Article (Scientific journals)
Strategies to reduce curative antibiotic therapy in intensive care units (adult and paediatric).
Bretonniere, Cedric; Leone, Marc; Milesi, Christophe et al.
2015In Intensive Care Medicine, 41 (7), p. 1181-96
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Keywords :
Anti-Bacterial Agents/therapeutic use; Bacterial Infections/diagnosis/drug therapy; Critical Care; Cross Infection/drug therapy; Drug Monitoring; Drug Resistance, Microbial; Humans; Intensive Care Units; Intensive Care Units, Pediatric; Unnecessary Procedures
Abstract :
[en] Emerging resistance to antibiotics shows no signs of decline. At the same time, few new antibacterials are being discovered. There is a worldwide recognition regarding the danger of this situation. The urgency of the situation and the conviction that practices should change led the Societe de Reanimation de Langue Francaise (SRLF) and the Societe Francaise d'Anesthesie et de Reanimation (SFAR) to set up a panel of experts from various disciplines. These experts met for the first time at the end of 2012 and have since met regularly to issue the following 67 recommendations, according to the rigorous GRADE methodology. Five fields were explored: i) the link between the resistance of bacteria and the use of antibiotics in intensive care; ii) which microbiological data and how to use them to reduce antibiotic consumption; iii) how should antibiotic therapy be chosen to limit consumption of antibiotics; iv) how can antibiotic administration be optimized; v) review and duration of antibiotic treatments. In each institution, the appropriation of these recommendations should arouse multidisciplinary discussions resulting in better knowledge of local epidemiology, rate of antibiotic use, and finally protocols for improving the stewardship of antibiotics. These efforts should contribute to limit the emergence of resistant bacteria.
Disciplines :
Anesthesia & intensive care
Author, co-author :
Bretonniere, Cedric
Leone, Marc
Milesi, Christophe
Allaouchiche, Bernard
Armand-Lefevre, Laurence
Baldesi, Olivier
Bouadma, Lila
Decre, Dominique
Figueiredo, Samy
Gauzit, Remy
Guery, Benoit
Joram, Nicolas
Jung, Boris
Lasocki, Sigismond
Lepape, Alain
Lesage, Fabrice
Pajot, Olivier
Philippart, Francois
Souweine, Bertrand
Tattevin, Pierre
Timsit, Jean-Francois
Vialet, Renaud
Zahar, Jean Ralph
Misset, Benoît ;  Centre Hospitalier Universitaire de Liège - CHU > Service de Soins Intensifs
Bedos, Jean-Pierre
More authors (15 more) Less
Language :
English
Title :
Strategies to reduce curative antibiotic therapy in intensive care units (adult and paediatric).
Publication date :
2015
Journal title :
Intensive Care Medicine
ISSN :
0342-4642
eISSN :
1432-1238
Publisher :
Springer, Heidelberg, Germany
Volume :
41
Issue :
7
Pages :
1181-96
Peer reviewed :
Peer Reviewed verified by ORBi
Available on ORBi :
since 21 February 2020

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