Biochemical characterization of the TEM-107 extended-spectrum β-lactamase in a Klebsiella pneumoniae isolate from South Korea

Lee, K.; Yum, J. H.; Yong, D.; Jeong, S. H.; Rossolini, G. M.; Docquier, Jean-Denis; Chong, Y.

doi:10.1128/AAC.05341-11

Article (Scientific journals)

Biochemical characterization of the TEM-107 extended-spectrum β-lactamase in a Klebsiella pneumoniae isolate from South Korea

Lee, K.; Yum, J. H.; Yong, D. et al.

2011 • In Antimicrobial Agents and Chemotherapy, 55 (12), p. 5930-5932

Peer Reviewed verified by ORBi

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https://hdl.handle.net/2268/252846

DOI
10.1128/AAC.05341-11

PubMed
21911565

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Keywords :

Klebsiella pneumoniae; South Korea; Adolescent; Amino Acid Substitution; Anti-Bacterial Agents; Cefotaxime; Ceftazidime; Clavulanic Acid; Conjugation, Genetic; Escherichia coli; Female; Humans; Kinetics; Klebsiella Infections; Microbial Sensitivity Tests; Republic of Korea

Abstract :

[en] The TEM-107 extended-spectrum β-lactamase detected in a Klebsiella pneumoniae clinical isolate had a Gly238Ser substitution compared to the TEM-43 β-lactamase. The MIC of ceftazidime was higher (64 μg/ml) than that of cefotaxime (2 μg/ml) for the isolate. Clavulanic acid reduced the MIC of ceftazidime 64-fold. Copyright © 2011, American Society for Microbiology. All Rights Reserved.

Disciplines :

Biochemistry, biophysics & molecular biology
Microbiology

Author, co-author :

Lee, K.; Department of Laboratory Medicine, Research Institute of Bacterial Resistance, Yonsei University College of Medicine, Seoul, South Korea

Yum, J. H.; Department of Clinical Laboratory Science, Dong-eui University, Busan, South Korea

Yong, D.; Department of Laboratory Medicine, Research Institute of Bacterial Resistance, Yonsei University College of Medicine, Seoul, South Korea

Jeong, S. H.; Department of Laboratory Medicine, Research Institute of Bacterial Resistance, Yonsei University College of Medicine, Seoul, South Korea

Rossolini, G. M.; Dipartimento di Biologia Molecolare, Sezione di Microbiologia, Università di Siena, I-53100 Siena, Italy

Docquier, Jean-Denis ; Université de Liège - ULiège > Département des sciences de la vie > Centre d'ingénierie des protéines

Chong, Y.; Department of Laboratory Medicine, Research Institute of Bacterial Resistance, Yonsei University College of Medicine, Seoul, South Korea

Language :

English

Title :

Biochemical characterization of the TEM-107 extended-spectrum β-lactamase in a Klebsiella pneumoniae isolate from South Korea

Publication date :

2011

Journal title :

Antimicrobial Agents and Chemotherapy

ISSN :

0066-4804

eISSN :

1098-6596

Publisher :

American Society for Microbiology, Washington, United States - District of Columbia

Volume :

Issue :

Pages :

5930-5932

Peer reviewed :

Peer Reviewed verified by ORBi

Available on ORBi :

since 20 November 2020

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Bibliography

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