Article (Scientific journals)
Early inflammation in the airways of a cystic fibrosis foetus
Verhaeghe, C.; Delbecque, Katty; de Leval, Laurence et al.
2007In Journal of Cystic Fibrosis, 6 (4), p. 304-308
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Keywords :
CFTR; NF-kappa B; pro-inflammatory cytokines
Abstract :
[en] In cystic fibrosis patients, inflammation is often considered to be secondary to chronic infections. In the present study, we show increased levels of pro-inflammatory proteins in the lungs of a cystic fibrosis foetus compared to the lungs of two normal foetuses. Our findings suggest therefore the existence of an early intrinsic pro-inflammatory state in cystic fibrosis airways. (C) 2006 European Cystic Fibrosis Society. Published by Elsevier B.V. All rights reserved.
Disciplines :
Cardiovascular & respiratory systems
Author, co-author :
Verhaeghe, C.
Delbecque, Katty ;  Centre Hospitalier Universitaire de Liège - CHU > Anatomie pathologique
de Leval, Laurence ;  Université de Liège - ULiège > Département des sciences biomédicales et précliniques > Anatomie et cytologie pathologiques
Oury, Cécile  ;  Université de Liège - ULiège > Département des sciences biomédicales et précliniques > Génétique générale et humaine
Bours, Vincent ;  Université de Liège - ULiège > Département des sciences biomédicales et précliniques > Génétique générale et humaine
Language :
English
Title :
Early inflammation in the airways of a cystic fibrosis foetus
Publication date :
July 2007
Journal title :
Journal of Cystic Fibrosis
ISSN :
1569-1993
eISSN :
1873-5010
Publisher :
Elsevier Science Bv, Amsterdam, Netherlands
Volume :
6
Issue :
4
Pages :
304-308
Peer reviewed :
Peer Reviewed verified by ORBi
Available on ORBi :
since 23 October 2009

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