Abstract :
[en] To understand the abilities of Ca-alginate microcapsules and their specific applications in different fields, it is necessary to
determine the physicochemical and structural properties of those formulated microcapsules. In this work, we aimed to study the
effect of alginate concentration in the improvement of the encapsulation efficiency (EE) and on the release of phenolic and
flavonoid substances. *e relationship between the structure of the encapsulated bioactive substance and Ca-alginate network and
their effect on the EE and release kinetics have been investigated. *e incorporation, structure, morphology, and phase properties
of all elaborated materials were characterized by UV-spectroscopy, Fourier transform infrared (ATR-FTIR), scanning electron
microscope (SEM), and X-ray diffraction (DRX). *e results indicate that increasing the polymer concentration increases the EE
and decreases the loading capacity (LC), whereas the effect of alginate polymer concentration on the release was not observed. *e
release study of bioactive substances showed that the release kinetics is relatively dependent on the structure and the physicochemical characteristics of the bioactive substance, which became clear when the encapsulated compounds were released from
the core of calcium alginate microcapsules. *us, it could be concluded that the pores size of the Ca-alginate network is smaller
than the volume of the crocin molecule (2794.926A˚ 3
) and higher than the volume of the gallic acid molecule (527.659A˚ 3
). For the
same microcapsules system, the release mechanism is affected by the structure and physicochemical properties of the
encapsulated molecules.
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