Article (Scientific journals)
Adrenal Ganglioneuroma. A Neoplasia to Exclude in Patients with Adrenal Incidentaloma
Maweja, Sylvie; Materne, R.; Detrembleur, Nancy et al.
2007In Acta Chirurgica Belgica, 107 (6, Nov-Dec), p. 670-4
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Abstract :
[en] OBJECTIVE: To determinate the MRI and CT scanning appearance of adrenal ganglioneuroma and correlate the imaging with histological features. SUMMARY BACKGROUND DATA: In the last 10 years, eight patients with a pathologically proven adrenal ganglioneuroma were operated on in our department of endocrine surgery. To our knowledge, these patients represent one the largest reported cohorts of adrenal ganglioneuroma treated in a single institution. METHODS: All these eight patients had a comprehensive hormonal work up and underwent CT and/or MRI. Biological data, radiological features and histological findings were thoroughly reviewed in order to further characterize these tumours. RESULTS: The most relevant characteristics of adrenal GN resected in our patients were: No hormonal hypersecretion, Presence of calcifications; no vessel involvement; and a non-enhanced attenuation of less than 40 HU on CT, A low non-enhanced T1W signal, a slightly high and heterogeneous T2W signal, a late and gradual enhancement on dynamic MRI, especially if associated with a whorled pattern. CONCLUSIONS: Even if many aggressive tumours, mainly adrenal carcinoma, may share some of these radiological features, the presence of all or most of them must made the clinician evoke the diagnosis of GN.
Disciplines :
Oncology
Author, co-author :
Maweja, Sylvie ;  Centre Hospitalier Universitaire de Liège - CHU > Chirurgie abdominale- endocrinienne et de transplantation
Materne, R.
Detrembleur, Nancy ;  Centre Hospitalier Universitaire de Liège - CHU > Anatomie pathologique
de Leval, Laurence ;  Université de Liège - ULiège > Département des sciences biomédicales et précliniques > Anatomie et cytologie pathologiques
Defechereux, Thierry ;  Centre Hospitalier Universitaire de Liège - CHU > Chirurgie abdominale- endocrinienne et de transplantation
Meurisse, Michel ;  Université de Liège - ULiège > Département des sciences cliniques > Chirurgicale abdominale
Hamoir, Etienne ;  Centre Hospitalier Universitaire de Liège - CHU > Chirurgie abdominale- endocrinienne et de transplantation
Language :
English
Title :
Adrenal Ganglioneuroma. A Neoplasia to Exclude in Patients with Adrenal Incidentaloma
Publication date :
2007
Journal title :
Acta Chirurgica Belgica
ISSN :
0001-5458
Publisher :
Taylor & Francis, United Kingdom
Volume :
107
Issue :
6, Nov-Dec
Pages :
670-4
Peer reviewed :
Peer Reviewed verified by ORBi
Available on ORBi :
since 19 December 2020

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