Landini, G.; Department of Medical Biotechnologies, University of Siena, Siena, Italy
Di Maggio, T.; Department of Medical Biotechnologies, University of Siena, Siena, Italy
Sergio, F.; Corporate Respiratory Medical Affairs, Zambon S.p.A., Bresso, Italy
Docquier, Jean-Denis ; Université de Liège - ULiège > Département des sciences de la vie > Centre d'ingénierie des protéines
Rossolini, G. M.; Department of Medical Biotechnologies, University of Siena, Siena, Italy, Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy, Clinical Microbiology and Virology Unit, Florence Careggi University Hospital, Florence, Italy, Don Carlo Gnocchi Foundation, Florence, Italy
Pallecchi, L.; Department of Medical Biotechnologies, University of Siena, Siena, Italy
Language :
English
Title :
Effect of high N-acetylcysteine concentrations on antibiotic activity against a large collection of respiratory pathogens
Hurst GA, Shaw PB, LeMaistre CA. 1967. Laboratory and clinical evaluation of the mucolytic properties of acetylcysteine. Am Rev Respir Dis 96:962-970.
Rushworth GF, Megson IL. 2014. Existing and potential therapeutic uses for N-acetylcysteine: the need for conversion to intracellular glutathione for antioxidant benefits. Pharmacol Ther 141:150-159. http://dx.doi.org/10.1016/j.pharmthera.2013.09.006.
Samuni Y, Goldstein S, Dean OM, Berk M. 2013. The chemistry and biological activities of N-acetylcysteine. Biochim Biophys Acta 1830:4117-4129. http://dx.doi.org/10.1016/j.bbagen.2013.04.016.
Blasi F, Pave C, Rossolini GM, Pallecchi L, Matera MG, Rogliani P, Cazzola M. 2016. The effect of N-acetylcysteine on biofilms: implications for the treatment of respiratory tract infections. Respir Med 117:190-197. http://dx.doi.org/10.1016/j.rmed.2016.06.015.
Cazzola M, Calzetta L, Page C, Jardim J, Chuchalin AG, Rogliani P, Matera MG. 2015. Influence of N-acetylcysteine on chronic bronchitis or COPD exacerbations: a meta-analysis. Eur Respir Rev 24:451-461. http://dx.doi.org/10.1183/16000617.00002215.
Skov M, Pressler T, Lykkesfeldt J, Poulsen HE, Jensen PØ Johansen HK, Qvist T, Kræmer D, Høiby N, Ciofu O. 2015. The effect of short-term, high-dose oral N-acetylcysteine treatment on oxidative stress markers in cystic fibrosis patients with chronic P. aeruginosa infection - a pilot study. J Cyst Fibros 14:211-218. http://dx.doi.org/10.1016/j.jcf.2014.09.015.
Parry MF, Neu HC. 1977. Effect of N-acetylcysteine on antibiotic activity and bacterial growth in vitro. J Clin Microbiol 5:58-61.
Roberts D, Cole P. 1981. N-Acetylcysteine potentiates the antipseudomonas activity of carbenicillin in vitro. J Infect 3:353-359. http://dx.doi.org/10.1016/S0163-4453(81)91958-7.
Alfredsson H, Malmborg AS, Strandvik B. 1987. N-Acetylcysteine and 2-mercaptoethane sulphonate inhibit anti-pseudomonas activity of antibiotics in vitro. Eur J Respir Dis 70:213-217.
Goswami M, Jawali N. 2010. N-Acetylcysteine-mediated modulation of bacterial antibiotic susceptibility. Antimicrob Agents Chemother 54:3529-3350. http://dx.doi.org/10.1128/AAC.00710-10.
Rodríguez-Beltrán J, Cabot G, Valencia EY, Costas C, Bou G, Oliver A, Blázquez J. 2015. N-Acetylcysteine selectively antagonizes the activity of imipenem in Pseudomonas aeruginosa by an OprD-mediated mechanism. Antimicrob Agents Chemother 59:3246-3251. http://dx.doi.org/10.1128/AAC.00017-15.
Yang F, Liu LH, Li XP, Luo JY, Zhang Z, Yan ZT, Zhang SD, Li HS. 2016. Short communication: N-acetylcysteine-mediated modulation of antibiotic susceptibility of bovine mastitis pathogens. J Dairy Sci 99:4300-4302. http://dx.doi.org/10.3168/jds.2015-10756.
Szkudlarek U, Zdziechowski A, Witkowski K, Kasielski M, Luczyńska M, Luczyński R, Sarniak A, Nowak D. 2004. Effect of inhaled N-acetylcysteine on hydrogen peroxide exhalation in healthy subjects. Pulm Pharmacol Ther 17:155-162. http://dx.doi.org/10.1016/j.pupt.2004.01.007.
Clinical and Laboratory Standards Institute. 2015. Methods for dilution antimicrobial susceptibility tests for bacteria that grow aerobically: approved standard - 10th ed. M07-A10. Clinical and Laboratory Standards Institute, Wayne, PA.
Jones RN, Critchley IA, Whittington WL, Janjic N, Pottumarthy S. 2005. Activity of faropenem tested against Neisseria gonorrhoeae isolates including fluoroquinolone-resistant strains. Diagn Microbiol Infect Dis 53:311-317. http://dx.doi.org/10.1016/j.diagmicrobio.2005.06.014.
Clinical and Laboratory Standards Institute. 1999. Methods for determining bactericidal activity of antimicrobial agents: approved guidelines. M26-A. Clinical and Laboratory Standards Institute, Wayne, PA.
Wu KM, Li LH, Yan JJ, Tsao N, Liao TL, Tsai HC, Fung CP, Chen HJ, Liu YM, Wang JT, Fang CT, Chang SC, Shu HY, Liu TT, Chen YT, Shiau YR, Lauderdale TL, Su IJ, Kirby R, Tsai SF. 2009. Genome sequencing and comparative analysis of Klebsiella pneumoniae NTUH-K2044, a strain causing liver abscess and meningitis. J Bacteriol 191:4492-4501. http://dx.doi.org/10.1128/JB.00315-09.
Stover CK, Pham XQ, Erwin AL, Mizoguchi SD, Warrener P, Hickey MJ, Brinkman FS, Hufnagle WO, Kowalik DJ, Lagrou M, Garber RL, Goltry L, Tolentino E, Westbrock-Wadman S, Yuan Y, Brody LL, Coulter SN, Folger KR, Kas A, Larbig K, Lim R, Smith K, Spencer D, Wong GK, Wu Z, Paulsen IT, Reizer J, Saier MH, Hancock RE, Lory S, Olson MV. 2000. Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic pathogen. Nature 406:959-964. http://dx.doi.org/10.1038/35023079.
Diancourt L, Passet V, Nemec A, Dijkshoorn L, Brisse S. 2010. The population structure of Acinetobacter baumannii: expanding multiresistant clones from an ancestral susceptible genetic pool. PLoS One 5:e10034. http://dx.doi.org/10.1371/journal.pone.0010034.
Landini G, Riccobono E, Giani T, Arena F, Rossolini GM, Pallecchi L. 2015. Bactericidal activity of ceftaroline against mature Staphylococcus aureus biofilms. Int J Antimicrob Agents 45:551-553. http://dx.doi.org/10.1016/j.ijantimicag.2015.01.001.
