Chen, Q.; College of Biological Science and Engineering, Beijing University of Agriculture, No. 7 Beinong Road, Haidian District, Beijing, 102206, China, Key Laboratory of Urban Agriculture (North China), Ministry of Agriculture, No. 7 Beinong Road, Haidian District, Beijing, 102206, China
Xin, T.; Department of Veterinary Medicine, Institute of Animal Sciences, Chinese Academy of Agricultural Sciences, No. 2 Yuanmingyuan West Road, Haidian District, Beijing, 100193, China
Sun, Y.; China Animal Husbandry Industry Co., Ltd, No. 6 Huansan Road, Fengtai District, Beijing, 100070, China
Jia, H.; Department of Veterinary Medicine, Institute of Animal Sciences, Chinese Academy of Agricultural Sciences, No. 2 Yuanmingyuan West Road, Haidian District, Beijing, 100193, China
Hou, S. H.; Department of Veterinary Medicine, Institute of Animal Sciences, Chinese Academy of Agricultural Sciences, No. 2 Yuanmingyuan West Road, Haidian District, Beijing, 100193, China
Guo, X. Y.; Department of Veterinary Medicine, Institute of Animal Sciences, Chinese Academy of Agricultural Sciences, No. 2 Yuanmingyuan West Road, Haidian District, Beijing, 100193, China
PUC18-CpG stimulates RAW 264.7 via TBK1-mediated pathway and presents adjuvanticity in mice
Bahia D, Satoskar AR, Dussurget O (2018) Editorial: Cell Signaling in Host-Pathogen Interactions: The Host Point of View. Front Immuno 9: 221.
Dempsey A, Bowie AG (2015) Innate immune recognition of DNA: a recent history. Virology 479-480: 146-152.
Guo X, Jia H, Yuan W, Zhang Q, Hou S, Sun Y, Zhu G, Zhu H, Sánchez-Vizcaíno JM (2012) Construction of swine-specific CpG motif enriched plasmid and the study of its immunostimulatory effects both in vitro and in vivo. J Vet Med Sci 74: 1647-1650.
Guo X, Zhang Q, Hou S, Zhai G, Zhu H, Sánchez-Vizcaíno JM (2011) Plasmid containing CpG motifs enhances the efficacy of porcine reproductive and respiratory syndrome live attenuated vaccine. Vet Immunol Immunopathol 144: 405-409.
He Z, Xu J, Tao W, Fu T, He F, Hu R, Jia L, Hong Y (2016) A recombinant plasmid containing CpG motifs as a novel vaccine adjuvant for immune protection against herpes simplex virus 2. Mol Med Rep 14: 1823-1828.
Heath DD, Koolaard J (2012) Serological monitoring of protection of sheep against Echinococcus granulosus induced by the EG95 vaccine. Parasite Immunol 34: 40-44.
Heath DD, Robinson C, Shakes T, Huang Y, Gulnur T, Shi B, Zhang Z, Anderson GA, Lightowlers MW (2012) Vaccination of bovines against Echinococcus granulosus (cystic echinococcosis). Vaccine 30: 3076-3081.
Hemmi H, Takeuchi O, Kawai T, Kaisho T, Sato S, Sanjo H, Matsumoto M, Hoshino K, Wagner H, Takeda K, Akira S (2000) A Toll-like receptor recognizes bacterial DNA. Nature 408: 740-745.
Ishii KJ, Kawagoe T, Koyama S, Matsui K, Kumar H, Kawai T, Uematsu S, Takeuchi O, Takeshita F, Coban C, Akira S (2008) TANK-binding kinase-1 delineates innate and adaptive immune responses to DNA vaccines. Nature 451: 725-729.
Janeway CA Jr, Medzhitov R (2002) Innate immune recognition. Annu Rev Immunol 20: 197-216.
Kumagai Y, Takeuchi O, Akira S (2008) TLR9 as a key receptor for the recognition of DNA. Adv Drug Deliv Rev 60: 795-804.
Lange MJ, Burke DH, Chaput JC (2018) Activation of innate immune responses by a CpG oligonucleotide sequence composed entirely of threose nucleic acid. Nucleic Acids Res doi: 10.1089/nat.2018.0751.
Li XD, Wu J, Gao D, Wang H, Sun L, Chen ZJ (2013) Pivotal roles of cGAS-cGAMP signaling in antiviral defense and immune adjuvant effects. Science 341: 1390-1394.
Livak KJ, Schmittgen TD (2001) Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods 25: 402-408.
Luo Z, Shi H, Zhang H, Li M, Zhao Y, Zhang J, Guo F, Luo S, Sun P, Zhang D, Qian Z, Yang L (2012) Plasmid DNA containing multiple CpG motifs triggers a strong immune response to hepatitis B surface antigen when combined with incomplete Freund's adjuvant but not aluminum hydroxide. Mol Med Rep 6: 1309-1314.
Medzhitov R (2009) Approaching the asymptote: 20 years later. Immunity 30: 766-775.
Paludan SR (2015) Activation and regulation of DNA-driven immune responses. Microbiol Mol Biol Rev 79: 225-241.
Poggio TV, Jensen O, Mossello M, Iriarte J, Avila HG, Gertiser ML, Serafino JJ, Romero S, Echenique MA, Dominguez DE, Barrios JR, Heath D (2016) Serology and longevity of immunity against Echinococcus granulosus in sheep and llama induced by an oil-based EG95 vaccine. Parasite Immunol 38: 496-502.
Scheiermann J, Klinman DM (2014) Clinical evaluation of CpG oligonucleotides as adjuvants for vaccines targe-ting infectious diseases and cancer. Vaccine 32: 6377-6389.
Shirota H, Klinman DM (2014) Recent progress concerning CpG DNA and its use as a vaccine adjuvant. Expert Rev Vaccines 13: 299-312.
Sun L, Wu J, Du F, Chen X, Chen ZJ (2013) Cyclic GMP-AMP synthase is a cytosolic DNA sensor that activates the type I interferon pathway. Science 339: 786-791.
Takeuchi O, Akira S (2010) Pattern recognition receptors and inflammation. Cell 140: 805-820.
Tao J, Zhou X, Jiang Z (2016) cGAS-cGAMP-STING: The three musketeers of cytosolic DNA sensing and signaling. IUBMB Life 68: 858-870.
Umair S, Pernthaner A, Deng Q, Gibson B, Hook S, Heath D (2017) Preliminary evaluation of a thermosensitive chitosan hydrogel for Echinococcus granulosus vaccine delivery. Vet Parasitol 236: 117-120.
Wu J, Chen ZJ (2014) Innate immune sensing and signaling of cytosolic nucleic acids. Annu Rev Immunol 32: 461-488.