Milnacipran in obsessive-compulsive disorder: Study in one case

Obsessive-compulsive disorder is a severe pathology which is difficult to treat. Several recent studies have shown the efficacy of some antidepressants, particularly of the serotonergic type. Other findings, however, suggest a role for the noradrenergic neurotransmission. We present a trial using a new antidepressant, milnacipran, with both noradrenergic and serotonergic activity, in a patient presenting treatment-resistant obessive compulsive disorders. The role of the drug in the marked improvement of the patient's symptomatology is discussed.