Letter to the Editor from Hernan Valdes-Socin: “Genetic Study in a Large Cohort Supported Different Pathogenesis of Graves’ Disease and Hashimoto’s Hypothyroidism”

Zhang et al (JCEM 2020) identified several susceptibility genes of Hashimoto and Graves disease in a Chinese Han population. Conversion of Hashimoto Thyroiditis towards Graves’ disease is still an underestimated clinical feature for most clinicians: susceptibility genes for these cases are still unknown.More extensive cohort immunological and genetic
studies are necessary to gain insight into these interesting observations.