[en] This study focuses on the controversy surrounding selective approaches to screen for osteoporosis. Seven screening approaches were compared in terms of cost-effectiveness and incremental cost-effectiveness ratios in a sample of 4035 postmenopausal women. Our results show that certain prescreening strategies are more efficient than DXA-based approaches. These results are of considerable value for health policy decision-makers and the scientific community.
Disciplines :
Endocrinology, metabolism & nutrition
Author, co-author :
Richy, F.
Ethgen, Olivier ; Université de Liège - ULiège > Département des sciences de la santé publique > Santé publique : aspects spécifiques
Bruyère, Olivier ; Université de Liège - ULiège > Département des sciences de la santé publique > Epidémiologie et santé publique
Gillet P, Reginster JY 1999 Increased number of hip fractures. Lancet 353:2160-2161.
Nelson HD, Helfand M, Woolf SH, Allan JD 2002 Screening for postmenopausal osteoporosis: A review of the evidence for the U.S. Preventive Services Task Force. Ann Intern Med 137:529-541.
National Osteoporosis Foundation 2003 Physician's guide to prevention and treatment of osteoporosis 2003. Available online at http://www.nof.org/. Accessed May 20, 2004.
Anonymous 2000 A decision tree for the use of estrogen replacement therapy or hormone replacement therapy in postmenopausal women: Consensus opinion of the North American Menopause Society. Menopause 7:76-86.
Anonymous 2000 Osteoporosis prevention, diagnosis and therapy. NIH Consens State Sci Statements 17:1-45
Genant HK, Cooper C, Poor G, Reid I, Ehrlich G, Kanis J, Nordin BE, Barrett-Connor E, Black D, Bonjour JP, Dawson-Hughes B, Delmas PD, Dequeker J, Ragi Eis S, Gennari C, Johnell O, Johnston CC, Lau EM, Liberman UA, Lindsay R, Martin TJ, Masri B, Mautalen CA, Meunier PJ, Khaltaev N 1999 Interim report and recommendations of the World Health Organization Task-Force for Osteoporosis. Osteoporos Int 10:259-264.
Cadarette S, Jaglal S, Kreiger N, McIsaac W, Darlington G, Tu J 2000 Development and validation of the osteoporosis risk assessment instrument to facilitate selection of women for bone densitometry. Can Med Assoc J 162:1289-1294.
Lydick E, Cook K, Turpin J, Melton M, Stine R, Byrnes C 1998 Development and validation of a simple questionnaire to facilitate identification of women likely to have low bone density. Am J Manage Care 4:37-48.
Van der Voort DJM, Dinant GJ, Rinkens PELM, van der Voort-Duindam CJM, van Wersch JWJ, Geusens PP 2000 Construction of an algorithm for quick detection of patients with low bone mineral density and its applicability in daily general practice. J Clin Epidemiol 53:1095-1103.
Weinstein L, Ullery B, Bourguignon C 1999 A simple system to determine who needs osteoporosis screening. Obstet Gynecol 93:757-760.
Von Mühlen D, Visby Lunde A, Barrett-Connor E, Bettencourt R 1999 Evaluation of the simple calculated osteoporosis risk estimation (SCORE) in older Caucasian women: The Rancho Bernardo Study. Osteoporos Int 10:79-84.
Cadarette S, Jaglal S, Murray T 1999 Validation of the simple calculated osteoporosis risk estimation (SCORE) for patient selection for bone densitometry. Osteoporos Int 10:85-90.
Koh LK, Sedrine WB, Torralba TP, Kung A, Fujiwara S, Chan SP, Huan QR, Rajatanavin R, Tsai KS, Park HM, Reginster JY 2001 A simple tool to identify asian women at increased risk of osteoporosis. Osteoporos Int 12:699-705.
Sedrine WB, Chevalier T, Zegels B, Kvasz A, Micheletti MC, Gelas B, Reginster JY 2002 Development and assessment of the Osteoporosis Index of Risk (OSIRIS) to facilitate selection of women for bone densitometry. Gynecol Endocrinol 16:245-250.
Richy F, Gourlay M, Ross PD, Sen SS, Radican L, De Ceulaer F, Ben Sedrine W, Ethgen O, Bruyere O, Reginster JY 2004 Validation and comparative evaluation of the osteoporosis self-assessment Tool (OST) in a Caucasian Population from Belgium. QJM 97:39-46.
Reginster JY, Janssen C, Deroisy R, Zegels B, Albert A, Franchimont P 1995 Bone mineral density of the spine and the hip measured with dual energy X-ray absorptiometry: Normal range and fracture threshold for western European (Belgian) postmenopausal females. Clin Rheumatol 14:68-75.
Reginster JY, Deroisy R, Lecart MP, Franchimont P 1996 Prévention de l'Ostéoporose à Liège. Histoire d'un PIGEPS: Dix ans après. Santé Publique 2:139-150.
Kanis JA, Johnell O, Oden, A, Dawson A, De Laet C, Jonsson B 2001 Ten years probabilities of osteoporotic fractures according to BMD and diagnostic thresholds. Osteoporos Int 12:989-995
Anastasopoulou C, Rude RK 2002 Bone mineral density screening: Assessment of influence on prevention and treatment of osteoporosis. Endocr Pract 8:199-201.
Ben Sedrine W, Broers P, Devogelaer JP, Depresseux G, Kaufman JM, Goemaere S, Sedrine WB, Chevallier T, Zegels B, Kvasz A, Micheletti MC, Gelas B, Reginster JY 2002 Interest of a prescreening questionnaire to reduce the cost of bone densitometry. Osteoporos Int 13:434-442.
Kanis JA, Johnell O, Oden A, Jonsson B, De Laet C, Dawson A 2000 Prediction of fracture from low bone mineral density measurements overestimates risk. Bone 26:387-391.
Felson DT, Zhang Y, Hannan MT, Kiel DP, Wilson PW, Anderson JJ 1993 The effect of postmenopausal estrogen therapy on bone density in elderly women. N Engl J Med 329:1141-1146.
Cummings SR, Black DM, Thompson DE, Applegate WB, Barrett-Connor E, Musliner TA, Palermo L, Prineas R, Rubin SM, Scott JC, Vogt T, Wallace R, Yates AJ, LaCroix AZ 1998 Effect of alendronate on risk of fracture in women with low bone mineral density but without fractures. JAMA 280:2077-2082.
Van Oyen H, Tafforeau J, Hermans H, Quataert P, Schiettecatte E, Lebrun L, Bellamammer L 1997 The Belgian Health Interview Survey. Arch Public Health 55:1-13.