[en] Background: In recent years there have been significant advancements in the understanding of mineral oil hydrocarbons
(MOH) in foods and their potential risk to health. However, important gaps in knowledge remain,
such as the lack of validated and standardized analytical methods for relevant food matrices and gaps in assessing
the risk for consumers’ health.
Scope & approach: A workshop was organized by the European Branch of the International Life Science Institute
to identify knowledge gaps in analytical methods, assessment of exposure, hazard characterisation, and risk
assessment of MOH. This work captures the outcome of the workshop and builds upon it by combining the
perspectives of the participants with an updated review of the literature to provide a roadmap for future management
of the topic.
Key findings and conclusions: Most participants to the workshop agreed that the key issue underlying many of the
knowledge gaps in the field of MOH risk analysis and management is the lack of standardized, validated
analytical methods able to assure good inter-laboratory reproducibility and to enable understanding of MOH
occurrence in foods. It has been demonstrated that method EN 16995 used for MOH determination in vegetable
oils and fats is not reliable below 10 mg/kg of food. There is also a need for confirmatory methods that provide a
detailed characterization of the unresolved complex mixture observed from one-dimensional chromatographic
methods. This is required to enable adequate substance identification and quantification for input into risk
assessment. A major gap in the exposure estimation is the limited number of surveys covering a wide range of
foods and enough samples to detect major sources of contamination other than packaging in paperboard. Data on
concentration of MOH fractions in human body needed to determine internal exposure estimates is scarce. Data
relating concentration in tissues with personal data, lifestyle, food intake and the use of cosmetics are needed to
clarify the complex system of distribution of MOSH in the body and to possibly establish relationship between
external and internal exposure. Additional toxicological studies to better characterize the hazards of relevant
MOH are required for a better human health risk assessment.
Disciplines :
Life sciences: Multidisciplinary, general & others Chemistry Food science Pharmacy, pharmacology & toxicology
Author, co-author :
Hochegger, Andrea; Karl-Franzens-Universität (Graz) > Institute of Analytical Chemistry and Food Chemistry
Moret, Sabrina; Università degli Studi di Udine-UniUD > Department of Agri-Food, Environmental and Animal Sciences
Geurts, Lucie; ILSI Europe
Gude, Thomas; Swiss Quality Testing
Leitner, Eric; Karl-Franzens-Universität (Graz)
Mertens, Birgit; Sciensano
O'Hagan, Susan; PepsiCo
Poças, Fatima; Universidade Catolica Portuguesa > CBQF - Centro de Biotecnologia e Química Fina
Simat, Thomas; Technical University Dresden,
Purcaro, Giorgia ; Université de Liège - ULiège > Département GxABT > Chimie des agro-biosystèmes
Language :
English
Title :
Mineral oil risk assessment: Knowledge gaps and roadmap. Outcome of a multi-stakeholders workshop
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