Article (Scientific journals)
Pre-Operative Ability of Clinical Scores to Predict Obstructive Sleep Apnea (OSA) Severity in Susceptible Surgical Patients.
Deflandre, Eric; Degey, S.; Brichant, Jean-François et al.
2016In Obesity Surgery
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Keywords :
Mass screening; Obesity; Obstructive; Perioperative period; Postoperative complications; Sleep apnea
Abstract :
[en] BACKGROUND: Severe obstructive sleep apnea (OSA) is an independent risk factor for perioperative complications. Clinical scores such as Snoring, Tiredness, Observed apnea, high blood Pressure, Body Mass Index (BMI) higher than 35 kg m-2, Age older than 50 years, Neck circumference larger than 40 cm, and male gender (STOP-Bang), perioperative sleep apnea prediction (P-SAP), and OSA50 have been proposed for detecting OSA. We recently proposed a new score based on morphological metrics only, the DES-OSA score. This study compared the DES-OSA score to the three other ones with regard to their ability to detect OSA. Obese patients are particularly at risk of OSA. METHODS: Following informed consent and institutional review board (IRB) approval, 1584 consecutive adults were. Should the STOP-Bang be indicative of increased risk of severe OSA, the patient was referred to complementary polysomnography (PSG). Eventual already existing recent PSG data were also collected. The abilities of the four scores to predict OSA severity were compared using sensitivity, specificity, Cohen's kappa coefficient (CKC), and area under ROC curve (AUROC) analysis. RESULTS: PSG was performed in 150 patients. For detecting severe OSA, OSA50 had the highest sensitivity [value (95 % CI) 0.98 (0.90-1)]. STOP-Bang was significantly less sensitive than P-SAP and OSA50. In that respect, DES-OSA was significantly more specific than the three other ones [0.75 (0.65-0.83)]. The AUROC of DES-OSA was significantly the largest [0.9 (0.84-0.95)]. The highest CKC at detecting severe OSA was 0.62 (0.49-0.74) for DES-OSA. Similar results were obtained for moderate to severe OSA prediction. CONCLUSIONS: DES-OSA, which is the only exclusively morphological score available, appears to surpass the three other scores in their ability to predict moderate to severe and severe OSA, at least in our setting and in our screened population. CLINICAL TRIAL REGISTRATION: ClinicalTrial.gov NCT02051829.
Disciplines :
Anesthesia & intensive care
Author, co-author :
Deflandre, Eric 
Degey, S.
Brichant, Jean-François ;  Université de Liège > Département des sciences cliniques > Anesthésie et réanimation
Donneau, Anne-Françoise ;  Université de Liège > Département des sciences de la santé publique > Biostatistique
Frognier, R.
Poirrier, Robert ;  Université de Liège > Département des sciences cliniques > Département des sciences cliniques
BONHOMME, Vincent  
Language :
English
Title :
Pre-Operative Ability of Clinical Scores to Predict Obstructive Sleep Apnea (OSA) Severity in Susceptible Surgical Patients.
Publication date :
2016
Journal title :
Obesity Surgery
ISSN :
0960-8923
eISSN :
1708-0428
Publisher :
Springer, United States - New York
Peer reviewed :
Peer Reviewed verified by ORBi
Available on ORBi :
since 26 December 2020

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