Gonçalves, B.; Corassin, C.; Oliveira, C. Mycotoxicoses in Dairy Cattle: A Review. Asian J. Anim. Vet. Adv. 2015, 10, 752–760. [CrossRef]
Gbashi, S.; Madala, N.E.; de Saeger, S.; de Boevre, M.; Adekoya, I.; Adebo, O.A.; Njobeh, P.B. The Socio-Economic Impact of Mycotoxin Contamination in Africa. In Mycotoxins-Impact and Management Strategies; IntechOpen: London, UK, 2019; Available online: https://www.intechopen.com/online-first/the-socio-economic-impact-of-mycotoxin-contamination-in-africa (accessed on 23 September 2020). [CrossRef]
Njobeh, P.B.; Dutton, M.F.; Aberg, A.T.; Haggblom, P. Estimation of multi-mycotoxin contamination in South African compound feeds. Toxins 2012, 4, 836–848. [CrossRef]
Ali, M.A.I.; El-Zubeir, I.; Fadel Elseed, A.M.A. Aflatoxin M1 in raw and imported powdered milk sold in Khartoum state, Sudan. Food Addit. Contam. Part B 2014, 7, 208–212. [CrossRef]
Gizachew, D.; Szonyi, B.; Tegegne, A.; Hanson, J.; Grace, D. Aflatoxin contamination of milk and dairy feeds in the Greater Addis Ababa milk shed, Ethiopia. Food Control 2016, 59, 773–779. [CrossRef]
Kuilman, M.E.M. Bovine hepatic metabolism of aflatoxin B1. J. Agric. Food Chem. 1998, 46, 2707–2713. [CrossRef]
Lindahl, J.F.; Kagera, I.N.; Grace, D. Aflatoxin M1 levels in different marketed milk products in Nairobi, Kenya. Mycotoxin Res. 2018, 34, 289–295. [CrossRef] [PubMed]
Ribelin, W.E.; Fukushima, K.; Still, P.E. The toxicity of ochratoxin to ruminants. Can. J. Comp. Med. Rev. Can. Med. Comp. 1978, 42, 172–176.
World Health Organization; International Agency for Research on Cancer. Aflatoxins. IARC Monographs on the Evaluation of Carcinogenic Risks to Humans: Some Traditional Herbal Medicines, Some Mycotoxins, Naphthalene and Styrene; WHO: Geneva, Switzerland; IARC: Lyon, France, 2002.
Kang’ethe, E.K.; Lang’a, K.A. Aflatoxin B1 and M1 contamination of animal feeds and milk from urban centers in Kenya. Afr. Health Sci. 2009, 9, 218–226. [PubMed]
Makau, C.M.; Matofari, J.W.; Muliro, P.S.; Bebe, B.O. Aflatoxin B1 and Deoxynivalenol contamination of dairy feeds and presence of Aflatoxin M1 contamination in milk from smallholder dairy systems in Nakuru, Kenya. Int. J. Food Contam. 2016, 3, 6. [CrossRef]
Okoth, S.A.; Kola, M.A. Market samples as a source of chronic aflatoxin exposure in Kenya. Afr. J. Health Sci. 2012, 20, 56–61.
Rodrigues, I.; Handl, J.; Binder, E.M. Mycotoxin occurrence in commodities, feeds and feed ingredients sourced in the Middle East and Africa. Food Addit. Contam. Part B 2011, 4, 168–179. [CrossRef] [PubMed]
Sirma, A.; Daniel, S.; Lindahl, J.; Makita, K.; Kang’ethe, E.; Grace, D. Aflatoxin M1 survey in dairy households in Kenya. In Proceedings of the Food Africa Midterm Seminar, Helsinki, Finland, 16 June 2014.
Kemboi, D.C.; Antonissen, G.; Ochieng, P.E.; Croubels, S.; Okoth, S.; Kangethe, E.K.; Faas, J.; Lindahl, J.F.; Gathumbi, J.K. A Review of the Impact of Mycotoxins on Dairy Cattle Health: Challenges for Food Safety and Dairy Production in Sub-Saharan Africa. Toxins 2020, 12, 222. [CrossRef] [PubMed]
Escrivá, L.; Oueslati, S.; Font, G.; Manyes, L. Alternaria Mycotoxins in Food and Feed: An Overview. J. Food Qual. 2017, 2017, 1569748. [CrossRef]
Warth, B.; Parich, A.; Atehnkeng, J.; Bandyopadhyay, R.; Schuhmacher, R.; Sulyok, M.; Krska, R. Quantitation of Mycotoxins in Food and Feed from Burkina Faso and Mozambique Using a Modern LC-MS/MS Multitoxin Method. J. Agric. Food Chem. 2012, 60, 9352–9363. [CrossRef] [PubMed]
Streit, E.; Schwab, C.; Sulyok, M.; Naehrer, K.; Krska, R.; Schatzmayr, G. Multi-Mycotoxin Screening Reveals the Occurrence of 139 Different Secondary Metabolites in Feed and Feed Ingredients. Toxins 2013, 5, 504–523. [CrossRef]
Coufal-Majewski, S.; Stanford, K.; McAllister, T.; Blakley, B.; McKinnon, J.; Chaves, A.V.; Wang, Y. Impacts of Cereal Ergot in Food Animal Production. Front. Vet. Sci. 2016, 3, 15. [CrossRef]
Ezekiel, C.N.; Bandyopadhyay, R.; Sulyok, M.; Warth, B.; Krska, R. Fungal and bacterial metabolites in commercial poultry feed from Nigeria. Food Addit. Contam. Part Chem. Anal. Control Expo. Risk Assess. 2012, 29, 1288–1299. [CrossRef]
Hessenberger, S.; Botzi, K.; Degrassi, C.; Kovalsky, P.; Schwab, C.; Schatzmayr, D.; Schatzmayr, G.; Fink-Gremmels, J. Interactions between plant-derived oestrogenic substances and the mycoestrogen zearalenone in a bioassay with MCF-7 cells. Pol. J. Vet. Sci. 2017, 20, 513–520. [CrossRef]
Miazzo, R.; Peralta, M.F.; Magnoli, C.; Salvano, M.; Ferrero, S.; Chiacchiera, S.; Carvalho, E.C.Q.; Rosa, C.A.R.; Dalcero, A.M. Efficacy of sodium bentonite as a detoxifier of broiler feed contaminated with aflatoxin and fumonisin. Poult. Sci. 2005, 84, 1–8. [CrossRef]
Dänicke, S.; Winkler, J. Invited review: Diagnosis of zearalenone (ZEN) exposure of farm animals andtransfer of its residues into edible tissues (carry over). Food Chem. Toxicol. Int. J. Publ. Br. Ind. Biol. Res. Assoc. 2015, 84, 225–249. [CrossRef] [PubMed]
Changwa, R.; Abia, W.; Msagati, T.; Nyoni, H.; Ndleve, K.; Njobeh, P. Multi-Mycotoxin Occurrence in Dairy Cattle Feeds from the Gauteng Province of South Africa: A Pilot Study Using UHPLC-QTOF-MS/MS. Toxins 2018, 10, 294. [CrossRef] [PubMed]
Nyangi, C. Aflatoxins and fumonisin contamination of marketed maize, maize bran and maize used as animal feed in Northern Tanzania. Afr. J. Food Agric. Nutr. Dev. 2016, 16, 11054–11065. [CrossRef]
Huff, W.E.; Kubena, L.F.; Harvey, R.B.; Hagler, W.M.J.; Swanson, S.P.; Phillips, T.D.; Creger, C.R. Individual and combined effects of aflatoxin and deoxynivalenol (DON, vomitoxin) in broiler chickens. Poult. Sci. 1986, 65, 1291–1298. [CrossRef]
Murugesan, G.R.; Ledoux, D.R.; Naehrer, K.; Berthiller, F.; Applegate, T.J.; Grenier, B.; Phillips, T.D.; Schatzmayr, G. Prevalence and effects of mycotoxins on poultry health and performance, and recent development in mycotoxin counteracting strategies. Poult. Sci. 2015, 94, 1298–1315. [CrossRef]
Broekaert, N.; Devreese, M.; van Bergen, T.; Schauvliege, S.; De Boevre, M.; De Saeger, S.; Vanhaecke, L.; Berthiller, F.; Michlmayr, H.; Malachová, A.; et al. In vivo contribution of deoxynivalenol-3-β-d-glucoside to deoxynivalenol exposure in broiler chickens and pigs: Oral bioavailability, hydrolysis and toxicokinetics. Arch. Toxicol. 2017, 91, 699–712. [CrossRef]
Senerwa, D.M.; Mtimet, N.; Sirma, A.J.; Nzuma, J.; Kang’ethe, E.K.; Lindahl, J.F.; Grace, D. Direct market costs of aflatoxins in Kenyan dairy value chain. In Proceedings of the ANH Academy Week, Addis Ababa, Ethiopia, 20–24 June 2016.
Mohammed, S.; Munissi, J.J.E.; Nyandoro, S.S. Aflatoxin M1 in raw milk and aflatoxin B1 in feed from household cows in Singida, Tanzania. Food Addit. Contam. Part B Surveill. 2016, 9, 85–90. [CrossRef]
Kirino, Y.; Makita, K.; Grace, D.; Lindahl, J. Survey of informal milk retailers in Nairobi, Kenya and prevalence of aflatoxin M1 in marketed milk. Afr. J. Food Agric. Nutr. Dev. 2016, 16, 11022–11038. [CrossRef]
Mulunda, F. Determination and Quantification of Aflatoxin M1 in Fresh Milk Samples Obtained in Goats and Cattle in Selected Rural Areas of the Limpopo Province, South Africa. J. Hum. Ecol. 2016, 56, 183–187. [CrossRef]
Kagera, I.; Kahenya, P.; Mutua, F.; Anyango, G.; Kyallo, F.; Grace, D.; Lindahl, J. Status of aflatoxin contamination in cow milk produced in smallholder dairy farms in urban and peri-urban areas of Nairobi County: A case study of Kasarani sub county, Kenya. Infect. Ecol. Epidemiol. 2018, 9, 1547095. [CrossRef] [PubMed]
Oluwafemi, F.; Badmos, A.; Kareem, S.; Ademuyiwa, O.; Kolapo, A. Survey of aflatoxin M1 in cows’ milk from free-grazing cows in Abeokuta, Nigeria. Mycotoxin Res. 2014, 30. [CrossRef] [PubMed]
Kuboka, M.M.; Imungi, J.K.; Njue, L.; Mutua, F.; Grace, D.; Lindahl, J.F. Occurrence of aflatoxin M1 in raw milk traded in peri-urban Nairobi, and the effect of boiling and fermentation. Infect. Ecol. Epidemiol. 2019, 9, 1625703. [CrossRef] [PubMed]
Sumantri, I.; Murti, T.W.; van der Poel, A.F.B.; Boehm, J.; Agus, A. Carry-over of aflatoxin B1-feed into aflatoxin M1-milk in dairy cows treated with natural sources of aflatoxin and bentonite. J. Indones. Trop. Anim. Agric. 2012, 37, 271–277. [CrossRef]
Coppock, R.W.; Christian, R.R.G.; Jacobsen, B.J. Aflatoxins. In Veterinary Toxicology: Basic and Clinical Principles; Academic Press: Cambridge, MA, USA, 2012.
Herzallah, S. Aflatoxin B1 residues in eggs and flesh of laying hens fed aflatoxin B1 contaminated diet. Am. J. Agric. Biol. Sci. 2013, 8, 156–161. [CrossRef]
Iqbal, S.Z.; Nisar, S.; Asi, M.R.; Jinap, S. Natural incidence of aflatoxins, ochratoxin A and zearalenone in chicken meat and eggs. Food Control 2014, 43, 98–103. [CrossRef]
Sirma, A.J.; Lindahl, J.F.; Makita, K.; Senerwa, D.; Mtimet, N.; Kang’ethe, E.K.; Grace, D. The impacts of aflatoxin standards on health and nutrition in sub-Saharan Africa: The case of Kenya. Glob. Food Secur. 2018, 18, 57–61. [CrossRef]
Bailey, C.A.; Fazzino, J.J.J.; Ziehr, M.S.; Sattar, M.; Haq, A.U.; Odvody, G. Evaluation of sorghum ergot toxicity in broilers. Poult. Sci. 1999, 78, 1391–1397. [CrossRef]
Ingenbleek, L.; Sulyok, M.; Adegboye, A.; Hossou, S.E.; Koné, A.Z.; Oyedele, A.D.; Kisito, C.S.K.J.; Koreissi Dembélé, Y.; Eyangoh, S.; Verger, P.; et al. Regional Sub-Saharan Africa Total Diet Study in Benin, Cameroon, Mali and Nigeria Reveals the Presence of 164 Mycotoxins and Other Secondary Metabolites in Foods. Toxins 2019, 11, 54. [CrossRef]
European Commission (EC). Setting Maximum Levels for Certain Contaminants in Foodstuffs; EC: Brussels, Belgium, 2006.
Dvorska, J.E.; Surai, P.F.; Speake, B.K.; Sparks, N.H.C. Effect of the mycotoxin aurofusarin on the antioxidant composition and fatty acid profile of quail eggs. Br. Poult. Sci. 2001, 42, 643–649. [CrossRef]
Broomhead, J.N.; Ledoux, D.R.; Bermudez, A.J.; Rottinghaus, G.E. Chronic Effects of Moniliformin in Broilers and Turkeys Fed Dietary Treatments to Market Age. Avian Dis. 2002, 46, 901–908. [CrossRef]
Harvey, R.; Edrington, T.; Kubena, L.; Rottinghaus, G.; Turk, J.; Genovese, K.; Nisbet, D. Toxicity of moniliformin from Fusarium fujikuroi culture material to growing barrows. J. Food Prot. 2001, 64, 1780–1784. [CrossRef] [PubMed]
Lamprecht, S.C.; Marasas, W.F.O.; Thiel, P.G.; Schneider, D.J.; Knox-Davies, P.S. Incidence and toxigenicity of seedborne Fusarium species from annual Medicago species in South Africa. Phytopathology 1986, 76, 1040–1042. [CrossRef]
Kubena, L.; Harvey, R.; Buckley, S.; Edrington, T.; Rottinghaus, G. Individual and combined effects of moniliformin present in Fusarium fujikuroi culture material and aflatoxin in broiler chicks. Poult. Sci. 1997, 76, 265–270. [CrossRef] [PubMed]
Harvey, R.B.; Kubena, L.F.; Rottinghaus, G.E.; Turk, J.R.; Casper, H.H.; Buckley, S.A. Moniliformin from Fusarium fujikuroi culture material and deoxynivalenol from naturally contaminated wheat incorporated into diets of broiler chicks. Avian Dis. 1997, 41, 957–963. [CrossRef]
Harvey, B.; Edrington, T.S.; Kubena, L.F.; Rottinghaus, G.E.; Turk, J.R.; Genovese, K.J.; Ziprin, R.L.; Nisbet, D.J. Toxicity of fumonisin from Fusarium verticillioides culture material and moniliformin from Fusarium fujikuroi culture material when fed singly and in combination to growing barrows. J. Food Prot. 2002, 65, 373–377. [CrossRef]
Jestoi, M. Emerging fusarium-mycotoxins fusaproliferin, beauvericin, enniatins, and moniliformin: A review. Crit. Rev. Food Sci. Nutr. 2008, 48, 21–49. [CrossRef]
Fraeyman, S.; Croubels, S.; Devreese, M.; Ducatelle, R.; Rychlik, M.; Antonissen, G. Chronic Dietary Intake of Enniatin B in Broiler Chickens Has Low Impact on Intestinal Morphometry and Hepatic Histology, and Shows Limited Transfer to Liver Tissue. Toxins 2018, 10, 45. [CrossRef]
Wells, J.M.; Cole, R.J.; Kirksey, J.W. Emodin, a toxic metabolite of Aspergillus wentii isolated from weevil-damaged chestnuts. Appl. Microbiol. 1975, 30, 26–28. [CrossRef]
Grenier, B.; Oswald, I. Mycotoxin co-contamination of food and feed: Meta-Analysis of publications describing toxicological interactions. World Mycotoxin J. 2011, 4, 285–313. [CrossRef]
Klaric, M.S.; Rasic, D.; Peraica, M. Deleterious effects of mycotoxin combinations involving ochratoxin A. Toxins 2013, 5, 1965–1987. [CrossRef] [PubMed]
Stoev, S.D.; Paskalev, M.; MacDonald, S.; Mantle, P.G. Experimental one year ochratoxin a toxicosis in pigs. Exp. Toxicol. Pathol. Off. J. Ges. Toxikol. Pathol. 2002, 53, 481–487. [CrossRef] [PubMed]
Gruber-Dorninger, C.; Jenkins, T.; Schatzmayr, G. Global Mycotoxin Occurrence in Feed: A Ten-Year Survey. Toxins 2019, 11, 375. [CrossRef]
Kang’ethe, E.K.; Korhonen, H.; Marimba, K.A.; Nduhiu, G.; Mungatu, J.K.; Okoth, S.A.; Joutsjoki, V.; Wamae, L.W.; Shalo, P. Management and mitigation of health risks associated with the occurrence of mycotoxins along the maize value chain in two counties in Kenya. Food Qual. Saf. 2017, 1, 268–274. [CrossRef]
Sulyok, M.; Stadler, D.; Steiner, D.; Krska, R. Validation of an LC-MS/MS-Based Dilute-and-Shoot Approach for the Quantification of > 500 Mycotoxins and Other Secondary Metabolites in Food Crops: Challenges and Solutions. Anal. and Bioanal. Chem. 2020, 412, 2607–2620. [CrossRef]