Intense sport practices and cardiac biomarkers

[en] Biomarkers are well established for the diagnosis of myocardial infarction, heart failure and cardiac fibrosis. Different papers on cardiac biomarker evolution during exercise have been published in the literature and generally show mild to moderate elevations. However, the mechanism responsible for these elevations, reflecting physiological or even pathophysiological changes, still has to be clearly elucidated. There are also indications of higher cardiac risk in poorly trained athletes than in well-trained athletes. Whether regular repetition of intensive exercise might lead, in the longer term, to fibrosis and heart failure remains to be determined. In this review, we summarized the main research about the effects of intense exercise (in particular, running) on cardiac biomarkers (including troponins, natriuretic peptides, etc.). We found that cardiac fibrosis biomarkers seemed to be the most informative regarding the biological impact of intense physical activity.

Disciplines :

Orthopedics, rehabilitation & sports medicine

Author, co-author :

LE GOFF, Caroline ; Centre Hospitalier Universitaire de Liège - CHU > Unilab > Laboratoire techniques séparatives et stress oxydant

Farre Segura, Jordi ; Université de Liège - ULiège > Département de pharmacie > Chimie médicale

Dufour, Patrice ; Centre Hospitalier Universitaire de Liège - CHU > Unilab > Pool assistant - biologie clinique

KAUX, Jean-François ; Centre Hospitalier Universitaire de Liège - CHU > Autres Services Médicaux > Service de médecine de l'appareil locomoteur

CAVALIER, Etienne ; Centre Hospitalier Universitaire de Liège - CHU > Unilab > Service de chimie clinique

Language :

English

Title :

Intense sport practices and cardiac biomarkers

Publication date :

May 2020

Journal title :

Clinical Biochemistry

ISSN :

0009-9120

eISSN :

1873-2933

Publisher :

Elsevier, Netherlands

Volume :

Pages :

1-8

Peer reviewed :

Peer Reviewed verified by ORBi

Available on ORBi :

since 03 March 2020

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