Article (Scientific journals)
Screening of cytotoxic activities of Strychnos alkaloids ( methods and results)
Quetin-Leclercq, Joëlle; De Pauw-Gillet, Marie-Claire; Bassleer, Roger et al.
1986In Journal of Ethnopharmacology, 15, p. 305-316
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Keywords :
cytotoxic activities; cancer cells; normal cells; Indole alkaloids; Strychnos species
Abstract :
[en] The potential cytotoxic activities of 46 alkaloids isolated from different Strychnos species were tested on different cancer or normal cells cultured in vitro. The authors use a relatively simple microtest which gives good reproducibility. Most of the active compounds belong to the usambarane skeleton but other structure-activity relationships are being discussed.
Disciplines :
Pharmacy, pharmacology & toxicology
Author, co-author :
Quetin-Leclercq, Joëlle 
De Pauw-Gillet, Marie-Claire ;  Université de Liège - ULiège > Département des sciences biomédicales et précliniques > Histologie - Cytologie - Département des sciences biomédicales et précliniques
Bassleer, Roger ;  Université de Liège - ULiège > Relations académiques et scientifiques (Médecine)
Angenot, Luc  ;  Université de Liège - ULiège > Département de pharmacie > Pharmacognosie
Language :
English
Title :
Screening of cytotoxic activities of Strychnos alkaloids ( methods and results)
Publication date :
1986
Journal title :
Journal of Ethnopharmacology
ISSN :
0378-8741
eISSN :
1872-7573
Publisher :
Elsevier Sequoia, Limerick, Ireland
Volume :
15
Pages :
305-316
Peer reviewed :
Peer Reviewed verified by ORBi
Available on ORBi :
since 10 May 2010

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