Life sciences: Multidisciplinary, general & others Microbiology
Author, co-author :
Deodato, D.; Department of Biotechnology Chemistry and Pharmacy, University of Siena, Siena, I-53100, Italy, Lead Discovery Siena S.r.l., Via Vittorio Alfieri 31, Castelnuovo Berardenga, I-53019, Italy
Maccari, G.; Department of Biotechnology Chemistry and Pharmacy, University of Siena, Siena, I-53100, Italy, Lead Discovery Siena S.r.l., Via Vittorio Alfieri 31, Castelnuovo Berardenga, I-53019, Italy
De Luca, F.; Department of Medical Biotechnology, University of Siena, Siena, I-53100, Italy
Sanfilippo, S.; Department of Biotechnology Chemistry and Pharmacy, University of Siena, Siena, I-53100, Italy
Casian, A.; Department of Biotechnology Chemistry and Pharmacy, University of Siena, Siena, I-53100, Italy
Martini, R.; Department of Biotechnology Chemistry and Pharmacy, University of Siena, Siena, I-53100, Italy
D'Arezzo, S.; Istituto Nazionale per le Malattie Infettive Lazzaro Spallanzani, Roma, I-00149, Italy
Bonchi, C.; Dipartimento di Scienze, Università Roma Tre, Roma, I-00154, Italy
Bugli, F.; Institute of Microbiology, Università Cattolica Del Sacro Cuore, Roma, I-00168, Italy
Posteraro, B.; Institute of Public Health, Università Cattolica Del Sacro Cuore, Roma, I-00168, Italy
Vandeputte, P.; Institute of Microbiology, University of Lausanne, University Hospital Center, Lausanne, CH-1011, Switzerland
Sanglard, D.; Institute of Microbiology, University of Lausanne, University Hospital Center, Lausanne, CH-1011, Switzerland
Docquier, Jean-Denis ; Université de Liège - ULiège > Département des sciences de la vie > Centre d'ingénierie des protéines
Sanguinetti, M.; Institute of Microbiology, Università Cattolica Del Sacro Cuore, Roma, I-00168, Italy, Institute of Public Health, Università Cattolica Del Sacro Cuore, Roma, I-00168, Italy
Visca, P.; Dipartimento di Scienze, Università Roma Tre, Roma, I-00154, Italy
Botta, M.; Department of Biotechnology Chemistry and Pharmacy, University of Siena, Siena, I-53100, Italy, Sbarro Institute for Cancer Research and Molecular Medicine, Temple University, BioLife Science Building, 1900 North 12th Street, Philadelphia, PA 19122, United States, Lead Discovery Siena S.r.l., Via Vittorio Alfieri 31, Castelnuovo Berardenga, I-53019, Italy
Arendrup, M. C. Candida and Candidaemia. Susceptibility and Epidemiology Dan. Med. J. 2013, 60, 4698
Morschhäuser, J. Regulation of Multidrug Resistance in Pathogenic Fungi Fungal Genet. Biol. 2010, 47, 94-106 10.1016/j.fgb.2009.08.002
Pfaller, M. A.; Messer, S. A.; Moet, G. J.; Jones, R. N.; Castanheira, M. Candida Bloodstream Infections: Comparison of Species Distribution and Resistance to Echinocandin and Azole Antifungal Agents in Intensive Care Unit (ICU) and Non-ICU Settings in the SENTRY Antimicrobial Surveillance Program (2008-2009) Int. J. Antimicrob. Agents 2011, 38, 65-69 10.1016/j.ijantimicag.2011.02.016
Groll, A. H.; Lumb, J. New Developments in Invasive Fungal Disease Future Microbiol. 2012, 7, 179-184 10.2217/fmb.11.154
Alexander, B. D.; Johnson, M. D.; Pfeiffer, C. D.; Jiménez-Ortigosa, C.; Catania, J.; Booker, R.; Castanheira, M.; Messer, S. A.; Perlin, D. S.; Pfaller, M. A. Increasing Echinocandin Resistance in Candida Glabrata: Clinical Failure Correlates with Presence of FKS Mutations and Elevated Minimum Inhibitory Concentrations Clin. Infect. Dis. 2013, 56, 1724-1732 10.1093/cid/cit136
Bizerra, F. C.; Jimenez-Ortigosa, C.; Souza, A. C.; Breda, G.; Queiroz-Telles, F.; Perlin, D. S.; Colombo, A. L. Breakthrough Candidemia Due to Multidrug-Resistant Candida Glabrata during Prophylaxis with a Low Dose of Micafungin Antimicrob. Agents Chemother. 2014, 58, 2438-2440 10.1128/AAC.02189-13
Sternberg, S. The Emerging Fungal Threat Science 1994, 266, 1632-1634 10.1126/science.7702654
Pappas, P. G.; Rex, J. H.; Lee, J.; Hamill, R. J.; Larsen, R. A.; Powderly, W.; Kauffman, C. A.; Hyslop, N.; Mangino, J. E.; Chapman, S.; Horowitz, H. W.; Edwards, J. E.; Dismukes, W. E. NIAID Mycoses Study Group. A Prospective Observational Study of Candidemia: Epidemiology, Therapy, and Influences on Mortality in Hospitalized Adult and Pediatric Patients Clin. Infect. Dis. 2003, 37, 634-643 10.1086/376906
Klepser, M. E. Candida Resistance and its Clinical Relevance Pharmacotherapy 2006, 26, 68-75 10.1592/phco.26.6part2.68S
Ahmad, A.; Khan, A.; Manzoor, N. Reversal of Efflux Mediated Antifungal Resistance Underlies Synergistic Activity of two Monoterpenes with Fluconazole Eur. J. Pharm. Sci. 2013, 48, 80-86 10.1016/j.ejps.2012.09.016
Castagnolo, D.; Raffi, F.; Giorgi, G.; Botta, M. Macrocyclization of Di-Boc-guanidino-alkylamines Related to Guazatine Components: Discovery and Synthesis of Innovative Macrocyclic Amidinoureas Eur. J. Org. Chem. 2009, 3, 334-337 10.1002/ejoc.200801109
Dreassi, E.; Zizzari, A. T.; D'Arezzo, S.; Visca, P.; Botta, M. Analysis of Guazatine Mixture by LC and LC-MS and Antimycotic Activity Determination of Principal Components J. Pharm. Biomed. Anal. 2007, 43, 1499-1506 10.1016/j.jpba.2006.10.029
Raffi, F.; Corelli, F.; Botta, M. Efficient Synthesis of Iminoctadine, a Potent Antifungal Agent and Polyamine Oxidase Inhibitor (PAO) Synthesis 2007, 19, 3013-3016 10.1055/s-2007-983898
Manetti, F.; Castagnolo, D.; Raffi, F.; Zizzari, A. T.; Rajamäki, S.; D'Arezzo, S.; Visca, P.; Cona, A.; Fracasso, M. A.; Doria, D.; Posteraro, B.; Sanguinetti, M.; Fadda, G.; Botta, M. Synthesis of New Linear Guanidines and Macrocyclic Amidinourea Derivatives Endowed with High Antifungal Activity against Candida spp. and Aspergillus spp J. Med. Chem. 2009, 52, 7376-7379 10.1021/jm900760k
Castagnolo, D.; Schenone, S.; Botta, M. Guanylated Diamines, Triamines, and Polyamines: Chemistry and Biological Properties Chem. Rev. 2011, 111, 5247-5300 10.1021/cr100423x
Sanguinetti, M.; Sanfilippo, S.; Castagnolo, D.; Sanglard, D.; Posteraro, B.; Donzellini, G.; Botta, M. Novel Macrocyclic Amidinoureas: Potent Non-Azole Antifungals Active against Wild-Type and Resistant Candida Species ACS Med. Chem. Lett. 2013, 4, 852-857 10.1021/ml400187w
Sanfilippo, S.; Posteraro, B.; Sanguinetti, M.; Botta, M.; Maccari, G.; De Luca, F.; Docquier, J. D.; Deodato, D. New Macrocyclic Amidinourea, Methods of Preparation and Uses Thereof as Chitinase Inhibitors. Int. Patent Appl. WO/2014/202697A1, 2014.
Botta, M.; Raffi, F.; Visca, P. Linear and Cyclic Guanidine Derivatives, Method of Preparation and Uses Thereof. Int. Patent Appl. WO/2009/113033A2, 2009.
Maccari, G.; Sanfilippo, S.; De Luca, F.; Deodato, D.; Casian, A.; Dasso Lang, M. C.; Zamperini, C.; Dreassi, E.; Rossolini, G. M.; Docquier, J. D.; Botta, M. Synthesis of Linear and Cyclic Guazatine Derivatives Endowed with Antibacterial Activity Bioorg. Med. Chem. Lett. 2014, 24, 5525-5529 10.1016/j.bmcl.2014.09.081
Putignani, L.; Paglia, M. G.; Bordi, E.; Nebuloso, E.; Pucillo, L. P.; Visca, P. Identification of Clinically Relevant Yeast Species by DNA Sequence Analysis of the D2 Variable Region of the 25-28S rRNA Gene Mycoses 2008, 51, 209-227 10.1111/j.1439-0507.2007.01472.x
Coste, A. T.; Karababa, M.; Ischer, F.; Bille, J.; Sanglard, D. TAC1, Transcriptional Activator of CDR Genes, is a New Transcription Factor Involved in the Regulation of Candida Albicans ABC Transporters CDR1 and CDR2 Eukaryotic Cell 2004, 3, 1639-1652 10.1128/EC.3.6.1639-1652.2004
De Micheli, M.; Bille, J.; Schueller, C.; Sanglard, D. A Common Drug-Responsive Element Mediates the Upregulation of the Candida Albicans ABC Transporters CDR1 and CDR2, Two Genes Involved in Antifungal Drug Resistance Mol. Microbiol. 2002, 43, 1197-1214 10.1046/j.1365-2958.2002.02814.x
Sanglard, D.; Ischer, F.; Monod, M.; Bille, J. Cloning of Candida Albicans Genes Conferring Resistance to Azole Antifungal Agents: Characterization of CDR2, a New Multidrug ABC Transporter Gene Microbiology 1997, 143, 405-416 10.1099/00221287-143-2-405
Sun, N.; Li, D.; Fonzi, W.; Li, X.; Zhang, L.; Calderone, L. Multidrug-Resistant Transporter Mdr1p-Mediated Uptake of a Novel Antifungal Compound Antimicrob. Agents Chemother. 2013, 57, 5931-5939 10.1128/AAC.01504-13
MacCallum, D. M.; Coste, A.; Ischer, F.; Jacobsen, M. D.; Odds, F. C.; Sanglard, D. Genetic Dissection of Azole Resistance Mechanisms in Candida Albicans and their Validation in a Mouse Model of Disseminated Infection Antimicrob. Agents Chemother. 2010, 54, 1476-1483 10.1128/AAC.01645-09
Rodriguez-Tudela, J. L.; Arendrup, M. C.; Barchiesi, F.; Bille, J.; Chryssanthou, E.; Cuenca-Estrella, M.; Dannaoui, E.; Denning, D. W.; Donnelly, J. P.; Dromer, F.; Fegeler, W.; Lass-Flörl, C.; Moore, C.; Richardson, M.; Sandven, P.; Velegraki, A.; Verweij, P. EUCAST Definitive Document EDef 7.1: Method for the Determination of Broth Dilution MICs of Antifungal Agents for Fermentative Yeasts: Subcommittee on Antifungal Susceptibility Testing (AFST) of the ESCMID European Committee for Antimicrobial Susceptibility Testing (EUCAST) Clin. Microbiol. Infect. 2008, 14, 398-405 10.1111/j.1469-0691.2007.01935.x
Arendrup, M. C.; Cuenca-Estrella, M.; Lass-Flörl, C.; Hope, W. EUCAST Technical Note on the EUCAST Definitive Document EDef 7.2: Method for the Determination of Broth Dilution Minimum Inhibitory Concentrations of Antifungal Agents for Yeasts EDef 7.2 (EUCAST-AFST) Clin. Microbiol. Infect. 2012, 18, 246-247 10.1111/j.1469-0691.2012.03880.x
National Committee for Clinical Laboratory Standards. Methods for Determining Bactericidal Activity of Antimicrobial Agents, Approved Guideline, Document M26-A; National Committee for Clinical Laboratory Standards: Wayne, PA, 1999.
Pfaller, M. A.; Sheehan, D. J.; Rex, J. H. Determination of Fungicidal Activities against Yeasts and Molds: Lessons Learned from Bactericidal Testing and the Need for Standardization Clin. Microbiol. Rev. 2004, 17, 268-280 10.1128/CMR.17.2.268-280.2004
Sanglard, D.; Ischer, F.; Bille, J. Role of ATP-Binding-Cassette Transporter Genes in High-Frequency Acquisition of Resistance to Azole Antifungals in Candida Glabrata Antimicrob. Agents Chemother. 2001, 45, 1174-1183 10.1128/AAC.45.4.1174-1183.2001
Synnott, J. M.; Guida, A.; Mulhern-Haughey, S.; Higgins, D. G.; Butler, G. Regulation of the Hypoxic Response in Candida Albicans Eukaryotic Cell 2010, 9, 1734-1746 10.1128/EC.00159-10
Sanguinetti, M.; Posteraro, B.; Fiori, B.; Ranno, S.; Torelli, R.; Fadda, G. Mechanisms of Azole Resistance in Clinical Isolates of Candida Glabrata Collected During a Hospital Survey of Antifungal Resistance Antimicrob. Agents Chemother. 2005, 49, 668-679 10.1128/AAC.49.2.668-679.2005
Silva, L. V.; Sanguinetti, M.; Vandeputte, P.; Torelli, R.; Rochat, B.; Sanglard, D. Milbemycins: More than Efflux Inhibitors for Fungal Pathogens Antimicrob. Agents Chemother. 2013, 57, 873-886 10.1128/AAC.02040-12
