Neurohypophyseal Peptides and Psychopathology

[en] The study of neurohypophyseal peptides in various neuropsychiatric disorders is of interest because the hypothalamo-posterior pituitary axis is directly influenced by modifications of central neurotransmitter metabolism involved in behaviour control. Moreover, the main neurohypophyseal peptides, namely vasopressin and oxytocin, are themselves capable of modifying behaviour. In this paper the author discusses current understanding of the anatomy and physiology of the main central vasopressinergic and oxytocinergic pathways. followed by a description of the principal actions of exogenously administered vasopressin and oxytocin on human behaviour. Finally, modifications of endogenous neurohypophyseal function encountered in different pathological states are described.

Disciplines :

Treatment & clinical psychology

Author, co-author :

Legros, Jean-Jacques ; Université de Liège - ULiège > Département des sciences cliniques > Département des sciences cliniques

Ansseau, Marc ; Université de Liège - ULiège > Département des sciences cliniques > Psychiatrie et psychologie médicale

Language :

English

Title :

Neurohypophyseal Peptides and Psychopathology

Publication date :

1992

Journal title :

Progress in Brain Research

ISSN :

0079-6123

eISSN :

1875-7855

Publisher :

Elsevier, Netherlands

Volume :

Pages :

455-460, discussion 461

Peer reviewed :

Peer Reviewed verified by ORBi

Available on ORBi :

since 23 April 2021

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Bibliography

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