Article (Scientific journals)
Electrometric assessment of the effect of a zinc oxide paste in diaper dermatitis.
Xhauflaire, Emmanuelle; Henry, Frédérique; Pierard, Claudine et al.
2009In International Journal of Cosmetic Science, 31 (5), p. 369-74
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Abstract :
[en] Diaper dermatitis affects nearly 50% of infants as well as some bed-ridden adults particularly in the elderly people. This condition is induced by irritation and maceration, and may be further exacerbated by Candida sp. colonization and infection. A key factor in the pathogenesis is the alteration in both the barrier function and the water-holding capacity of the stratum corneum. The purpose of this study was to assess the effects of an unmedicated zinc oxide-petrolatum paste and to observe for possible shielding and restoring effects on the water-holding capacity of the stratum corneum altered by diaper dermatitis. The paste appeared to load the hollow skin microrelief. It was inferred that this effect was responsible for a reticulated shielding effect. Compared with healthy skin and untreated diaper dermatitis, the application of the anhydrous paste resulted in a trend to normalize electrometric properties of skin reflecting the combination of transepidermal water loss and the water-holding capacity of the stratum corneum.
Disciplines :
Dermatology
Author, co-author :
Xhauflaire, Emmanuelle ;  Centre Hospitalier Universitaire de Liège - CHU > Dermatopathologie
Henry, Frédérique ;  Centre Hospitalier Universitaire de Liège - CHU > Dermatopathologie
Pierard, Claudine ;  Centre Hospitalier Universitaire de Liège - CHU > Dermatopathologie
Pierard, Gérald ;  Centre Hospitalier Universitaire de Liège - CHU > Dermatopathologie
Language :
English
Title :
Electrometric assessment of the effect of a zinc oxide paste in diaper dermatitis.
Publication date :
2009
Journal title :
International Journal of Cosmetic Science
ISSN :
0142-5463
eISSN :
1467-2494
Publisher :
Blackwell Publishing, United Kingdom
Volume :
31
Issue :
5
Pages :
369-74
Peer reviewed :
Peer Reviewed verified by ORBi
Available on ORBi :
since 10 November 2009

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