Profil

Docquier Jean-Denis

Département des sciences de la vie

See author's contact details
Main Referenced Co-authors
Rossolini, G. M. (56)
De Luca, F. (31)
Frère, Jean-Marie  (19)
Mangani, S. (18)
Benvenuti, M. (16)
Main Referenced Keywords
Humans (36); Escherichia coli (33); Microbial Sensitivity Tests (31); Anti-Bacterial Agents (30); Pseudomonas aeruginosa (30);
Main Referenced Unit & Research Centers
CIP - Centre d'Ingénierie des Protéines - ULiège [BE] (1)
Main Referenced Disciplines
Microbiology (102)
Biochemistry, biophysics & molecular biology (61)
Life sciences: Multidisciplinary, general & others (16)
Immunology & infectious disease (8)
Pharmacy, pharmacology & toxicology (6)

Publications (total 118)

The most downloaded
163 downloads
MEEX, C., MELIN, P., Docquier, J.-D., Kabasele, T., HUYNEN, P., Tulkens, P., Giet, D., & De Mol, P. (2008). Presenec of extended-spectrum beta-lactamase-producing Enterobacteriaceae in the fecal flora of patients from general practice. In ECCMID (Ed.), Program and Abstracts book of the 18th ECCMID. https://hdl.handle.net/2268/38372

The most cited

300 citations (Scopus®)

Lee, K., Yum, J. H., Yong, D., Lee, H. M., Kim, H. D., Docquier, J.-D., Rossolini, G. M., & Chong, Y. (2005). Novel acquired metallo-β-lactamase gene, blaSIM-1, in a class 1 integron from Acinetobacter baumannii clinical isolates from Korea. Antimicrobial Agents and Chemotherapy, 49 (11), 4485-4491. doi:10.1128/AAC.49.11.4485-4491.2005 https://hdl.handle.net/2268/252993

Martinet, L., Naômé, A., Rezende, L. C. D., Tellatin, D., Pignon, B., Docquier, J.-D., Sannio, F., Baiwir, D., Mazzucchelli, G., Frederich, M., & Rigali, S. (06 January 2023). Lunaemycins, New Cyclic Hexapeptide Antibiotics from the Cave Moonmilk-Dweller Streptomyces lunaelactis MM109T. International Journal of Molecular Sciences, 24 (2), 1114. doi:10.3390/ijms24021114
Peer Reviewed verified by ORBi

ROSALES-HURTADO, M., Sannio, F., Lari, L., Verdirosa, F., Feller, G., Carretero, E., Vo Hoang, Y., Licznar-Fajardo, P., Docquier, J.-D., & Gavara, L. (2023). Zidovudine-β-lactam pronucleoside strategy for selective delivery into Gram-negative bacteria triggered by β-lactamases. ACS Infectious Diseases, 9, 1546-1557. doi:10.1021/acsinfecdis.3c00110
Peer Reviewed verified by ORBi

Sannio, F., Brizzi, A., Del Prete, R., Avigliano, M., Simone, T., Pagli, C., Ferraro, T., De Luca, F., Paolino, M., Corelli, F., Mugnaini, C., & Docquier, J.-D. (16 December 2022). Optimization of Pyrazole Compounds as Antibiotic Adjuvants Active against Colistin- and Carbapenem-Resistant Acinetobacter baumannii. Antibiotics, 11 (12), 1832. doi:10.3390/antibiotics11121832
Peer reviewed

Legru, A.* , Verdirosa, F.* , Vo-Hoang, Y., Tassone, G., Vascon, F., Thomas, C. A., Sannio, F., Corsica, G., Benvenuti, M., Feller, G., Coulon, R., Marcoccia, F., Devente, S. R., Bouajila, E., Piveteau, C., Leroux, F., Deprez-Poulain, R., Deprez, B., Licznar-Fajardo, P., ... Gavara, L.*. (30 November 2022). Optimization of 1,2,4-Triazole-3-thiones toward Broad-Spectrum Metallo-β-lactamase Inhibitors Showing Potent Synergistic Activity on VIM- and NDM-1-Producing Clinical Isolates. Journal of Medicinal Chemistry, 65, 16392-16419. doi:10.1021/acs.jmedchem.2c01257
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

Caburet, J., Boucherle, B., Bourdillon, S., Simoncelli, G., Verdirosa, F., Docquier, J.-D., Moreau, Y., Krimm, I., Crouzy, S., & Peuchmaur, M. (05 October 2022). A fragment-based drug discovery strategy applied to the identification of NDM-1 β-lactamase inhibitors. European Journal of Medicinal Chemistry, 240, 114599. doi:10.1016/j.ejmech.2022.114599
Peer Reviewed verified by ORBi

Legru, A., Gavara L., Verdirosa F., Vo-Hoang Y., Tassone G., Corsica G., Vascone F., Thomas C., Feller, G., Crowder M., Cendron L., Pozzi C., Mangani S., Docquier, J.-D., & Hernandez J.-F. (04 September 2022). 1,2,4-TRIAZOLE-3-THIONE COMPOUNDS POTENTLY INHIBIT VIM AND NDM-1 METALLO-b-LACTAMASES AND RE-SENSITIZE MULTI-RESISTANT CLINICAL ISOLATES TO MEROPENEM [Poster presentation]. International Symposium on Medicinal Chemistry, Nice, France.
Editorial reviewed

Ardino, C., Sannio, F., Pasero, C., Botta, L., Dreassi, E., Docquier, J.-D.* , & D'Agostino, I.*. (2022). The impact of counterions in biological activity: case study of antibacterial alkylguanidino ureas. Molecular Diversity, 1 - 11. doi:10.1007/s11030-022-10505-6
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

Gavara, L., Verdirosa, F., Sevaille, L., Legru, A., Corsica, G., Nauton, L., Mercuri, P., Sannio, F., De Luca, F., Hadjadj, M., Cerboni, G., Vo Hoang, Y., Licznar-Fajardo, P., Galleni, M., Docquier, J.-D., & Hernandez, J.-F. (11 August 2022). 1,2,4-Triazole-3-thione analogues with an arylakyl group at position 4 as metallo-β-lactamase inhibitors. Bioorganic and Medicinal Chemistry, 72, 116964. doi:10.1016/j.bmc.2022.116964
Peer Reviewed verified by ORBi

Martina, M. G.* , Sannio, F.* , Crespan, E., Pavone, M., Simoncini, A., Barbieri, F., Perini, C., Pesce, E., Maga, G., Pedemonte, N., Docquier, J.-D., & Radi, M. (2022). Towards Innovative Antibacterial-Correctors for Cystic Fibrosis Targeting the Lung Microbiome with a Multifunctional Effect. ChemMedChem. doi:10.1002/cmdc.202200277
Peer Reviewed verified by ORBi
* These authors have contributed equally to this work.

D'Agostino, I., Ardino, C., Poli, G., Sannio, F., Lucidi, M., Poggialini, F., Visaggio, D., Rango, E., Filippi, S., Petricci, E., Visca, P., Botta, L., Docquier, J.-D., & Dreassi, E. (05 March 2022). Antibacterial alkylguanidino ureas: Molecular simplification approach, searching for membrane-based MoA. European Journal of Medicinal Chemistry, 231, 114158. doi:10.1016/j.ejmech.2022.114158
Peer Reviewed verified by ORBi

Verdirosa, F.* , Gavara, L.* , Sevaille, L., Tassone, G., Corsica, G., Legru, A., Feller, G., Chelini, G., Mercuri, P., Tanfoni, S., Sannio, F., Benvenuti, M., Cerboni, G., De Luca, F., Bouajila, E., Hoang, Y. V., Licznar-Fajardo, P., Galleni, M., Pozzi, C., ... Hernandez, J.-F.*. (20 January 2022). 1,2,4-Triazole-3-Thione Analogues with a 2-Ethylbenzoic Acid at Position 4 as VIM-type Metallo-β-Lactamase Inhibitors. ChemMedChem, 17 (7), 202100699. doi:10.1002/cmdc.202100699
Peer reviewed
* These authors have contributed equally to this work.

Papp-Wallace, K. M., Docquier, J.-D., Kerff, F., & Power, P. (2022). Editorial: Structural and Biochemical Aspects of the Interaction of β-Lactamases With State-of-the-Art Inhibitors. Frontiers in Microbiology, 13, 849324. doi:10.3389/fmicb.2022.849324
Peer Reviewed verified by ORBi

Legru, A., Verdirosa, F., Vo-Hoang, Y., Tassone, G., Vascon, F., Thomas, C., Sannio, F., Corsica, G., Benvenuti, M., Feller, G., Coulon, R., Marcoccia, F., Devente, S., Bouajila, E., Piveteau, C., Leroux, F., Deprez-Poulain, R., Deprez, B., Licznar-Fajardo, P., ... Gavara, L. (2022). Optimization of 1,2,4-triazole-3-thiones towards broad-spectrum metallo-β-lactamase inhibitors showing potent synergistic activity on VIM- and NDM-1-producing clinical isolates. Journal of Medicinal Chemistry.
Peer Reviewed verified by ORBi

Terrosi, C., Anichini, G., Docquier, J.-D., Gori Savellini, G., Gandolfo, C., Pavone, F. S., & Cusi, M. G. (08 December 2021). Efficient Inactivation of SARS-CoV-2 and Other RNA or DNA Viruses with Blue LED Light. Pathogens (Basel, Switzerland), 10 (12), 1590. doi:10.3390/pathogens10121590
Peer reviewed

Kwapien, K., Gavara, L., Docquier, J.-D., Berthomieu, D., Hernandez, J.-F., & Gresh, N. (2021). Intermolecular interactions of the extended recognition site of VIM-2 metallo-β-lactamase with 1,2,4-triazole-3-thione inhibitors. Validations of a polarizable molecular mechanics potential by ab initio QC. Journal of Computational Chemistry, 42 (2), 86-106. doi:10.1002/jcc.26437
Peer Reviewed verified by ORBi

Gavara, L., Legru, A., Verdirosa, F., Sevaille, L., Nauton, L., Corsica, G., Mercuri, P., Sannio, F., Feller, G., Coulon, R., De Luca, F., Cerboni, G., Tanfoni, S., Chelini, G., Galleni, M., Docquier, J.-D., & Hernandez, J.-F. (2021). 4-Alkyl-1,2,4-triazole-3-thione analogues as metallo-β-lactamase inhibitors. Bioorganic Chemistry, 113. doi:10.1016/j.bioorg.2021.105024
Peer Reviewed verified by ORBi

Martin, M. J., Corey, B. W., Sannio, F., Hall, L. R., MacDonald, U., Jones, B. T., Mills, E. G., Harless, C., Stam, J., Maybank, R., Kwak, Y., Schaufler, K., Becker, K., Hübner, N.-O., Cresti, S., Tordini, G., Valassina, M., Cusi, M. G., Bennett, J. W., ... Docquier, J.-D. (2021). Anatomy of an extensively drug-resistant Klebsiella pneumoniae outbreak in Tuscany, Italy. Proceedings of the National Academy of Sciences, 118 (48 e2110227118). doi:10.1073/pnas.2110227118
Peer reviewed

Legru, A., Verdirosa, F., Hernandez, J.-F., Tassone, G., Sannio, F., Benvenuti, M., Conde, P.-A., Bossis, G., Thomas, C. A., Crowder, M. W., Dillenberger, M., Becker, K., Pozzi, C., Mangani, S., Docquier, J.-D., & Gavara, L. (2021). 1,2,4-Triazole-3-thione compounds with a 4-ethyl alkyl/aryl sulfide substituent are broad-spectrum metallo-β-lactamase inhibitors with re-sensitization activity. European Journal of Medicinal Chemistry, 226, 113873. doi:10.1016/j.ejmech.2021.113873
Peer Reviewed verified by ORBi

Davies, D. T., Leiris, S., Zalacain, M., Sprynski, N., Castandet, J., Bousquet, J., Lozano, C., Llanos, A., Alibaud, L., Vasa, S., Pattipati, R., Valige, R., Kummari, B., Pothukanuri, S., De Piano, C., Morrissey, I., Holden, K., Warn, P., Marcoccia, F., ... Everett, M. (December 2020). Discovery of ANT3310, a Novel Broad-Spectrum Serine β-Lactamase Inhibitor of the Diazabicyclooctane Class, Which Strongly Potentiates Meropenem Activity against Carbapenem-Resistant Enterobacterales and Acinetobacter baumannii. Journal of Medicinal Chemistry, 63 (24), 15802–15820. doi:10.1021/acs.jmedchem.0c01535
Peer Reviewed verified by ORBi

Marcoccia, F., Sannio, F., De Luca, F., Benvenuti, M., Pozzi, C., Mangani, S., Sprynski, N., Leiris, S., Everett, M., & Docquier, J.-D. (April 2020). Interaction of the new diazabicyclooctanone (DBO) β-lactamase inhibitor ANT3310 with clinically relevant β-lactamases: a biochemical and structural study [Poster presentation]. 30th European Congress of Clinical Microbiology and Infectious Diseases (ECCMID), Paris, France.

Bassini, E., Gazzotti, S., Sannio, F., Presti, L. L., Sgrignani, J., Docquier, J.-D., Grazioso, G., & Silvani, A. (2020). Isonitrile-based multicomponent synthesis of β-amino boronic acids as β-lactamase inhibitors. Antibiotics, 9 (5), 1-21. doi:10.3390/antibiotics9050249
Peer Reviewed verified by ORBi

Gavara, L., Verdirosa, F., Legru, A., Mercuri, P., Nauton, L., Sevaille, L., Feller, G., Berthomieu, D., Sannio, F., Marcoccia, F., Tanfoni, S., De Luca, F., Gresh, N., Galleni, M., Docquier, J.-D., & Hernandez, J.-F. (2020). 4-(N-Alkyl- and -Acyl-amino)-1,2,4-triazole-3-thione Analogs as Metallo-Beta-Lactamase Inhibitors: Impact of 4-Linker on Potency and Spectrum of Inhibition. Biomolecules, 10 (8), 1094. doi:10.3390/biom10081094
Peer Reviewed verified by ORBi

Gavara, L., Sevaille, L., De Luca, F., Mercuri, P., Bebrone, C., Feller, G., Legru, A., Cerboni, G., Tanfoni, S., Baud, D., Cutolo, G., Bestgen, B., Chelini, G., Verdirosa, F., Sannio, F., Pozzi, C., Benvenuti, M., Kwapien, K., Fischer, M., ... Hernandez, J.-F. (2020). 4-Amino-1,2,4-triazole-3-thione-derived Schiff bases as metallo-beta-lactamase inhibitors. European Journal of Medicinal Chemistry, 208, 112720. doi:10.1016/j.ejmech.2020.112720
Peer Reviewed verified by ORBi

Mugnaini, C., Sannio, F., Brizzi, A., Del Prete, R., Simone, T., Ferraro, T., De Luca, F., Corelli, F., & Docquier, J.-D. (2020). Screen of Unfocused Libraries Identified Compounds with Direct or Synergistic Antibacterial Activity. ACS Medicinal Chemistry Letters, 11 (5), 899-905. doi:10.1021/acsmedchemlett.9b00674
Peer Reviewed verified by ORBi

Hamrick, J. C., Docquier, J.-D., Uehara, T., Myers, C. L., Six, D. A., Chatwin, C. L., John, K. J., Vernacchio, S. F., Cusick, S. M., Trout, R. E. L., Pozzi, C., De Luca, F., Benvenuti, M., Mangani, S., Liu, B., Jackson, R. W., Moeck, G., Xerri, L., Burns, C. J., ... Daigle, D. M. (2020). VNRX-5133 (Taniborbactam), a broad-spectrum inhibitor of serine- And metallo-β-lactamases, restores activity of cefepime in enterobacterales and Pseudomonas aeruginosa. Antimicrobial Agents and Chemotherapy, 64 (3). doi:10.1128/AAC.01963-19
Peer Reviewed verified by ORBi

Liu, B., Trout, R. E. L., Chu, G.-H., Mcgarry, D., Jackson, R. W., Hamrick, J. C., Daigle, D. M., Cusick, S. M., Pozzi, C., De Luca, F., Benvenuti, M., Mangani, S., Docquier, J.-D., Weiss, W. J., Pevear, D. C., Xerri, L., & Burns, C. J. (2020). Discovery of Taniborbactam (VNRX-5133): A Broad-Spectrum Serine- And Metallo-β-lactamase Inhibitor for Carbapenem-Resistant Bacterial Infections. Journal of Medicinal Chemistry, 63 (6), 2789-2801. doi:10.1021/acs.jmedchem.9b01518
Peer Reviewed verified by ORBi

Mack, A. R., Barnes, M. D., Taracila, M. A., Hujer, A. M., Hujer, K. M., Cabot, G., Feldgarden, M., Haft, D. H., Klimke, W., Van Den Akker, F., Vila, A. J., Smania, A., Haider, S., Papp-Wallace, K. M., Bradford, P. A., Rossolini, G. M., Docquier, J.-D., Frère, J.-M., Galleni, M., ... Bonomo, R. A. (2020). A standard numbering scheme for class C β-lactamases. Antimicrobial Agents and Chemotherapy, 64 (3). doi:10.1128/AAC.01841-19
Peer Reviewed verified by ORBi

Davies, D. T., Leiris, S., Sprynski, N., Castandet, J., Lozano, C., Bousquet, J., Zalacain, M., Vasa, S., Dasari, P. K., Pattipati, R., Vempala, N., Gujjewar, S., Godi, S., Jallala, R., Sathyap, R. R., Darshanoju, N. A., Ravu, V. R., Juventhala, R. R., Pottabathini, N., ... Everett, M. (2020). ANT2681: SAR Studies Leading to the Identification of a Metallo-β-lactamase Inhibitor with Potential for Clinical Use in Combination with Meropenem for the Treatment of Infections Caused by NDM-Producing Enterobacteriaceae. ACS Infectious Diseases, 6 (9), 2419-2430. doi:10.1021/acsinfecdis.0c00207
Peer Reviewed verified by ORBi

Piccirilli, A., Brisdelli, F., Docquier, J.-D., Aschi, M., Cherubini, S., De Luca, F., Matagne, A., Amicosante, G., & Perilli, M. (2020). Amino acid replacement at position 228 induces fluctuation in the Ω-loop of KPC-3 and reduces the affinity against oxyimino cephalosporins: Kinetic and molecular dynamics studies. Catalysts, 10 (12), 1-14. doi:10.3390/catal10121474
Peer Reviewed verified by ORBi

Spyrakis, F., Santucci, M., Maso, L., Cross, S., Gianquinto, E., Sannio, F., Verdirosa, F., De Luca, F., Docquier, J.-D., Cendron, L., Tondi, D., Venturelli, A., Cruciani, G., & Costi, M. P. (2020). Virtual screening identifies broad-spectrum β-lactamase inhibitors with activity on clinically relevant serine- and metallo-carbapenemases. Scientific Reports, 10 (1). doi:10.1038/s41598-020-69431-y
Peer Reviewed verified by ORBi

Leiris, S., Coelho, A., Castandet, J., Bayet, M., Lozano, C., Bougnon, J., Bousquet, J., Everett, M., Lemonnier, M., Sprynski, N., Zalacain, M., Pallin, T. D., Cramp, M. C., Jennings, N., Raphy, G., Jones, M. W., Pattipati, R., Shankar, B., Sivasubrahmanyam, R., ... Davies, D. T. (2019). SAR Studies Leading to the Identification of a Novel Series of Metallo-β-lactamase Inhibitors for the Treatment of Carbapenem-Resistant Enterobacteriaceae Infections That Display Efficacy in an Animal Infection Model. ACS Infectious Diseases, 5 (1), 131-140. doi:10.1021/acsinfecdis.8b00246
Peer Reviewed verified by ORBi

Cecchini, T., Yoon, E.-J., Charretier, Y., Bardet, C., Beaulieu, C., Lacoux, X., Docquier, J.-D., Lemoine, J., Courvalin, P., Grillot-Courvalin, C., & Charrier, J.-P. (2018). Deciphering multifactorial resistance phenotypes in acinetobacter baumannii by genomics and targeted label-free proteomics. Molecular and Cellular Proteomics, 17 (3), 442-456. doi:10.1074/mcp.RA117.000107
Peer Reviewed verified by ORBi

Everett, M., Sprynski, N., Coelho, A., Castandet, J., Bayet, M., Bougnon, J., Lozano, C., Davies, D. T., Leiris, S., Zalacain, M., Morrissey, I., Magnet, S., Holden, K., Warn, P., De Luca, F., Docquier, J.-D., & Lemonniera, M. (2018). Discovery of a novel metallo-beta-lactamase inhibitor that potentiates meropenem activity against carbapenem-resistant enterobacteriaceae. Antimicrobial Agents and Chemotherapy, 62 (5). doi:10.1128/AAC.00074-18
Peer Reviewed verified by ORBi

Di Pisa, F., Pozzi, C., Benvenuti, M., Docquier, J.-D., De Luca, F., & Mangani, S. (2018). Boric acid and acetate anion binding to subclass B3 metallo-β-lactamase BJP-1 provides clues for mechanism of action and inhibitor design. Inorganica Chimica Acta, 470, 331-341. doi:10.1016/j.ica.2017.07.030
Peer Reviewed verified by ORBi

Pozzi, C., Di Pisa, F., De Luca, F., Benvenuti, M., Docquier, J.-D., & Mangani, S. (2018). Atomic-Resolution Structure of a Class C β-Lactamase and Its Complex with Avibactam. ChemMedChem, 13 (14), 1437-1446. doi:10.1002/cmdc.201800213
Peer Reviewed verified by ORBi

Iannelli, F., Santoro, F., Santagati, M., Docquier, J.-D., Lazzeri, E., Pastore, G., Cassone, M., Oggioni, M. R., Rossolini, G. M., Stefani, S., & Pozzi, G. (2018). Type M resistance to macrolides is due to a two-gene efflux transport system of the ATP-binding cassette (ABC) superfamily. Frontiers in Microbiology, 9, 1-9. doi:10.3389/fmicb.2018.01670
Peer Reviewed verified by ORBi

Pasero, C., D'Agostino, I., De Luca, F., Zamperini, C., Deodato, D., Truglio, G. I., Sannio, F., Del Prete, R., Ferraro, T., Visaggio, D., Mancini, A., Guglielmi, M. B., Visca, P., Docquier, J.-D., & Botta, M. (2018). Alkyl-guanidine Compounds as Potent Broad-Spectrum Antibacterial Agents: Chemical Library Extension and Biological Characterization. Journal of Medicinal Chemistry, 61 (20), 9162-9176. doi:10.1021/acs.jmedchem.8b00619
Peer Reviewed verified by ORBi

Docquier, J.-D., & Mangani, S. (2018). An update on β-lactamase inhibitor discovery and development. Drug Resistance Updates, 36, 13-29. doi:10.1016/j.drup.2017.11.002
Peer reviewed

Santucci, M., Spyrakis, F., Cross, S., Quotadamo, A., Farina, D., Tondi, D., De Luca, F., Docquier, J.-D., Prieto, A. I., Ibacache, C., Blázquez, J., Venturelli, A., Cruciani, G., & Costi, M. P. (2017). Computational and biological profile of boronic acids for the detection of bacterial serine- and metallo-β-lactamases. Scientific Reports, 7 (1). doi:10.1038/s41598-017-17399-7
Peer Reviewed verified by ORBi

Arouna, O., Deluca, F., Camara, M., Fall, B., Fall, B., Ba Diallo, A., Docquier, J.-D., & Mboup, S. (2017). Chryseobacterium gleum in a man with prostatectomy in Senegal: A case report and review of the literature. Journal of Medical Case Reports, 11 (1). doi:10.1186/s13256-017-1269-4
Peer Reviewed verified by ORBi

Lee, K., Yong, D., Jeong, S. H., Tulgaa, K., Docquier, J.-D., Rossolini, G. M., & Chong, Y. (2017). Genetic and biochemical characterisation of CTX-M-37 extended-spectrum β-lactamase from an Enterobacter cloacae clinical isolate from Mongolia. Journal of Global Antimicrobial Resistance, 10, 3-7. doi:10.1016/j.jgar.2017.03.007
Peer Reviewed verified by ORBi

Sevaille, L., Gavara, L., Bebrone, C., De Luca, F., Nauton, L., Achard, M., Mercuri, P., Tanfoni, S., Borgianni, L., Guyon, C., Lonjon, P., Turan-Zitouni, G., Dzieciolowski, J., Becker, K., Bénard, L., Condon, C., Maillard, L., Martinez, J., Frère, J.-M., ... Hernandez, J.-F. (2017). 1,2,4-Triazole-3-thione Compounds as Inhibitors of Dizinc Metallo-β-lactamases. ChemMedChem, 12, 972-985. doi:10.1002/cmdc.201700186
Peer Reviewed verified by ORBi

Zamperini, C., MacCari, G., Deodato, D., Pasero, C., D'Agostino, I., Orofino, F., De Luca, F., Dreassi, E., Docquier, J.-D., & Botta, M. (2017). Identification, synthesis and biological activity of alkyl-guanidine oligomers as potent antibacterial agents. Scientific Reports, 7 (1). doi:10.1038/s41598-017-08749-6
Peer Reviewed verified by ORBi

Maccari, G., Deodato, D., Fiorucci, D., Orofino, F., Truglio, G. I., Pasero, C., Martini, R., De Luca, F., Docquier, J.-D., & Botta, M. (2017). Design and synthesis of a novel inhibitor of T. Viride chitinase through an in silico target fishing protocol. Bioorganic and Medicinal Chemistry Letters, 27 (15), 3332-3336. doi:10.1016/j.bmcl.2017.06.016
Peer Reviewed verified by ORBi

Deodato, D., Maccari, G., De Luca, F., Sanfilippo, S., Casian, A., Martini, R., D'Arezzo, S., Bonchi, C., Bugli, F., Posteraro, B., Vandeputte, P., Sanglard, D., Docquier, J.-D., Sanguinetti, M., Visca, P., & Botta, M. (2016). Biological Characterization and in Vivo Assessment of the Activity of a New Synthetic Macrocyclic Antifungal Compound. Journal of Medicinal Chemistry, 59 (8), 3854-3866. doi:10.1021/acs.jmedchem.6b00018
Peer Reviewed verified by ORBi

Docquier, J.-D., & Mangani, S. (2016). Structure-Function Relationships of Class D Carbapenemases. Current Drug Targets, 17 (9), 1061-1071. doi:10.2174/1389450116666150825115824
Peer Reviewed verified by ORBi

Landini, G., Di Maggio, T., Sergio, F., Docquier, J.-D., Rossolini, G. M., & Pallecchi, L. (2016). Effect of high N-acetylcysteine concentrations on antibiotic activity against a large collection of respiratory pathogens. Antimicrobial Agents and Chemotherapy, 60 (12), 7513-7517. doi:10.1128/AAC.01334-16
Peer Reviewed verified by ORBi

Brindisi, M., Brogi, S., Giovani, S., Gemma, S., Lamponi, S., De Luca, F., Novellino, E., Campiani, G., Docquier, J.-D., & Butini, S. (2016). Targeting clinically-relevant metallo-β-lactamases: from high-throughput docking to broad-spectrum inhibitors. Journal of Enzyme Inhibition and Medicinal Chemistry, 31, 98-109. doi:10.3109/14756366.2016.1172575
Peer Reviewed verified by ORBi

Gudeta, D. D., Bortolaia, V., Pollini, S., Docquier, J.-D., Rossolini, G. M., Amos, G. C. A., Wellington, E. M. H., & Guardabassi, L. (2016). Expanding the repertoire of carbapenem-hydrolyzing metallo-β-lactamases by functional metagenomic analysis of soil microbiota. Frontiers in Microbiology, 7 (DEC). doi:10.3389/fmicb.2016.01985
Peer Reviewed verified by ORBi

Gudeta, D. D., Pollini, S., Docquier, J.-D., Bortolaia, V., Rossolini, G. M., & Guardabassi, L. (2016). Biochemical characterization of CPS-1, a subclass B3 metallo-β-lactamase from a Chryseobacterium piscium soil isolate. Antimicrobial Agents and Chemotherapy, 60 (3), 1869-1873. doi:10.1128/AAC.01924-15
Peer Reviewed verified by ORBi

Sgrignani, J., De Luca, F., Torosyan, H., Docquier, J.-D., Duan, D., Novati, B., Prati, F., Colombo, G., & Grazioso, G. (2016). Structure-based approach for identification of novel phenylboronic acids as serine-β-lactamase inhibitors. Journal of Computer-Aided Molecular Design, 30 (10), 851-861. doi:10.1007/s10822-016-9962-8
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Pozzi, C., De Luca, F., Benvenuti, M., Poirel, L., Nordmann, P., Rossolini, G. M., Mangani, S., & Docquier, J.-D. (2016). Crystal structure of the Pseudomonas aeruginosa BEL-1 extended-spectrum β-lactamase and its complexes with moxalactam and imipenem. Antimicrobial Agents and Chemotherapy, 60 (12), 7189-7199. doi:10.1128/AAC.00936-16
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Lahlaoui, H., De Luca, F., Maradel, S., Ben-Haj-Khalifa, A., Ben Hamouda, H., Kheder, M., Ben Moussa, M., Rossollini, G. M., & Docquier, J.-D. (2015). Occurrence of conjugative IncF-type plasmids harboring the bla CTX-M-15 gene in Enterobacteriaceae isolates from newborns in Tunisia. Pediatric Research, 77 (1), 107-110. doi:10.1038/pr.2014.153
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Papagiannitsis, C. C., Pollini, S., De Luca, F., Rossolini, G. M., Docquier, J.-D., & Hrabák, J. (2015). Biochemical characterization of VIM-39, a VIM-1-like metallo-β-lactamase variant from a multidrug-resistant Klebsiella pneumoniae isolate from Greece. Antimicrobial Agents and Chemotherapy, 59 (12), 7811-7814. doi:10.1128/AAC.01935-15
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Antonelli, A., D'Andrea, M. M., Vaggelli, G., Docquier, J.-D., & Rossolini, G. M. (2015). OXA-372, a novel carbapenem-hydrolysing class D β-lactamase from a Citrobacter freundii isolated from a hospital wastewater plant. Journal of Antimicrobial Chemotherapy, 70 (10), 2749-2756. doi:10.1093/jac/dkv181
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Lahiri, S. D., Mangani, S., Jahić, H., Benvenuti, M., Durand-Reville, T. F., De Luca, F., Ehmann, D. E., Rossolini, G. M., Alm, R. A., & Docquier, J.-D. (2015). Molecular basis of selective inhibition and slow reversibility of avibactam against class D carbapenemases: A structure-guided study of OXA-24 and OXA-48. ACS Chemical Biology, 10 (2), 591-600. doi:10.1021/cb500703p
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Borgianni, L., De Luca, F., Thaller, M. C., Chong, Y., Rossolini, G. M., & Docquier, J.-D. (2015). Biochemical characterization of the POM-1 metallo-β-lactamase from Pseudomonas otitidis. Antimicrobial Agents and Chemotherapy, 59 (3), 1755-1758. doi:10.1128/AAC.03843-14
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Docquier, J.-D., & Cusi, M. G. (2014). Editorial overview: Anti-infectives: Towards novel antiviral and antibacterial drugs? Current approaches to address a growing medical need. Current Opinion in Pharmacology, 18. doi:10.1016/j.coph.2014.10.004
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Maccari, G., Sanfilippo, S., De Luca, F., Deodato, D., Casian, A., Dasso Lang, M. C., Zamperini, C., Dreassi, E., Rossolini, G. M., Docquier, J.-D., & Botta, M. (2014). Synthesis of linear and cyclic guazatine derivatives endowed with antibacterial activity. Bioorganic and Medicinal Chemistry Letters, 24 (23), 5525-5529. doi:10.1016/j.bmcl.2014.09.081
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Lahiri, S. D., Mangani, S., Durand-Reville, T., Benvenuti, M., De Luca, F., Sanyal, G., & Docquier, J.-D. (2013). Structural insight into potent broad-spectrum inhibition with reversible recyclization mechanism: Avibactam in complex with CTX-M-15 and pseudomonas aeruginosa AmpC β-lactamases. Antimicrobial Agents and Chemotherapy, 57 (6), 2496-2505. doi:10.1128/AAC.02247-12
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Pollini, S., Maradei, S., Pecile, P., Olivo, G., Luzzaro, F., Docquier, J.-D., & Rossolini, G. M. (2013). FIM-1, a new acquired metallo-β-lactamase from a Pseudomonas aeruginosa clinical isolate from Italy. Antimicrobial Agents and Chemotherapy, 57 (1), 410-416. doi:10.1128/AAC.01953-12
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Docquier, J.-D., Rossolini, G. M., Nikaido, H., & Frère, J.-M. (2012). Interplay between beta-lactamase activity, outer membrane and active efflux system. In J.-M. Frère, Beta-Lactamases (pp. 401-418). New York, United States: Nova Science Publishers, Inc.

Gualdi, L., Hayre, J. K., Gerlini, A., Bidossi, A., Colomba, L., Trappetti, C., Pozzi, G., Docquier, J.-D., Andrew, P., Ricci, S., & Oggioni, M. R. (2012). Regulation of neuraminidase expression in Streptococcus pneumoniae. BMC Microbiology, 12. doi:10.1186/1471-2180-12-200
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Hayre, J. K., Xu, G., Borgianni, L., Taylor, G. L., Andrew, P. W., Docquier, J.-D., & Oggioni, M. R. (2012). Optimization of a direct spectrophotometric method to investigate the kinetics and inhibition of sialidases. BMC Biochemistry, 13 (1). doi:10.1186/1471-2091-13-19
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Lassaux, P., Traoré, D., Loisel, E., Favier, A., Docquier, J.-D., Sohier, J., Laurent, C., Bebrone, C., Frère, J.-M., Ferrer, J.-L., & Galleni, M. (2011). Biochemical and structural characterization of the subclass B1 metallo-β-lactamase VIM-4. Antimicrobial Agents and Chemotherapy. doi:10.1128/AAC.01486-09
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Santella, G., Pollini, S., Docquier, J.-D., Almuzara, M., Gutkind, G., Rossolini, G. M., & Radice, M. (2011). Resistencia a carbapenemes en aislamientos de Pseudomonas aeruginosa: Un ejemplo de interacción entre distintos mecanismos. Revista Panamericana de Salud Publica/Pan American Journal of Public Health, 30 (6), 545-548. doi:10.1590/S1020-49892011001200008
Peer reviewed

Docquier, J.-D., Benvenuti, M., Calderone, V., Rossolini, G.-M., & Mangani, S. (2011). Structure of the extended-spectrum β-lactamase TEM-72 inhibited by citrate. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications, 67 (3), 303-306. doi:10.1107/S1744309110054680
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Lee, K., Yum, J. H., Yong, D., Jeong, S. H., Rossolini, G. M., Docquier, J.-D., & Chong, Y. (2011). Biochemical characterization of the TEM-107 extended-spectrum β-lactamase in a Klebsiella pneumoniae isolate from South Korea. Antimicrobial Agents and Chemotherapy, 55 (12), 5930-5932. doi:10.1128/AAC.05341-11
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De Luca, F., Benvenuti, M., Carboni, F., Pozzi, C., Rossolini, G. M., Mangani, S., & Docquier, J.-D. (2011). Evolution to carbapenem-hydrolyzing activity in noncarbapenemase class D β-lactamase OXA-10 by rational protein design. Proceedings of the National Academy of Sciences of the United States of America, 108 (45), 18424-18429. doi:10.1073/pnas.1110530108
Peer Reviewed verified by ORBi

Santella, G., Docquier, J.-D., Gutkind, G., Rossolini, G. M., & Radice, M. (2011). Purification and biochemical characterization of IMP-13 metallo-β-lactamase. Antimicrobial Agents and Chemotherapy, 55 (1), 399-401. doi:10.1128/AAC.00421-10
Peer Reviewed verified by ORBi

Borgianni, L., Prandi, S., Salden, L., Santella, G., Hanson, N. D., Rossolini, G. M., & Docquier, J.-D. (2011). Genetic context and biochemical characterization of the IMP-18 metallo-β-lactamase identified in a Pseudomonas aeruginosa isolate from the United States. Antimicrobial Agents and Chemotherapy, 55 (1), 140-145. doi:10.1128/AAC.00858-10
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Docquier, J.-D., Benvenuti, M., Calderone, V., Giuliani, F., Kapetis, D., De Luca, F., Rossolini, G. M., & Mangani, S. (2010). Crystal structure of the narrow-spectrum OXA-46 class D β-lactamase: Relationship between active-site lysine carbamylation and inhibition by polycarboxylates. Antimicrobial Agents and Chemotherapy, 54 (5), 2167-2174. doi:10.1128/AAC.01517-09
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Santella, G., Pollini, S., Docquier, J.-D., Mereuta, A. I., Gutkind, G., Rossolini, G. M., & Radice, M. (2010). Intercontinental dissemination of IMP-13-producing Pseudomonas aeruginosa belonging in sequence type 621. Journal of Clinical Microbiology, 48 (11), 4342-4343. doi:10.1128/JCM.00614-10
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Borgianni, L., Vandenameele, J., Matagne, A., Bini, L., Bonomo, R. A., Frère, J.-M., Rossolini, G. M., & Docquier, J.-D. (2010). Mutational analysis of VIM-2 reveals an essential determinant for metallo-beta-lactamase stability and folding. Antimicrobial Agents and Chemotherapy, 54 (8), 3197-204. doi:10.1128/AAC.01336-09
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Docquier, J.-D., Benvenuti, M., Calderone, V., Stoczko, M., Menciassi, N., Rossolini, G. M., & Mangani, S. (2010). High-resolution crystal structure of the subclass B3 metallo-β- lactamase BJP-1: Rational basis for substrate specificity and interaction with sulfonamides. Antimicrobial Agents and Chemotherapy, 54 (10), 4343-4351. doi:10.1128/AAC.00409-10
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De Luca, F., Giraud-Morin, C., Rossolini, G. M., Docquier, J.-D., & Fosse, T. (2010). Genetic and biochemical characterization of TRU-1, the endogenous class C β-lactamase from Aeromonas enteropelogenes. Antimicrobial Agents and Chemotherapy, 54 (4), 1547-1554. doi:10.1128/AAC.01252-09
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Poirel, L., Docquier, J.-D., De Luca, F., Verlinde, A., Ide, L., Rossolini, G. M., & Nordmann, P. (2010). BEL-2, an extended-spectrum β-lactamase with increased activity toward expanded-spectrum cephalosporins in Pseudomonas aeruginosa. Antimicrobial Agents and Chemotherapy, 54 (1), 533-535. doi:10.1128/AAC.00859-09
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Lee, K., Kim, C. K., Hong, S. G., Choi, J., Song, S., Koh, E., Yong, D., Jeong, S. H., Yum, J. H., Docquier, J.-D., Rossolini, G. M., & Chong, Y. (2010). Characteristics of clinical isolates of Acinetobacter genomospecies 10 carrying two different metallo-β-lactamases. International Journal of Antimicrobial Agents, 36 (3), 259-263. doi:10.1016/j.ijantimicag.2010.05.018
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Lee, K., Kim, C. K., Yong, D., Jeong, S. H., Yum, J. H., Seo, Y. H., Docquier, J.-D., & Chong, Y. (2010). Improved performance of the modified Hodge test with MacConkey agar for screening carbapenemase-producing Gram-negative bacilli. Journal of Microbiological Methods, 83 (2), 149-152. doi:10.1016/j.mimet.2010.08.010
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Docquier, J.-D., Calderone, V., De Luca, F., Benvenuti, M., Giuliani, F., Bellucci, L., Tafi, A., Nordmann, P., Botta, M., Rossolini, G. M., & Mangani, S. (2009). Crystal Structure of the OXA-48 β-Lactamase Reveals Mechanistic Diversity among Class D Carbapenemases. Chemistry and Biology, 16 (5), 540-547. doi:10.1016/j.chembiol.2009.04.010
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Zeba, B., De Luca, F., Dubus, A., Delmarcelle, M., Simporé, J., Nacoulma, O. G., Rossolini, G. M., Frère, J.-M., & Docquier, J.-D. (2009). IND-6, a Highly Divergent IND-type Metallo-{beta}-lactamase from Chryseobacterium indologenes strain 597 isolated in Burkina Faso. Antimicrobial Agents and Chemotherapy. doi:10.1128/AAC.01607-08
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MEEX, C., MELIN, P., Docquier, J.-D., Kabasele, T., HUYNEN, P., Tulkens, P., Giet, D., & De Mol, P. (2008). Presenec of extended-spectrum beta-lactamase-producing Enterobacteriaceae in the fecal flora of patients from general practice. In ECCMID (Ed.), Program and Abstracts book of the 18th ECCMID.
Peer reviewed

Garcia-Saez, I., Docquier, J.-D., Rossolini, G. M., & Dideberg, O. (2008). The Three-Dimensional Structure of VIM-2, a Zn-β-Lactamase from Pseudomonas aeruginosa in Its Reduced and Oxidised Form. Journal of Molecular Biology, 375 (3), 604-611. doi:10.1016/j.jmb.2007.11.012
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Stoczko, M., Frère, J.-M., Rossolini, G. M., & Docquier, J.-D. (2008). Functional diversity among metallo-β-lactamases: Characterization of the CAR-1 enzyme of Erwinia carotovora. Antimicrobial Agents and Chemotherapy, 52 (7), 2473-2479. doi:10.1128/AAC.01062-07
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Gori Savellini, G., Di Genova, G., Terrosi, C., Di Bonito, P., Giorgi, C., Valentini, M., Docquier, J.-D., & Cusi, M. G. (2008). Immunization with Toscana virus N-Gc proteins protects mice against virus challenge. Virology, 375 (2), 521-528. doi:10.1016/j.virol.2008.02.006
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Michaux, C., Massant, J., Kerff, F., Frère, J.-M., Docquier, J.-D., Vandenberghe, I., Samyn, B., Pierrard, A., Feller, G., Charlier, P., Van Beeumen, J., & Wouters, J. (2008). Crystal structure of a cold-adapted class C beta-lactamase. FEBS Journal, 275 (8), 1687-97. doi:10.1111/j.1742-4658.2008.06324.x
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Cagnacci, S., Gualco, L., Roveta, S., Mannelli, S., Borgianni, L., Docquier, J.-D., Dodi, F., Centanaro, M., Debbia, E., Marchese, A., & Rossolini, G. M. (2008). Bloodstream infections caused by multidrug-resistant Klebsiella pneumoniae producing the carbapenem-hydrolysing VIM-1 metallo-β-lactamase: First Italian outbreak. Journal of Antimicrobial Chemotherapy, 61 (2), 296-300. doi:10.1093/jac/dkm471
Peer Reviewed verified by ORBi

Cornaglia, G., Akova, M., Amicosante, G., Canton, R., Cauda, R., Docquier, J.-D., Edelstein, M., Frère, J.-M., Fuzi, M., Galleni, M., Giamarellou, H., Gniadkowski, M., Koncan, R., Libisch, B., Luzzaro, F., Miriagou, V., Navarro, F., Nordmann, P., Pagani, L., ... Rossolini, G. M. (April 2007). Metallo-beta-lactamases as emerging resistance determinants in Gram-negative pathogens: open issues. International Journal of Antimicrobial Agents, 29 (4), 380-388. doi:10.1016/j.ijantimicag.2006.10.008
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Docquier, J.-D., & Rossolini, G. M. (2007). Class B β-Lactamases. In R. A. Bonomo & M. Tolmasky, Enzyme-Mediated Resistance to Antibiotics. Mechanisms, Dissemination and Prospects for Inhibition (pp. 115-144). Washington, United States: ASM Press.

Zeba, B., Kiendrébeogo, M., Lamien, A., Docquier, J.-D., Simporé, J., & Nacoulma, O. G. (2007). Major enzymatic factors involved in bacterial penicillin resistance in Burkina Faso. Pakistan Journal of Biological Sciences, 10 (3), 506-510. doi:10.3923/pjbs.2007.506.510
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Rossolini, G. M., Mantengoli, E., Docquier, J.-D., Musmanno, R. A., & Coratza, G. (2007). Epidemiology of infections caused by multiresistant Gram-negatives: ESBLs, MBLs, panresistant strains. New Microbiologica, 30 (3), 332-339.
Peer Reviewed verified by ORBi

Perilli, M., Caporale, B., Celenza, G., Pellegrini, C., Docquier, J.-D., Mezzatesta, M., Rossolini, G. M., Stefani, A., & Amicosante, G. (2007). Identification and characterization of a new metallo-β-lactamase, IND-5, from a clinical isolate of Chryseobacterium indologenes. Antimicrobial Agents and Chemotherapy, 51 (8), 2988-2990. doi:10.1128/AAC.00083-07
Peer Reviewed verified by ORBi

CHRISTIAENS, G., Damas, P., Docquier, J.-D., HAYETTE, M.-P., MELIN, P., & De Mol, P. (2006). Molecular epidemiology of extended-spectrum beta-lactamase-producing Enterobacteriaceae colonizing the digestive tract of patients admitted to intensive care units in a Belgian university hospital. In American Society of Microbiology (Ed.), Program and Abstracts of the 46th Intersciences Conference on Antimicrobial Agents and Chemotherapy (pp. 2-105). Washington, United States: American Society for Microbiology (ASM).
Peer reviewed

Stoczko, M., Frère, J.-M., Rossolini, G. M., & Docquier, J.-D. (2006). Postgenomic scan of metallo-β-lactamase homologues in rhizobacteria: Identification and characterization of BJP-1, a subclass B3 ortholog from Bradyrhizobium japonicum. Antimicrobial Agents and Chemotherapy, 50 (6), 1973-1981. doi:10.1128/AAC.01551-05
Peer Reviewed verified by ORBi

Rossolini, G. M., & Docquier, J.-D. (2006). New β-lactamases: A paradigm for the rapid response of bacterial evolution in the clinical setting. Future Microbiology, 1 (3), 295-308. doi:10.2217/17460913.1.3.295
Peer Reviewed verified by ORBi

Voha, C., Docquier, J.-D., Rossolini, G. M., & Fosse, T. (2006). Genetic and biochemical characterization of FUS-1 (OXA-85), a narrow-spectrum class D β-lactamase from Fusobacterium nucleatum subsp. polymorphum. Antimicrobial Agents and Chemotherapy, 50 (8), 2673-2679. doi:10.1128/AAC.00058-06
Peer Reviewed verified by ORBi

Lee, K., Yum, J. H., Yong, D., Lee, H. M., Kim, H. D., Docquier, J.-D., Rossolini, G. M., & Chong, Y. (2005). Novel acquired metallo-β-lactamase gene, blaSIM-1, in a class 1 integron from Acinetobacter baumannii clinical isolates from Korea. Antimicrobial Agents and Chemotherapy, 49 (11), 4485-4491. doi:10.1128/AAC.49.11.4485-4491.2005
Peer Reviewed verified by ORBi

Giuliani, F., Docquier, J.-D., Riccio, M. L., Pagani, L., & Rossolini, G. M. (2005). OXA-46, a new class D β-lactamase of narrow substrate specificity encoded by a blaVIM-1-containing integron from a Pseudomonas aeruginosa clinical isolate. Antimicrobial Agents and Chemotherapy, 49 (5), 1973-1980. doi:10.1128/AAC.49.5.1973-1980.2005
Peer Reviewed verified by ORBi

Pagani, L., Colinon, C., Migliavacca, R., Labonia, M., Docquier, J.-D., Nucleo, E., Spalla, M., Bergoli, M. L., & Rossolini, G. M. (2005). Nosocomial outbreak caused by multidrug-resistant Pseudomonas aeruginosa producing IMP-13 metallo-β-lactamase. Journal of Clinical Microbiology, 43 (8), 3824-3828. doi:10.1128/JCM.43.8.3824-3828.2005
Peer Reviewed verified by ORBi

Riccio, M. L., Pallecchi, L., Docquier, J.-D., Cresti, S., Catania, M. R., Pagani, L., Lagatolla, C., Cornaglia, G., Fontana, R., & Rossolini, G. M. (2005). Clonal relatedness and conserved integron structures in epidemiologically unrelated Pseudomonas aeruginosa strains producing the VIM-1 metallo-β-lactamase from different Italian hospitals. Antimicrobial Agents and Chemotherapy, 49 (1), 104-110. doi:10.1128/AAC.49.1.104-110.2005
Peer Reviewed verified by ORBi

Luzzaro, F., Endimiani, A., Docquier, J.-D., Mugnaioli, C., Bonsignori, M., Amicosante, G., Rossolini, G. M., & Toniolo, A. (2004). Prevalence and characterization of metallo-β-lactamases in clinical isolates of Pseudomonas aeruginosa. Diagnostic Microbiology and Infectious Disease, 48 (2), 131-135. doi:10.1016/j.diagmicrobio.2003.09.005
Peer Reviewed verified by ORBi

Docquier, J.-D., Lopizzo, T., Liberatori, S., Prenna, M., Thaller, M. C., Frère, J.-M., & Rossolini, G. M. (2004). Biochemical characterization of the THIN-B metallo-β-lactamase of Janthinobacterium lividum. Antimicrobial Agents and Chemotherapy, 48 (12), 4778-4783. doi:10.1128/AAC.48.12.4778-4783.2004
Peer Reviewed verified by ORBi

Luzzaro, F., Docquier, J.-D., Colinon, C., Endimiani, A., Lombardi, G., Amicosante, G., Rossolini, G. M., & Toniolo, A. (2004). Emergence in Klebsiella pneumoniae and Enterobacter cloacae Clinical Isolates of the VIM-4 Metallo-β-Lactamase Encoded by a Conjugative Plasmid. Antimicrobial Agents and Chemotherapy, 48 (2), 648-650. doi:10.1128/AAC.48.2.648-650.2004
Peer Reviewed verified by ORBi

Docquier, J.-D., Lamotte-Brasseur, J., Galleni, M., Amicosante, G., Frère, J.-M., & Rossolini, G. M. (February 2003). On functional and structural heterogeneity of VIM-type metallo-beta-lactamases. Journal of Antimicrobial Chemotherapy, 51 (2), 257-266. doi:10.1093/jac/dkg067
Peer Reviewed verified by ORBi

Docquier, J.-D., Riccio, M. L., Mugnaioli, C., Luzzaro, F., Endimiani, A., Toniolo, A., Amicosante, G., & Rossolini, G. M. (2003). IMP-12, a new plasmid-encoded metallo-β-lactamase from a Pseudomonas putida clinical isolate. Antimicrobial Agents and Chemotherapy, 47 (5), 1522-1528. doi:10.1128/AAC.47.5.1522-1528.2003
Peer Reviewed verified by ORBi

Forleo, C., Benvenuti, M., Calderone, V., Schippa, S., Docquier, J.-D., Cristina Thaller, M., Rossolini, G. M., & Mangani, S. (2003). Expression, purification, crystallization and preliminary X-ray characterization of the class B acid phosphatase (AphA) from Escherichia coli. Acta Crystallographica. Section D, Biological Crystallography, 59 (6), 1058-1060. doi:10.1107/S0907444903006826
Peer Reviewed verified by ORBi

Riccio, M. L., Docquier, J.-D., Dell'Amico, E., Luzzaro, F., Amicosante, G., & Rossolini, G. M. (2003). Novel 3-N-aminoglycoside acetyltransferase gene, aac(3)-Ic, from a Pseudomonas aeruginosa integron. Antimicrobial Agents and Chemotherapy, 47 (5), 1746-1748. doi:10.1128/AAC.47.5.1746-1748.2003
Peer Reviewed verified by ORBi

Vessillier, S., Docquier, J.-D., Rival, S., Frère, J.-M., Galleni, M., Amicosante, G., Rossolini, G. M., & Franceschini, N. (June 2002). Overproduction and biochemical characterization of the Chryseobacterium meningosepticum BlaB metallo-beta-lactamase. Antimicrobial Agents and Chemotherapy, 46 (6), 1921-1927. doi:10.1128/AAC.46.6.1921-1927.2002
Peer Reviewed verified by ORBi

Docquier, J.-D., Pantanella, F., Giuliani, F., Thaller, M. C., Amicosante, G., Galleni, M., Frère, J.-M., Bush, K., & Rossolini, G. M. (June 2002). CAU-1, a subclass B3 metallo-beta-lactamase of low substrate affinity encoded by an ortholog present in the Caulobacter crescentus chromosome. Antimicrobial Agents and Chemotherapy, 46 (6), 1823-1830. doi:10.1128/AAC.46.6.1823-1830.2002
Peer Reviewed verified by ORBi

Migliavacca, R., Docquier, J.-D., Mugnaioli, C., Amicosante, G., Daturi, R., Lee, K., Rossolini, G. M., & Pagani, L. (2002). Simple microdilution test for detection of metallo-β-lactamase production in pseudomonas aeruginosa. Journal of Clinical Microbiology, 40 (11), 4388-4390. doi:10.1128/JCM.40.11.4388-4390.2002
Peer Reviewed verified by ORBi

Lombardi, G., Luzzaro, F., Docquier, J.-D., Riccio, M. L., Perilli, M., Colì, A., Amicosante, G., Rossolini, G. M., & Toniolo, A. (2002). Nosocomial infections caused by multidrug-resistant isolates of Pseudomonas putida producing VIM-1 metallo-β-lactamase. Journal of Clinical Microbiology, 40 (11), 4051-4055. doi:10.1128/JCM.40.11.4051-4055.2002
Peer Reviewed verified by ORBi

Bebrone, C., Moali, C., Mahy, F., Rival, S., Docquier, J.-D., Rossolini, G. M., Fastrez, J., Pratt, R. F., Frère, J.-M., & Galleni, M. (June 2001). Centa as a Chromogenic Substrate for Studying Beta-Lactamases. Antimicrobial Agents and Chemotherapy, 45 (6), 1868-71. doi:10.1128/AAC.45.6.1868-1871.2001
Peer Reviewed verified by ORBi

Duez, C., Vanhove, M., Gallet, X., Bouillenne, F., Docquier, J.-D., Brans, A., & Frère, J.-M. (March 2001). Purification and Characterization of Pbp4a, a New Low-Molecular-Weight Penicillin-Binding Protein from Bacillus subtilis. Journal of Bacteriology, 183 (5), 1595-9. doi:10.1128/JB.183.5.1595-1599.2001
Peer Reviewed verified by ORBi

Pallecchi, L., Riccio, M. L., Docquier, J.-D., Fontana, R., & Rossolini, G. M. (2001). Molecular heterogeneity of blaVIM-2-containing integrons from Pseudomonas aeruginosa plasmids encoding the VIM-2 metallo-β-lactamase. FEMS Microbiology Letters, 195 (2), 145-150. doi:10.1016/S0378-1097(01)00002-7
Peer Reviewed verified by ORBi

Docquier, J.-D., Luzzaro, F., Amicosante, G., Toniolo, A., & Rossolini, G. M. (2001). Multidrug-resistant Pseudomonas aeruginosa producing PER-1 extended-spectrum serine-β-lactamase and VIM-2 metallo-β-lactamase [letter to the editor]. Emerging Infectious Diseases, 7 (5), 910-911. doi:10.3201/eid0705.010528
Peer Reviewed verified by ORBi

Rossolini, G. M., Condemi, M. A., Pantanella, F., Docquier, J.-D., Amicosante, G., & Thaller, M. C. (2001). Metallo-β-lactamase producers in environmental microbiota: New molecular class B enzyme in Janthinobacterium lividum. Antimicrobial Agents and Chemotherapy, 45 (3), 837-844. doi:10.1128/AAC.45.3.837-844.2001
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Franceschini, N., Caravelli, B., Docquier, J.-D., Galleni, M., Frère, J.-M., Amicosante, G., & Rossolini, G. M. (2000). Purification and biochemical characterization of the VIM-1 metallo-beta-lactamase. Antimicrobial Agents and Chemotherapy, 44 (11), 3003-7. doi:10.1128/AAC.44.11.3003-3007.2000
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Pierrard, A., Ledent, P., Docquier, J.-D., Feller, G., Gerday, C., & Frère, J.-M. (1998). Inducible class C beta-lactamases produced by psychrophilic bacteria. FEMS Microbiology Letters, 161, 311-315. doi:10.1016/S0378-1097(98)00088-3
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