Pharmacogenetics of infliximab in Crohn's disease

Dideberg, Vinciane; Louis, Edouard; Bours, Vincent

doi:10.1007/BF02961799

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Pharmacogenetics of infliximab in Crohn's disease

Dideberg, Vinciane; Louis, Edouard; Bours, Vincent

2007 • In Acta Endoscopica, 37 (4), p. 521-530

Peer reviewed

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https://hdl.handle.net/2268/25881

DOI
10.1007/BF02961799

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Keywords :

Crohn's disease; infliximab; pharmacogenetics

Abstract :

[en] Pharmacogenetic studies will certainly contribute to a better management of medication in inflammatory bowel diseases. Infliximab is the most efficient drug in refractory and fistulising Crohn's disease. However, about one third of the patients do not respond to this treatment. Several studies have been performed to identify predictive factors of the response to infliximab in CD. We attempt to summarize the current knowledge on the use of infliximab in CD and focus on the result of these studies and more particularly on pharmacogenetic aspects.

Disciplines :

Surgery

Author, co-author :

Dideberg, Vinciane ; Centre Hospitalier Universitaire de Liège - CHU > Génétique

Louis, Edouard ; Université de Liège - ULiège > Département des sciences cliniques > Hépato-gastroentérologie

Bours, Vincent ; Université de Liège - ULiège > Département des sciences biomédicales et précliniques > Génétique générale et humaine

Language :

English

Title :

Pharmacogenetics of infliximab in Crohn's disease

Publication date :

2007

Journal title :

Acta Endoscopica

ISSN :

0240-642X

eISSN :

1242-1383

Publisher :

Endoscopica, Nancy, Belgium

Volume :

Issue :

Pages :

521-530

Peer reviewed :

Peer reviewed

Available on ORBi :

since 19 October 2009

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