[en] Equine atypical myopathy (AM) is seasonal intoxication resulting from the ingestion of seeds and seedlings of the sycamore maple (Acer pseudoplatanus) that contain toxins, among them, hypoglycin A (HGA). Literature mentions several cases of AM among gravid mares and in unweaned foals. The objective of this study was to determine whether HGA and/or its metabolite are present in milk from grazing mares exposed to sycamore maple trees as confirmed by detection of HGA and its metabolite in their blood. Four mare/foal couples were included in the study. Both HGA and its metabolite were detectable in all but one of the milk samples. To our knowledge, this is the first study describing transfer of HGA to the milk. This unprecedented observation could partially explain cases of unweaned foals suffering from AM. However, a transplacental transfer of the toxin cannot be excluded for newborn foals. Besides being a source of contamination for offspring, milk contamination by toxins from fruits of trees of the Sapindaceae family might constitute a potential risk for food safety regarding other species' raw milk or dairy products.
Centre/Unité de recherche :
FARAH - Fundamental and Applied Research for Animals and Health - ULiège
Disciplines :
Médecine vétérinaire & santé animale
Auteur, co-auteur :
Renaud, Benoît ; Université de Liège - ULiège > Département des sciences fonctionnelles (DSF) > Département des sciences fonctionnelles (DSF)
François, Anne-Christine ; Université de Liège - ULiège > Pharmacologie, pharmacothérapie et toxicologie
Boemer, François ; Université de Liège - ULiège > Département de pharmacie > Chimie médicale
Kruse, Caroline ; Université de Liège - ULiège > Département des sciences fonctionnelles (DSF) > Phys. neuro-muscul., de l'effort - Méd. sport. des animaux
Stern, David ; Université de Liège - ULiège > Scientifiques attachés au Doyen (F MV)
PIOT, Amandine ; Centre Hospitalier Universitaire de Liège - CHU > > Service de génétique
Petitjean, Thierry; Arsia asbl [BE]
Gustin, Pascal ; Université de Liège - ULiège > Département des sciences fonctionnelles (DSF) > Pharmacologie, pharmacothérapie et toxicologie
Votion, Dominique ; Université de Liège - ULiège > Scientifiques attachés au Doyen (F MV)
Langue du document :
Anglais
Titre :
Grazing Mares on Pasture with Sycamore Maples: A Potential Threat to Suckling Foals and Food Safety through Milk Contamination.
Titre traduit :
[fr] Une menace potentielle pour les poulains de lait et la sécurité alimentaire par la contamination du lait avec les juments au pâturage avec des érables sycomores
Date de publication/diffusion :
2021
Titre du périodique :
Animals
ISSN :
2076-2615
eISSN :
2076-2615
Maison d'édition :
MDPI
Volume/Tome :
11
Fascicule/Saison :
1
Peer reviewed :
Peer reviewed
Intitulé du projet de recherche :
SAMA
Organisme subsidiant :
SPW Agriculture, Ressources naturelles et Environnement - Service Public de Wallonie. Agriculture, Ressources naturelles et Environnement [BE]
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