Article (Scientific journals)
THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: G protein-coupled receptors.
Alexander, Stephen Ph; Christopoulos, Arthur; Davenport, Anthony P. et al.
2021In British Journal of Pharmacology, 178 Suppl 1, p. 27-S156
Peer Reviewed verified by ORBi


Full Text
Article_Alexander et al_GPCR guide_2021-2022.pdf
Publisher postprint (1.74 MB)

All documents in ORBi are protected by a user license.

Send to


Keywords :
Databases, Pharmaceutical; Humans; Ion Channels; Ligands; Pharmacology; Receptors, Cytoplasmic and Nuclear; Receptors, G-Protein-Coupled
Abstract :
[en] The Concise Guide to PHARMACOLOGY 2021/22 is the fifth in this series of biennial publications. The Concise Guide provides concise overviews, mostly in tabular format, of the key properties of nearly 1900 human drug targets with an emphasis on selective pharmacology (where available), plus links to the open access knowledgebase source of drug targets and their ligands (, which provides more detailed views of target and ligand properties. Although the Concise Guide constitutes over 500 pages, the material presented is substantially reduced compared to information and links presented on the website. It provides a permanent, citable, point-in-time record that will survive database updates. The full contents of this section can be found at G protein-coupled receptors are one of the six major pharmacological targets into which the Guide is divided, with the others being: ion channels, nuclear hormone receptors, catalytic receptors, enzymes and transporters. These are presented with nomenclature guidance and summary information on the best available pharmacological tools, alongside key references and suggestions for further reading. The landscape format of the Concise Guide is designed to facilitate comparison of related targets from material contemporary to mid-2021, and supersedes data presented in the 2019/20, 2017/18, 2015/16 and 2013/14 Concise Guides and previous Guides to Receptors and Channels. It is produced in close conjunction with the Nomenclature and Standards Committee of the International Union of Basic and Clinical Pharmacology (NC-IUPHAR), therefore, providing official IUPHAR classification and nomenclature for human drug targets, where appropriate.
Disciplines :
Pharmacy, pharmacology & toxicology
Biochemistry, biophysics & molecular biology
Author, co-author :
Alexander, Stephen Ph
Christopoulos, Arthur
Davenport, Anthony P.
Kelly, Eamonn
Mathie, Alistair
Peters, John A.
Veale, Emma L.
Armstrong, Jane F.
Faccenda, Elena
Harding, Simon D.
Pawson, Adam J.
Melmed, Shlomo
Michel, Martin C.
Miller, Laurence J.
Mitolo, Vincenzo
Mouillac, Bernard
Müller, Christa E.
Murphy, Philip
Nahon, Jean-Louis
Ngo, Tony
Norel, Xavier
Southan, Christopher
Nyimanu, Duuamene
O'Carroll, Anne-Marie
Offermanns, Stefan
Panaro, Maria Antonietta
Parmentier, Marc
Pertwee, Roger G.
Pin, Jean-Philippe
Prossnitz, Eric R.
Quinn, Mark
Ramachandran, Rithwik
Davies, Jamie A.
Ray, Manisha
Reinscheid, Rainer K.
Rondard, Philippe
Rovati, G. Enrico
Ruzza, Chiara
Sanger, Gareth J.
Schöneberg, Torsten
Schulte, Gunnar
Schulz, Stefan
Segaloff, Deborah L.
Abbracchio, Maria Pia
Serhan, Charles N.
Stoddart, Leigh A.
Sugimoto, Yukihiko
Summers, Roger
Tan, Valerie P.
Thal, David
Thomas, Walter Wally
Timmermans, Pieter B. M. W. M.
Tirupula, Kalyan
Tulipano, Giovanni
Alexander, Wayne
Unal, Hamiyet
Unger, Thomas
Valant, Celine
Vanderheyden, Patrick
Vaudry, David
Vaudry, Hubert
Vilardaga, Jean-Pierre
Walker, Christopher S.
Wang, Ji Ming
Ward, Donald T.
Al-Hosaini, Khaled
Wester, Hans-Jürgen
Willars, Gary B.
Woodruff, Trent M.
Yao, Chengcan
Ye, Richard D.
Bäck, Magnus
Barnes, Nicholas M.
Bathgate, Ross
Beaulieu, Jean-Martin
Bernstein, Kenneth E.
Bettler, Bernhard
Birdsall, Nigel J. M.
Blaho, Victoria
Boulay, Francois
Bousquet, Corinne
Bräuner-Osborne, Hans
Burnstock, Geoffrey
Caló, Girolamo
Castaño, Justo P.
Catt, Kevin J.
Ceruti, Stefania
Chazot, Paul
Chiang, Nan
Chini, Bice
Chun, Jerold
Cianciulli, Antonia
Civelli, Olivier
Clapp, Lucie H.
Couture, Réjean
Csaba, Zsolt
Dahlgren, Claes
Dent, Gordon
Singh, Khuraijam Dhanachandra
Douglas, Steven D.
Dournaud, Pascal
Eguchi, Satoru
Escher, Emanuel
Filardo, Edward J.
Fong, Tung
Fumagalli, Marta
Gainetdinov, Raul R.
Gasparo, Marc De
Gerard, Craig
Gershengorn, Marvin
Gobeil, Fernand
Goodfriend, Theodore L.
Goudet, Cyril
Gregory, Karen J.
Gundlach, Andrew L.
Hamann, Jörg
Hanson, Julien  ;  Université de Liège - ULiège > Département de pharmacie > Chimie pharmaceutique
Hauger, Richard L.
Hay, Debbie L.
Heinemann, Akos
Hollenberg, Morley D.
Holliday, Nicholas D.
Horiuchi, Mastgugu
Hoyer, Daniel
Hunyady, László
Husain, Ahsan
IJzerman, Adriaan P.
Inagami, Tadashi
Jacobson, Kenneth A.
Jensen, Robert T.
Jockers, Ralf
Jonnalagadda, Deepa
Karnik, Sadashiva
Kaupmann, Klemens
Kemp, Jacqueline
Kennedy, Charles
Kihara, Yasuyuki
Kitazawa, Takio
Kozielewicz, Pawel
Kreienkamp, Hans-Jürgen
Kukkonen, Jyrki P.
Langenhan, Tobias
Leach, Katie
Lecca, Davide
Lee, John D.
Leeman, Susan E.
Leprince, Jérôme
Li, Xaria X.
Williams, Tom Lloyd
Lolait, Stephen J.
Lupp, Amelie
Macrae, Robyn
Maguire, Janet
Mazella, Jean
McArdle, Craig A.
More authors (145 more) Less
Language :
Title :
THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: G protein-coupled receptors.
Publication date :
Journal title :
British Journal of Pharmacology
Publisher :
Wiley-Blackwell, United States
Volume :
178 Suppl 1
Pages :
Peer reviewed :
Peer Reviewed verified by ORBi
Commentary :
© 2021 The Authors. British Journal of Pharmacology published by John Wiley & Sons Ltd on behalf of The British Pharmacological Society.
Available on ORBi :
since 24 November 2021


Number of views
119 (4 by ULiège)
Number of downloads
35 (2 by ULiège)

Scopus citations®
Scopus citations®
without self-citations


Similar publications

Contact ORBi