Evaluation of hydroxyapatite texture using CTAB template and effects on protein adsorption

[en] This work aims to optimize the texture properties of hydroxyapatite (HA) in view to adopt them as biopharmaceutical drug delivery carrier. For this purpose, cetrimonium bromide (CTAB) has been adopted as a nanotemplate. The micellization behavior of this cationic surfactant has been studied within conditions simulating HA synthesis in order to better understand and control its aggregation behavior during HA synthesis. Micelle formation and their size have been monitored by dynamic light scattering (DLS) in the presence of phosphate ions, adopting different CTAB concentrations. Interestingly, distinct populations of CTAB aggregates have been distinguished in the autocorrelation curves derived from DLS analysis. The influence of CTAB aggregation during HA synthesis has been assessed by comparing the purified inorganic powders by FTIR, XRD, TGA, BET and TEM analysis. The evolution of the size and shape of HA nanoparticles visualized under TEM has been closely correlated to the change in specific surface area, which has considerably increased (up to 150 m2 .g− 1 ) in a narrow range of CTAB concentration. Soybean trypsin inhibitor (STI) was adopted as a model of bone morphogenic protein. Its loading capacity, release rate in vitro and its stability were correlated to the HA nanotexture.

Disciplines :

Materials science & engineering
Biotechnology

Author, co-author :

Monteiro, Ana ; Université de Liège - ULiège > CEIB

Idczak, Gaëlle; Université de Liège - ULiège

Tilkin, Rémi; Centre de recherches Centexbel

Vandeberg, Romain ; Université de Liège - ULiège > CEIB

Vertruyen, Bénédicte ; Université de Liège - ULiège > Département de chimie (sciences) > Chimie inorganique structurale

Lambert, Stéphanie ; Université de Liège - ULiège > Department of Chemical Engineering > Nanomaterials, Catalysis, Electrochemistry

Grandfils, Christian ; Université de Liège - ULiège > Département des sciences biomédicales et précliniques > Biochimie et physiologie générales, et biochimie humaine

Language :

English

Title :

Evaluation of hydroxyapatite texture using CTAB template and effects on protein adsorption

Publication date :

2021

Journal title :

Surfaces and Interfaces

eISSN :

2468-0230

Publisher :

Elsevier, Amsterdam, Netherlands

Volume :

Pages :

101565

Peer reviewed :

Peer Reviewed verified by ORBi

Available on ORBi :

since 19 January 2022

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Bibliography

Arcos, D., Vallet-Regí, M., Substituted hydroxyapatite coatings of bone implants. J. Mater. Chem. B 8 (2020), 1781–1800, 10.1039/c9tb02710f.
Habraken, W., Habibovic, P., Epple, M., Bohner, M., Calcium phosphates in biomedical applications: materials for the future?. Mater. Today 19 (2016), 69–87, 10.1016/j.mattod.2015.10.008.
Lin, K., Xia, L., Gan, J., Zhang, Z., Chen, H., Jiang, X., Chang, J., Tailoring the nanostructured surfaces of hydroxyapatite bioceramics to promote protein adsorption, osteoblast growth, and osteogenic differentiation. ACS Appl. Mater. Interfaces 5 (2013), 8008–8017, 10.1021/am402089w.
Reardon, P.J.T., Huang, J., Tang, J., Morphology controlled porous calcium phosphate nanoplates and nanorods with enhanced protein loading and release functionality. Adv. Healthc. Mater. 2 (2013), 682–686, 10.1002/adhm.201200276.
Zang, S., Chang, S., Shahzad, M.B., Sun, X., Jiang, X., Yang, H., Ceramics-based drug delivery system: a review and outlook. Rev. Adv. Mater. Sci. 58 (2019), 82–97, 10.1515/rams-2019-0010.
Singh, G., Singh, R.P., Jolly, S.S., Customized hydroxyapatites for bone-tissue engineering and drug delivery applications: a review. J. Sol Gel Sci. Technol. 94 (2020), 505–530, 10.1007/s10971-020-05222-1.
Kimura, T., Sugahara, Y., Kuroda, K., Synthesis and characterization of lamellar and hexagonal mesostructured aluminophosphates using alkyltrimethylammonium cations as structure-directing agents. Chem. Mater. 11 (1999), 508–518, 10.1021/cm981036h.
Dimitriou, R., Jones, E., McGonagle, D., Giannoudis, P.V., Bone regeneration: current concepts and future directions. BMC Med., 9, 2011, 66, 10.1186/1741-7015-9-66.
Bialy, I.E., Jiskoot, W., Nejadnik, M.R., Formulation, delivery and stability of bone morphogenetic proteins for effective bone regeneration. Pharm. Res. 34 (2017), 1152–1170, 10.1007/s11095-017-2147-x.
Wang, Q., Wang, M., Lu, X., Wang, K., Fang, L., Ren, F., Lu, G., Effects of atomic-level nano-structured hydroxyapatite on adsorption of bone morphogenetic protein-7 and its derived peptide by computer simulation. Sci. Rep. 7 (2017), 1–14, 10.1038/s41598-017-15219-6.
Huang, B., Lou, Y., Li, T., Lin, Z., Sun, S., Yuan, Y., Liu, C., Gu, Y., Molecular dynamics simulations of adsorption and desorption of bone morphogenetic protein-2 on textured hydroxyapatite surfaces. Acta Biomater. 80 (2018), 121–130, 10.1016/j.actbio.2018.09.019.
Scheufler, C., Sebald, W., Hülsmeyer, M., Crystal structure of human bone morphogenetic protein-2 at 2.7Å resolution. J. Mol. Biol. 287 (1999), 103–115, 10.1006/jmbi.1999.2590.
Reiner, T., Kababya, S., Gotman, I., Protein incorporation within Ti scaffold for bone ingrowth using Sol-gel SiO2 as a slow release carrier. J. Mater. Sci. Mater. Med. 19 (2008), 583–589, 10.1007/s10856-007-3194-3.
Kunitz, M., Crystalline soybean trypsin inhibitor. J. Gen. Physiol. 29 (1946), 149–154, 10.1085/jgp.29.3.149.
Song, H.K., Suh, S.W., Kunitz-type soybean trypsin inhibitor revisited: refined structure of its complex with porcine trypsin reveals an insight into the interaction between a homologous inhibitor from Erythrina Caffra and tissue-type plasminogen activator. J. Mol. Biol. 275 (1998), 347–363, 10.1006/jmbi.1997.1469.
Tilkin, R.G., Colle, X., Argento Finol, A., Régibeau, N., Mahy, J.G., Grandfils, C., Lambert, S.D., Protein encapsulation in functionalized sol-gel silica: effect of the encapsulation method on the release kinetics and the activity. Microporous Mesoporous Mater., 308, 2020, 10.1016/j.micromeso.2020.110502.
Kandori, K.K., Fudo, A., Ishikawa, T., Study on the particle texture dependence of protein adsorption by using synthetic micrometer-sized calcium hydroxyapatite particles. Colloids Surf. B Biointerfaces 24 (2002), 145–153, 10.1016/S0927-7765(01)00227-2.
Nagasaki, T., Nagata, F., Sakurai, M., Kato, K., Effects of pore distribution of hydroxyapatite particles on their protein adsorption behavior. J. Asian Ceram. Soc. 5 (2017), 88–93, 10.1016/j.jascer.2017.01.005.
Kandori, K., Murata, R., Yamaguchi, Y., Yoshioka, A., Protein adsorption behaviors onto Mn (II)-doped calcium hydroxyapatite particles with different morphologies. Colloids Surf. B Biointerfaces 167 (2018), 36–43, 10.1016/j.colsurfb.2018.03.043.
Ma, T., Xia, Z., Liao, L., Effect of reaction systems and surfactant additives on the morphology evolution of hydroxyapatite nanorods obtained via a hydrothermal route. Appl. Surf. Sci. 257 (2011), 4384–4388, 10.1016/j.apsusc.2010.12.067.
Nga, N.K., Giang, L.T., Huy, T.Q., Viet, P.H., Migliaresi, C., Surfactant-assisted size control of hydroxyapatite nanorods for bone tissue engineering. Colloids Surf. B Biointerfaces 116 (2014), 666–673, 10.1016/j.colsurfb.2013.11.001.
Galindo, T.G.P., Yamada, I., Yamada, S., Tagaya, M., Studies on preparation of surfactant-assisted elliptical hydroxyapatite nanoparticles and their protein-interactive ability. Mater. Chem. Phys. 221 (2019), 367–376, 10.1016/j.matchemphys.2018.09.058.
Rajput, S.M., Kuddushi, M., Shah, A., Ray, D., Aswal, V.K., Kailasa, S.K., Malek, N.I., Functionalized surfactant based catanionic vesicles as the soft template for the synthesis of hollow silica nanospheres as new age drug carrier. Surf. Interfaces, 20, 2020, 100596, 10.1016/j.surfin.2020.100596.
Shih, W.J., Wang, M.C., Hon, M.H., Morphology and crystallinity of the nanosized hydroxyapatite synthesized by hydrolysis using cetyltrimethylammonium bromide (CTAB) as a surfactant. J. Cryst. Growth 275 (2005), 2339–2344, 10.1016/j.jcrysgro.2004.11.330.
Khalid, M., Mujahid, M., Amin, S., Rawat, R.S., Nusair, A., Deen, G.R., Effect of surfactant and heat treatment on morphology, surface area and crystallinity in hydroxyapatite nanocrystals. Ceram. Int. 39 (2013), 39–50, 10.1016/j.ceramint.2012.05.090.
Nathanael, A.J., Hong, S.I., Oh, T.H., Seo, Y.H., Singh, D., Han, S.S., Enhanced cell viability of hydroxyapatite nanowires by surfactant mediated synthesis and its growth mechanism. RSC Adv. 6 (2016), 25070–25081, 10.1039/c6ra01155a.
Yang, H., Wang, Y., Morphology control of hydroxyapatite microcrystals: synergistic effects of citrate and CTAB. Mater. Sci. Eng. C 62 (2016), 160–165, 10.1016/j.msec.2016.01.052.
Tilkin, R.G., Mahy, J.G., Régibeau, N., Grandfils, C., Lambert, S.D., Optimization of synthesis parameters for the production of biphasic calcium phosphate ceramics via wet precipitation and sol-gel process. ChemistrySelect 4 (2019), 6634–6641, 10.1002/slct.201901175.
Bennett, G., Lowry's handbook of right-to-know emergency planning. J. Hazard. Mater. 30 (1992), 361–362, 10.1016/0304-3894(92)87011-4.
Cheary, R.W., Coelho, A., A fundamental parameters approach to X-ray line-profile fitting. J. Appl. Crystallogr. 25 (1992), 109–121, 10.1107/S0021889891010804.
Pirard, S.L., Mahy, J.G., Pirard, J.P., Heinrichs, B., Raskinet, L., Lambert, S.D., Development by the sol-gel process of highly dispersed Ni-Cu/SiO2 xerogel catalysts for selective 1,2-dichloroethane hydrodechlorination into ethylene. Microporous Mesoporous Mater. 209 (2015), 197–207, 10.1016/j.micromeso.2014.08.015.
Zhou, T., Han, S., Li, Z., He, P., Purification and quantification of Kunitz trypsin inhibitor in soybean using two-dimensional liquid chromatography. Food Anal. Methods 10 (2017), 3350–3360, 10.1007/s12161-017-0902-6.
Liu, K., Soybean trypsin inhibitor assay: further improvement of the standard method approved and reapproved by American oil chemists’ society and American association of cereal chemists international. JAOCS J. Am. Oil Chem. Soc. 96 (2019), 635–645, 10.1002/aocs.12205.
Tari, N.E., Motlagh, M.M.K., Sohrabi, B., Synthesis of hydroxyapatite particles in catanionic mixed surfactants template. Mater. Chem. Phys. 131 (2011), 132–135, 10.1016/j.matchemphys.2011.07.078.
Gopi, D., Indira, J., Nithiya, S., Kavitha, L., Mudali, U.K., Kanimozhi, K., Influence of surfactant concentration on nanohydroxyapatite growth. Bull. Mater. Sci. 36 (2013), 799–805, 10.1007/s12034-013-0540-6.
Wang, J., Huang, S.P., Hu, K., Zhou, K.C., Sun, H., Effect of cetyltrimethylammonium bromide on morphology and porous structure of mesoporous hydroxyapatite. Trans. Nonferrous Met. Soc. China 25 (2015), 483–489, 10.1016/S1003-6326(15)63628-7 (English Ed.
Goyal, P.S., Dasannacharya, B.A., Kelkar, V.K., Manohar, C., Srinivasa Rao, K., Valaulikar, B.S., Shapes and sizes of micelles in CTAB solutions. Phys. B Phys. Condens. Matter 174 (1991), 196–199, 10.1016/0921-4526(91)90606-F.
Davies, T.S., Ketner, A.M., Raghavan, S.R., Self-assembly of surfactant vesicles that transform into viscoelastic wormlike micelles upon heating. J. Am. Chem. Soc. 128 (2006), 6669–6675, 10.1021/ja060021e.
Patel, V., Dharaiya, N., Ray, D., Aswal, V.K., Bahadur, P., PH controlled size/shape in CTAB micelles with solubilized polar additives: a viscometry, scattering and spectral evaluation. Colloids Surf. A Physicochem. Eng. Asp. 455 (2014), 67–75, 10.1016/j.colsurfa.2014.04.025.
Movchan, T.G., Soboleva, I.V., Plotnikova, E.V., Shchekin, A.K., Rusanov, A.I., Dynamic light scattering study of cetyltrimethylammonium bromide aqueous solutions. Colloid J. 74 (2012), 239–247, 10.1134/S1061933×1202007X.
Goronja, J.M., Ležaić, A.M.J., Dimitrijević, B.M., Malenović, A.M., Stanisavljev, D.R., Pejić, N.D., Određivanje kritične micelarne koncentracije cetiltrimetilamonijum bromida: različite procedure analize eksperimentalnih podataka. Hem. Ind. 70 (2016), 485–492, 10.2298/HEMIND150622055G.
Santos, M.S., Tavares, F.W., Biscaia, E.C., Molecular thermodynamics of micellization: micelle size distributions and geometry transitions. Braz. J. Chem. Eng. 33 (2016), 515–523, 10.1590/0104-6632.20160333s20150129.
Imae, T., Kamiya, R., Ikeda, S., Formation of spherical and rod-like micelles of cetyltrimethylammonium bromide in aqueous NaBr solutions. J. Colloid Interface Sci. 108 (1985), 215–225, 10.1016/0021-9797(85)90253-X.
Ślósarczyk, A., Paluszkiewicz, C., Gawlicki, M., Paszkiewicz, Z., The FTIR spectroscopy and QXRD studies of calcium phosphate based materials produced from the powder precursors with different Ca/P ratios. Ceram. Int. 23 (1997), 297–304, 10.1016/s0272-8842(96)00016-8.
Pattanayak, D.K., Dash, R., Prasad, R.C., Rao, B.T., Rama Mohan, T.R., Synthesis and sintered properties evaluation of calcium phosphate ceramics. Mater. Sci. Eng. C 27 (2007), 684–690, 10.1016/j.msec.2006.06.021.
Panda, R.N., Hsieh, M.F., Chung, R.J., Chin, T.S., FTIR, XRD, SEM and solid state NMR investigations of carbonate-containing hydroxyapatite nano-particles synthesized by hydroxide-gel technique. J. Phys. Chem. Solids 64 (2003), 193–199, 10.1016/S0022-3697(02)00257-3.
Mobasherpour, I., Heshajin, M.S., Kazemzadeh, A., Zakeri, M., Synthesis of nanocrystalline hydroxyapatite by using precipitation method. J. Alloys Compd. 430 (2007), 330–333, 10.1016/j.jallcom.2006.05.018.
Campbell, R.A., Parker, S.R.W., Day, J.P.R., Bain, C.D., External reflection FTIR spectroscopy of the cationic surfactant hexadecyltrimethylammonium bromide (CTAB) on an overflowing cylinder. Langmuir 20 (2004), 8740–8753, 10.1021/la048680x.
Kruk, M., Jaroniec, M., Gas adsorption characterization of ordered organic-inorganic nanocomposite materials. Chem. Mater. 13 (2001), 3169–3183, 10.1021/cm0101069.
Hajimirzaee, S., Chansai, S., Hardacre, C., Banks, C.E., Doyle, A.M., Effects of surfactant on morphology, chemical properties and catalytic activity of hydroxyapatite. J. Solid State Chem. 276 (2019), 345–351, 10.1016/j.jssc.2019.05.031.
Claude, V., Mahy, J.G., Geens, J., Courson, C., Lambert, S.D., Synthesis of Ni/Γ-Al2O3-SiO2 catalysts with different silicon precursors for the steam toluene reforming. Microporous Mesoporous Mater. 284 (2019), 304–315, 10.1016/j.micromeso.2019.04.027.
Yin, G., Liu, Z., Zhan, J., Ding, F., Yuan, N., Impacts of the surface charge property on protein adsorption on hydroxyapatite. Chem. Eng. J. 87 (2002), 181–186, 10.1016/S1385-8947(01)00248-0.
Kandori, K., Masunari, A., Ishikawa, T., Study on adsorption mechanism of proteins onto synthetic calcium hydroxyapatites through ionic concentration measurements. Calcif. Tissue Int. 76 (2005), 194–206, 10.1007/s00223-004-0102-4.
Shen, J.W., Wu, T., Wang, Q., Pan, H.H., Molecular simulation of protein adsorption and desorption on hydroxyapatite surfaces. Biomaterials 29 (2008), 513–532, 10.1016/j.biomaterials.2007.10.016.
Yamada, S., Tagaya, M., Analytical investigation of hydration and protein adsorption structures on hydroxyapatite-based mesoporous silica particles. Mater. Lett. 209 (2017), 441–445, 10.1016/j.matlet.2017.08.072.
Lau, C.C., Reardon, P.J.T., Knowles, J.C., Tang, J., Phase-tunable calcium phosphate biomaterials synthesis and application in protein delivery. ACS Biomater. Sci. Eng. 1 (2015), 947–954, 10.1021/acsbiomaterials.5b00179.
Shen, X., Zhang, Y., Gu, Y., Xu, Y., Liu, Y., Li, B., Chen, L., Sequential and sustained release of SDF-1 and BMP-2 from silk fibroin-nanohydroxyapatite scaffold for the enhancement of bone regeneration. Biomaterials 106 (2016), 205–216, 10.1016/j.biomaterials.2016.08.023.
Brandes, N., Welzel, P.B., Werner, C., Kroh, L.W., Adsorption-induced conformational changes of proteins onto ceramic particles: differential scanning calorimetry and FTIR analysis. J. Colloid Interface Sci. 299 (2006), 56–69, 10.1016/j.jcis.2006.01.065.
Yongli, C., Xiufang, Z., Yandao, G., Nanming, Z., Tingying, Z., Xinqi, S., Conformational changes of fibrinogen adsorption onto hydroxyapatite and titanium oxide nanoparticles. J. Colloid Interface Sci. 214 (1999), 38–45, 10.1006/jcis.1999.6159.