[en] This study reveals the importance of congenital abnormalities during the routine reproductive examination of peripubertal animals, as well as the association of histopathological complementary examination for the research functional and inflammatory anomalies of the uterus. Genetic screening of breeders would be very important in the search for genetic risk factors associated with these congenital pathologies, which can be disseminated by reproductive biotechnologies
Disciplines :
Veterinary medicine & animal health
Author, co-author :
Gherissi, Djallel
Lamraoui, Ramzi
Chacha, Faycal
Bouzebda, Zoubir
Bouzebda, Farida
Hanzen, Christian ; Université de Liège - ULiège > Département clinique des animaux de production (DCP) > Département clinique des animaux de production (DCP)
Language :
English
Title :
Genital abnormalities associated to lack of uterine adenogenesis or endometrial gland dysgenesis of female dromedary camels (Camelus dromedarius)
Publication date :
29 February 2020
Journal title :
Open Veterinary Journal
ISSN :
2226-4485
eISSN :
2218-6050
Publisher :
University of Tripoli. Faculty of Veterinary Medicine, Tripoli, Libya
Ali, A. 2010. Observations on the topography of the reproductive tract of the Arabian female camel. J. Agric. Vet. Sci. Qassim Univ. 3, 33–41.
Ali, A., Derar, R., Al-Sobayil, F., Al-Hawas, F. and Hassanein, K. 2015. A retrospective study on clinical findings of 7300 cases (2007–2014) of barren female dromedaries. Theriogenology. 84, 452–456.
Ali, H.M., Qureshi, A.S., Urbinati, G., Hussain, R., Mustafa, M.Z., Ali, F., Manan, A. and Massaad-Massade, L. 2017. Effects of natural environment on reproductive histo-morphometric dynamics of female dromedary camel. Anim. Reprod. 181, 30–40.
Azawi, O.I. and Ali, A.J. 2011. A study on the prevalence of some pathological abnormalities of the uterus diagnosed at post mortem of buffaloes in Mosul. Buffalo Bull. 30(1), 67–71.
Beena, V., Pawaiya, R.V.S., Shivasharanappa, N., Gururaj, K., Gupta, V.K., Gangwar, N.K., Singh, D.D., Karikalan, M., Sharma, A.K., Kumar, H., Kumar, A. and Singh, R. 2015. Occurrence of pathological conditions in the female genitalia of goats. Indian J. Vet. Pathol. 39(3), 197–201.
Benaissa, M.H., Faye, B. and Kaidi, R. 2015. Reproductive abnormalities in female camel (Camelus dromedarius) in Algeria: relationship with age, season, breed and body condition score. J. Camel Pract. Res. 22(1), 67–73.
Benaissa, M.H., Mimoune, N. and Kaidi, R. 2017. Prevalence and anatomohistopathologic studies of uterine anomalies in she-camels in southeast Algeria. Human Vet. Med. 9(4), 137–145.
Brookshire, W.C., Shivley, J., Woodruff, K. and Cooley, J. 2017. Uterus unicornis and pregnancy in two feline littermates. JFMS Open Rep. 3(2), 2055116917743614.
Carson, S.A., Simpson, J.L., Malinak, L.R., Elias, S., Gerbie, A.B., Buttram, V.C. and Sarto, G.E. 1983. Heritable aspects of uterine anomalies. II. Genetic analysis of Müllerian aplasia. Fertil. Steril. 40(1), 86–90.
Chethan, S.G., Singh, S.K., Karikalan, M., Kharayat, N.S., Behera, B.K., Narayanan, K. and Kumar, H. 2017. Congenital anomalies of the uterus in Riverine buffalo (Bubalus bubalis). Buffalo. Bull. 36(4), 581–587.
Colaço, B., Pires, M.A. and Payan-Carreira, R. 2012. Congenital aplasia of the uterine-vaginal segment in dogs. In A bird’s-eye view of veterinary medicine. Ed., Perez-Marin, C.C. In Tech Open, pp: 165–178. DOI: 10.5772/31419.
Connell, M., Owen, C. and Segars, J. 2013. Genetic syndromes and genes involved in the development of the female reproductive tract: a possible role for gene therapy. J. Genet. Syndr. Gene Ther. 4, 127; doi:10.4172/2157-7412.1000127.
Cooke, P.S., Spencer, T.E., Bartol, F.F. and Hayashi, K. 2013. Uterine glands: development, function and experimental model systems. Mol. Hum. Reprod. 19, 547–558.
Demir, B., Guven, S., Guvendag Guven, E.S. and Gunalp, G.S. 2007. An incidental finding of unicornuate uterus with unilateral ovarian agenesis during cesarean delivery. Arch. Gynecol. Obstet. 276(1), 91–93.
Dhaliwal, G.S., Murray, R.D. and Woldehiwet, Z. 2001. Some aspects of immunology of the bovine uterus related to treatments for endometritis. Anim. Reprod. Sci. 67, 135–152.
Dockweiler, J.C., Cossic, B., Donnelly, C.G., Gilbert, R.O., Buckles, E. and Cheong, S.H. 2017. Infertility associated with the absence of endometrial progesterone receptors in a bitch. Reprod. Domest. Anim. 52(1), 174–178.
El-Wishy, A.B. 1989. Genital abnormalities of the female dromedary (Camelus dromedurius). An abattoir survey. Reprod. Domest. Anim. 24, 84–87.
Emam, M.A. 2014. Immunohistochemical localization of androgen and progesterone receptors in the uterus of the camel (Camelus dromedarius). Acta. Histochem. 116, 1225–1230.
Faye, B. and Esenov, P. 2005. Factors affecting reproductive performance of camels at the herd and individual level. In Desertification combat and food safety: the added value of camel producers. Eds., Tibary, T., Anouassi, A. and Sghiri, A. NATO Science Series, I: Life and Behavioural Sciences, vol. 362, pp. 97–114.
Faye, B.M., Bengoumi, A., Cleradin, A., Tabarani, A. and Chilliard, Y. 2001. Body condition score in dromedary camel: a tool for management of reproduction. In Proceedings of the International Twin Conference on Reproduction/Production in Camelids, Al-Ain, U.A.E. Emir. J. Agric. Sci. 13, 1–6.
Filant, J. and Spencer, T.E. 2014. Uterine glands: biological roles in conceptus implantation, uterine receptivity, and decidualization. Int. J. Dev. Biol. 58, 107–116.
Floyd, J.G., McElhenney, W.H., Heath, A.M., Blaylock, R.E., Norris, B.E., Pegues, M.D., Carson, R.L., Coleman, D.A. and Bartol, F.F. 2001. Fertility of beef heifers treated from birth with growth promoting implants. In ASAS Southern Section Abstracts. 5 (abstract 15).
Gallacher, K. and Gilbert, R.O. 2018. Case report: successful foaling in a Warmblood mare with uterus unicornis. Clin. Theriogenol. 10, 51–58.
Gerstenberg, C., Allen, W.R. and Stewart, F. 1999. Cell proliferation patterns during development of the equine placenta. J. Reprod. Fertil. 117, 143–152.
Gherissi, D.E., Afri-Bouzebda, F. and Bouzebda, Z. 2017. Gestational age estimation of Sahraoui dromedary camel based on fetomaternal measures and phenotypic characteristics. J. Anim. Vet. Adv. 16(2), 32–39.
Gherissi, D.E., Afri-Bouzebda, F. and Bouzebda, Z. 2018a. Seasonal changes in the testicular morphology and interstitial tissue histomorphometry of Sahraoui camel under Algerian extreme arid conditions. Biol. Rhythm Res. 49(2), 1–11.
Gherissi, D.E., Afri-Bouzedba, F., Bouzebda, Z. and Bonnet, X. 2018b. Are female camels capital breeders? Influence of seasons, age, and body condition on reproduction in an extremely arid region. Mamm. Biol. 93, 124–134.
Gherissi, D.E., Bouzebda, Z., Bouzebda Afri, F., Lamraoui, R. and Chacha, F. 2019. Cross-sectional survey of congenital and acquired genital disorders in Sahraoui female camels (Camelus dromedarius) at El Oued abattoir, south-east Algeria. Anim. Res. Int. 16(3), 3450–3462.
Golan, A., Langer, R., Bukovsky, I. and Caspi, E. 1989. Congenital anomalies of the mullerian system. Fertil. Steril. 51(5), 747–755.
Gray, C.A., Bartol, F.F., Taylor, K.M., Wiley, A.A., Ramsey, W.S., Ott, T.L., Bazer, F.W. and Spencer, T.E. 2000. Ovine uterine gland knock-out model: effects of gland ablation on the estrous cycle. Biol. Reprod. 62, 448–456.
Gray, C.A., Burghardt, R.C., Johnson, G.A., Bazer, F.W. and Spencer, T.E. 2002. Evidence that absence of endometrial gland secretions in uterine gland knockout ewes compromises conceptus survival and elongation. Reproduction. 124, 289–300.
Gray, C.A., Taylor, K.M., Ramsey, W.S., Hill, J.R., Bazer, F.W., Bartol, F.F. and Spencer, T.E. 2001b. Endometrial glands are required for preimplantation conceptus elongation and survival. Biol. Reprod. 64(6), 1608–1613.
Hanzen, C. 2015a. Sémiologie: La propédeutique de l’appareil génital femelle des ruminants. Documents pédagogiques: Notes de cours et syllabus. Université de Liège. Available via https://orbi.uliege.be/bitstream/2268/70541/1/R03_ Proped_genitale_femelle_2016.pdf
Hanzen, C. 2015b. L’anoestrus pubertaire et du post-partum dans l’espèce bovine. Documents pédagogiques: Notes de cours et syllabus. Université de Liège. Available via www.therioruminant.ulg. ac.be/notes/200809/R09_Anoestrus_bovin_2009_ PWP.pdf
Hatipoglu, F., Ortatatli, M., Kiran, M.M., Erer, H. and Ciftci, M.K. 2002. An abattoir study of genital pathology in cows:II. Uterus, Cervix and Vagina. Revue. Med. Vet. 152(2), 93–100.
Haydardedeoglu, B., Simsek, E., Kilicdag, E.B., Tarim, E., Aslan, E. and Bagis, T. 2006. A case of unicornuate uterus with ipsilateral ovarian and renal agenesis. Fertil. Steril. 85(3), 750.e1-750.e4.
Jeong, J.W., Kwak, I., Lee, K.Y., Kim, T.H., Large, M.J., Stewart, C.L., Kaestner, K.H., Lydon, J.P. and DeMayo, F.J. 2010. Foxa2 is essential for mouse endometrial gland development and fertility. Biol. Reprod. 83, 396–403.
Jeong, J.W., Lee, H.S., Franco, H.L., Broaddus, R.R., Taketo, M.M., Tsai, S.Y., Lydon, J.P. and DeMayo, F.J. 2009. Beta-catenin mediates glandular formation and dysregulation of beta-catenin induces hyperplasia formation in the murine uterus. Oncogene. 28, 31–40.
Massé, J., Watrin, T., Laurenta, A., Deschamps, S., Guerrier, D. and Pellerin, I. 2009. The developing female genital tract: from genetics to epigenetics. Int. J. Dev. Biol. 53, 411–424.
McIntyre, R.L., Levy, J.K., Roberts, J.F. and Reep, R.L. 2010. Developmental uterine anomalies in cats and dogs undergoing elective ovariohysterectomy. J. Am. Vet. Med. Assoc. 237(5), 542–546.
Melaku, S.K., Melaku, M., Feyisa, A., Demissie, T., Regassa, F., Mekonnen, G.A., Almaw, G., Tessema, T.S., Kassa, T. and Dawo, F. 2015. Pathological and bacteriological study on abnormalities of female internal reproductive organ of Camelus dromedarius slaughtered at Akaki abattoir, Ethiopia. American-Eurasian J. Sci. Res. 10(4), 193–202.
Miller, C. and Sassoon, D.A. 1998. Wnt-7a maintains appropriate uterine patterning during the development of the mouse female reproductive tract. Develop. 125, 3201–3211.
Mimoune, N., Kaidi, R., Azzouz, M.Y., Keddour, R., Belarbi, A. and Derdour, S.Y. 2016. Genital tract pathologies of cows slaughtered at El-Harrach abattoir in Algeria. Kafkas Univ. Vet. Fak. Derg. 22(5), 639–646.
Moriyama, C., Kobayashi, I., Tani, M., Oishi, T., Kajisa, M., Horii, Y. and Kamimura, S. 2008. Case of pregnancy in two cows with unicorn horn of the uterus either by artificial insemination at ipsilateral or embryo transfer at contralateral Corpus luteum in the Ovary. Reprod. Domest. Anim. 43(3), 382–384.
Mülayim, B., Demirbasoglu, S. and Oral, O. 2003. Unicornuate uterus and unilateral ovarian agenesis associated with pelvic kidney. Surg. Endosc. 17(1), 161.
Oh, K.S., Son, C.H., Kim, B.S., Hwang, S.S., Kim, Y.J., Park, S.J., Jeong, J.H., Jeong, C., Park, S.H. and Cho, K.O. 2005. Segmental aplasia of uterine body in an adult mixed breed dog. J. Vet. Diagn. Invest. 17, 490–492.
Osman, A.K., Abbott, L.C. and Ahmed, A.A.M. 2018. Survey of nuclear progesterone receptor expression in the uterus of the cyclic and pregnant camel (Camelus dromedarius). Anat. Histol. Embryol. 47(6), 544–550.
Rendel, J.M. 1952. White heifer disease in a herd of dairy Shorthorn. J. Genet. 51(1), 89–94.
Ribadu, A.Y., Ogwu, D., Njokut, C.O. and Eduviet, L.O. 1991. Abattoir survey of female genital disorders of imported camels (Camelus dromedarius) in Kano, Nigeria. Br. Vet. J. 147(2), 90.
Roberts, S.J. 1971. Infertility the cow: veterinary obstetrics and genital diseases, 2nd Ed. Ithaca, New York, pp. 464–465.
Shawky, A.M., Tantawy, A.A. and Ibrahim, M.F. 2004. An abattoir survey of female genital disorders of camels (Camelus dromedaries) in Kalyoubia, Egypt. 1st Annual Conference, FVM., Moshtohor, Sept, 2004.
Shulman, L.P. and Elias, S. 1988. Developmental abnormalities of the female reproductive tract: pathogenesis and nosology. Acta Obstet. Gynecol. Scand. 67, 441.
Smith, K.C., Long, S.E. and Parkinson, T.J. 1995. Congenital abnormalities of the ovine paramesonephric ducts. Br. Vet. J. 151, 443–451.
Smith, T.I.M. 1985. Reproduction in South American Camelids. Iowa State Univ. Vet. 47(2), 6. Available via https://lib.dr.iastate.edu/iowastate_veterinarian/vol47/iss2/6
Spencer, T.E., Kelleher, A.M. and Bartol, F.F. 2019. Development and Function of Uterine Glands in Domestic Animals. Annu. Rev. Anim. Biosci. 7, 125–147.
Tibary, A. 2007. Breeding soundness evaluation and subfertility in female llamas and alpacas. In: Youngquist R., Threlfall W., eds. Current therapy in large animal theriogenology. 2nd ed., Saunders/ Elsevier, St. Louis, MO, pp. 878–883.
Tibary, A. and Anouassi, A. 1997. Theriogenology in camelidae. anatomy, physiology, pathology and artificial breeding. 1st ed., Abu Dhabi Printing and Publishin Company, Mina, Abu Dhabi, UAE.
Tibary, A., Anouassi, A. and Memon, M.A. 2001. Approach to diagnosis of infertility in camelids: retrospective study in alpaca, lamas and camels. J. Camel Pract. Res. 8, 167–179.
Verp, M.S., Simpson, J.L., Elias, S., Carson, S.A., Sarto, G.E. and Feingold, M. 1983. Heritable aspects of uterine anomalies. I. Three familial aggregates with Müllerian fusion anomalies. Fertil. Steril. 40(1), 80–85.
Wajid, S.J. 2015. A pathological abattoir survey of the reproductive tracts of non pregnant camels (Camelus dromedaries) in Iraq. IOSR J. Pharm. Biol. Sci. 10, 84–90.
Warot, X., Fromental-Ramain, C., Fraulob, V., Chambon, P. and Dollé, P. 1997. Gene dosage-dependent effects of the Hoxa-13 and Hoxd-13 mutations on morphogenesis of the terminal parts ofthe digestive and urogenital tracts. Develop. 124, 4781–4791.
Witkowski, M., Katkiewicz, M., Kochan, J. and Panzani, D. 2017. Uterine glands agenesia in the mare. J. Equine Vet. Sci. 58, 47–50.
