regan (1989) Testosterone implanted in the preoptic area of male Japanese quail must be aromatized to activate copulation. Horm. Behav. 23:432-447.
Wouters, De Coster, Krekels, Van Dun, Beerens, Haelterman, Raeymaekers, Freyne, Van Gelder, Venet, Janssen (1989) R 76713, a new specific non-steroidal aromatase inhibitor. J. Steroid Biochem. 32:781-788.
Wouters, De Coster, Tuman, Bowden, Bruynseels, Vanderpas, Van Rooy, Amery, Janssen (1989) Aromatase inhibition by R 76713: experimental and clinical pharmacology. J. Steroid Biochem. 34:427-430.