Article (Scientific journals)
Transcription of the human prolactin gene in mammary cells
Baudhuin, A.; Manfroid, Isabelle; Van de Weerdt, Cécile et al.
2002In Annals of the New York Academy of Sciences, 973, p. 454-458
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Keywords :
prolactin; mammary cells; regulation; Pit-1
Abstract :
[en] Expression of human prolactin in the Mammary gland, one of the main target organs of this hormone, leads to the formation of an autocrine-paracrine proliferative loop in this tissue. Involvement of prolactin in normal and neoplastic mammary development triggered the interest in transcriptional regulation of the human prolactin gene in mammary cells. Analysis of this regulation, and comparison to that in the pituitary, will contribute to a better understanding of mammary gland development and tumor formation. Here we present the first extensive analysis of the transcriptional regulation of the human prolactin gene in human mammary tumor cells.
Disciplines :
Genetics & genetic processes
Author, co-author :
Baudhuin, A.
Manfroid, Isabelle ;  Université de Liège - ULiège > Département des sciences de la vie > Biologie et génétique moléculaire
Van de Weerdt, Cécile ;  Université de Liège - ULiège > Département des sciences de la vie > Biologie et génétique moléculaire
Martial, Joseph ;  Université de Liège - ULiège > Département des sciences de la vie > GIGA-R : Biologie et génétique moléculaire
Muller, Marc  ;  Université de Liège - ULiège > Département des sciences de la vie > Biologie et génétique moléculaire
Language :
English
Title :
Transcription of the human prolactin gene in mammary cells
Publication date :
November 2002
Journal title :
Annals of the New York Academy of Sciences
ISSN :
0077-8923
eISSN :
1749-6632
Publisher :
New York Acad Sciences, New York, United States - New York
Special issue title :
Cell Signaling, Transcription, and Translation As therapeutic Targets
Volume :
973
Pages :
454-458
Peer reviewed :
Peer Reviewed verified by ORBi
Available on ORBi :
since 25 October 2009

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