Article (Scientific journals)
A Consensus on the Diagnosis and Treatment of Acromegaly Comorbidities: An Update.
Giustina, Andrea; Barkan, Ariel; Beckers, Albert et al.
2019In Journal of Clinical Endocrinology and Metabolism
 

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Keywords :
acromegaly; comorbidities; consensus; diagnosis; treatment
Abstract :
[en] OBJECTIVE: The aim of the Acromegaly Consensus Group was to revise and update the consensus on diagnosis and treatment of acromegaly comorbidities last published in 2013. PARTICIPANTS: The Consensus Group, convened by 11 Steering Committee members, consisted of 45 experts in the medical and surgical management of acromegaly. The authors received no corporate funding or remuneration. EVIDENCE: This evidence-based Consensus was developed using the Grading of Recommendations, Assessment, Development, and Evaluation (GRADE) system to describe both the strength of recommendations and the quality of evidence following critical discussion of the current literature on the diagnosis and treatment of acromegaly comorbidities. CONSENSUS PROCESS: Acromegaly Consensus Group participants conducted comprehensive literature searches for English-language papers on selected topics, reviewed brief presentations on each topic, and discussed current practice and recommendations in breakout groups. Consensus recommendations were developed based on all presentations and discussions. Members of the Scientific Committee graded the quality of the supporting evidence and the consensus recommendations using the GRADE system. CONCLUSIONS: Evidence-based approach consensus recommendations address important clinical issues regarding multidisciplinary management of acromegaly-related cardiovascular, endocrine, metabolic, and oncologic comorbidities, sleep apnea, and bone and joint disorders and their sequelae, as well as their effects on quality of life and mortality.
Disciplines :
Endocrinology, metabolism & nutrition
Author, co-author :
Giustina, Andrea
Barkan, Ariel
Beckers, Albert ;  Université de Liège - ULiège > Département des sciences cliniques > Endocrinologie
Biermasz, Nienke
Biller, Beverly M. K.
Boguszewski, Cesar
Bolanowski, Marek
Bonert, Vivien
Bronstein, Marcello D.
Casanueva, Felipe F.
Clemmons, David
Colao, Annamaria
Ferone, Diego
Fleseriu, Maria
Frara, Stefano
Gadelha, Monica R.
Ghigo, Ezio
Gurnell, Mark
Heaney, Anthony P.
Ho, Ken
Ioachimescu, Adriana
Katznelson, Laurence
Kelestimur, Fahrettin
Kopchick, John
Krsek, Michal
Lamberts, Steven
Losa, Marco
Luger, Anton
Maffei, Pietro
Marazuela, Monica
Mazziotti, Gherardo
Mercado, Moises
Mortini, Pietro
Neggers, Sebastian
Pereira, Alberto M.
Petersenn, Stephan
Puig-Domingo, Manel
Salvatori, Roberto
Shimon, Ilan
Strasburger, Christian
Tsagarakis, Stylianos
van der Lely, A. J.
Wass, John
Zatelli, Maria Chiara
Melmed, Shlomo
More authors (35 more) Less
Language :
English
Title :
A Consensus on the Diagnosis and Treatment of Acromegaly Comorbidities: An Update.
Publication date :
2019
Journal title :
Journal of Clinical Endocrinology and Metabolism
ISSN :
0021-972X
eISSN :
1945-7197
Publisher :
Oxford University Press, New York, United States - New York
Commentary :
(c) Endocrine Society 2019. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.
Available on ORBi :
since 28 January 2020

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