Reference : Catecholaminergic function and P300 amplitude in major depressive disorder (P300 and ...
Scientific journals : Article
Social & behavioral sciences, psychology : Neurosciences & behavior
http://hdl.handle.net/2268/26163
Catecholaminergic function and P300 amplitude in major depressive disorder (P300 and catecholamines).
English
Hansenne, Michel mailto [Université de Liège - ULiège > Département des sciences cognitives > Psycho. de la personnalité et des différences individuelles >]
Pitchot, William mailto [Centre Hospitalier Universitaire de Liège - CHU > > Psychiatrie et psychologie médicale >]
Gonzalez Moreno, Antonio [> > > >]
Papart, Patrick mailto [Centre Hospitalier Universitaire de Liège - CHU > > Psychiatrie et psychologie médicale >]
Timsit-Berthier, Martine [> > > >]
Ansseau, Marc mailto [Centre Hospitalier Universitaire de Liège - CHU > > Psychiatrie et psychologie médicale >]
1995
Electroencephalography and Clinical Neurophysiology
Elsevier
96
2
194-6
Yes (verified by ORBi)
International
0013-4694
Limerick
Ireland
[en] Adult ; Apomorphine/diagnostic use ; Brain/physiopathology ; Catecholamines/physiology ; Clonidine/diagnostic use ; Depressive Disorder/blood/physiopathology ; Electroencephalography ; Female ; Growth Hormone/blood ; Humans ; Male ; Middle Aged
[en] The neurobiology of P300 is still a subject of controversy. P300 amplitude appears to be modulated by multiple neurotransmitter systems, especially dopaminergic, noradrenergic as well as cholinergic and GABAergic. In this study, we investigated the relationship between P300 amplitude and catecholaminergic neurotransmission as assessed by the growth hormone (GH) response to clonidine and apomorphine challenges in 20 major depressive patients. Results showed a correlation of P300 amplitude with the apomorphine test (r = 0.54; P = 0.01), but not with the clonidine test (r = 0.22; NS). This study supports a role for dopamine in the neurobiological modulation of P300 amplitude.
Centre de Neurosciences Cognitives et Comportementales
http://hdl.handle.net/2268/26163
also: http://hdl.handle.net/2268/87842
10.1016/0168-5597(94)00317-8

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