Keywords :
Acetaminophen/pharmacokinetics/poisoning; Analgesics, Non-Narcotic/pharmacokinetics/poisoning; Antidotes/therapeutic use; Humans; Poisoning/diagnosis/epidemiology/therapy; Practice Guidelines as Topic
Abstract :
[en] Drug self-poisoning is a common cause of admission in ED. Among various incriminated substances, paracetamol is often implicated and presents a severe toxicity. We briefly describe the epidemiology and physiopathology of paracetamol self-poisoning. We then clarify the diagnostic elements, thresholds of toxicity, indications for treatment and different available therapeutic guidelines.
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