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The impact of endocrine disruptors on female pubertal timing
Bourguignon, Jean-Pierre; Parent, Anne-Simone
2012In Diamanti-Kandarakis, E; Gore, A. C. (Eds.) Endocrine Disruptors and Puberty
 

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Keywords :
Adiponectin; Nutrition; Puberty; Reproduction; Energy balance; GnRH; Homeostasis; Intrauterine growth retardation
Abstract :
[en] Secular changes in pubertal timing and particular forms of sexual precocity after migration to new geographical areas whose levels of environment differ from those in the natal country suggest that endocrine-disrupting compounds (EDCs) may be involved. Studies in humans based on measurement of some EDC in relation to pubertal timing are inconclusive for several possible reasons including predominant genetic determinism and effects of complex EDC mixtures. Based on animal models, some possible neuroendocrine mechanisms are discussed as well as the interrelation between the homeostasis of reproduction and energy balance. © 2012, Springer Science+Business Media, LLC.
Disciplines :
Endocrinology, metabolism & nutrition
Author, co-author :
Bourguignon, Jean-Pierre ;  Université de Liège - ULiège > Département des sciences cliniques > Département des sciences cliniques
Parent, Anne-Simone ;  Université de Liège - ULiège > Département des sciences cliniques > Pédiatrie
Language :
English
Title :
The impact of endocrine disruptors on female pubertal timing
Publication date :
2012
Main work title :
Endocrine Disruptors and Puberty
Author, co-author :
Diamanti-Kandarakis, E
Gore, A. C.
Publisher :
Humana Press Inc., Germany
ISBN/EAN :
978-1-60761-560-6
Collection name :
Contemporary Endocrinology
Pages :
325-337
Funders :
FEDER - Fonds Européen de Développement Régional [BE]
F.R.S.-FNRS - Fonds de la Recherche Scientifique [BE]
Fonds Léon Fredericq [BE]
BSGPE - Belgian Study Group for Pediatric Endocrinology [BE]
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