Reference : Epstein-Barr virus in Hodgkin's disease: the example of central Tunisia
Scientific journals : Article
Human health sciences : Oncology
http://hdl.handle.net/2268/26899
Epstein-Barr virus in Hodgkin's disease: the example of central Tunisia
French
Korbi, S. [> > > >]
Trimeche, M. [> > > >]
Sriha, B. [> > > >]
Yacoubi, M. T. [> > > >]
Hmissa, S. [> > > >]
Mokni, M. [> > > >]
Delvenne, Philippe mailto [Université de Liège - ULiège > Département des sciences biomédicales et précliniques > Anatomie et cytologie pathologiques >]
Boniver, Jacques mailto [Université de Liège - ULiège > Département des sciences biomédicales et précliniques > Anatomie et cytologie pathologiques]
Rammeh, S. [> > > >]
Apr-2002
Annales de Pathologie
Masson Editeur
22
2
96-101
Yes (verified by ORBi)
International
0242-6498
Paris 06
[en] Epstein-Barr virus ; Hodgkin's disease ; in situ hybridization ; immunohistochemistry
[en] The purpose of this study was to evaluate the prevalence of Epstein-Barr virus in Hodgkin disease in Tunisia through a series of 77 cases. Association with Epstein-Barr virus was demonstrated by Epstein-Barr encoded early RNA transcripts (EBER) in situ hybridization in 70 % of cases and by latent membrane protein I (LMPI) immunohistochemistry in 58.4 % of cases. EBER positive cases were more frequent in extreme age clashes (< 15 and > 54 years) there was no correlation with sex, histologic sub-type and clinical stage. Our findings show a high prevalence for EBV infection in Tunisian Hodgkin's disease particularly among extreme ages.
http://hdl.handle.net/2268/26899

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