Relationship between the changes over time of bone mass and muscle health in children and adults: A systematic review and meta-analysis

Locquet, Médéa; Beaudart, Charlotte; Durieux, Nancy; Reginster, Jean-Yves; Bruyère, Olivier

doi:10.1186/s12891-019-2752-4

Article (Scientific journals)

Relationship between the changes over time of bone mass and muscle health in children and adults: A systematic review and meta-analysis

Locquet, Médéa; Beaudart, Charlotte; Durieux, Nancy et al.

2019 • In BMC Musculoskeletal Disorders, 20, p. 429

Peer Reviewed verified by ORBi

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https://hdl.handle.net/2268/241242

DOI
10.1186/s12891-019-2752-4

PubMed
31521141

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Keywords :

Bone mineral density; Longitudinal; Meta-analysis; Muscle-bone unit; Musculoskeletal health; Review

Abstract :

[en] Background: Various cross-sectional studies provide an abundance of evidence that shows a relationship between bone quantity and muscle health. However, one question remains, less-often studied: is their development - or decline - associated? The aim of the research was to conduct a systematic review and meta-analysis to summarize the studies exploring the association between changes in bone mineral density (BMD) and changes in muscle parameters (registration CRD42018093813). Methods: We searched for prospective studies, both in children and adults, by consulting electronic databases (Ovid-MEDLINE, Ovid-AMED, Scopus). Each review steps were performed by two independent reviewers. For outcomes reported by less of 3 studies, we synthetized the results narratively. In other cases, a meta-analysis was performed, giving an overall r coefficient and its 95% confidence interval (CI). Results: Fifteen papers were included. In connection with the change of BMD, 10 studies concerned the parallel change of lean mass, 4 were about grip strength, and 1 was about physical performance. Children were the population of interest for 5 studies, while the aging population was the focus of the other studies. The correlation between hip BMD and lean mass was significant, with an overall coefficient r = 0.37 (95% CI 0.23-0.49). High heterogeneity was observed between studies but the length of follow-up, sex and study quality did not seem to significantly influence results. The systematic review allowed some other highlights: a significant link between changes in BMD and changes in muscle strength was observed (p-value < 0.05 in the 4 studies), in addition to changes in performance (1 study, r = 0.21, p-value = 0.004). Conclusion: Despite the heterogeneity between studies, we highlighted a significant association between the change of BMD and the change of various muscle parameters. Future studies should investigate preventive and therapeutic strategies that are based on a single entity: the 'muscle-bone unit'. © 2019 The Author(s).

Disciplines :

Public health, health care sciences & services

Author, co-author :

Locquet, Médéa ; Université de Liège - ULiège > Département des sciences de la santé publique > Epidémiologie clinique

Beaudart, Charlotte ; Université de Liège - ULiège > Département des sciences de la santé publique > Santé publique, Epidémiologie et Economie de la santé

Durieux, Nancy ; Université de Liège - ULiège > Bibliothèque des Sciences de la vie

Reginster, Jean-Yves ; Université de Liège - ULiège > Département des sciences de la santé publique > Santé publique, Epidémiologie et Economie de la santé

Bruyère, Olivier ; Université de Liège - ULiège > Département des sciences de la santé publique > Santé publique, Epidémiologie et Economie de la santé

Language :

English

Title :

Relationship between the changes over time of bone mass and muscle health in children and adults: A systematic review and meta-analysis

Publication date :

2019

Journal title :

BMC Musculoskeletal Disorders

eISSN :

1471-2474

Publisher :

BioMed Central Ltd.

Volume :

Pages :

429

Peer reviewed :

Peer Reviewed verified by ORBi

Available on ORBi :

since 13 November 2019

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Bibliography

Kamper SJ, Henschke N, Hestbaek L, Dunn KM, Williams CM. Musculoskeletal pain in children and adolescents. Brazilian J Phys Ther. 2016;20:275-84. https://doi.org/10.1590/bjpt-rbf.2014.0149.
Sudhagoni RG, Wey HE, Djira GD, Specker BL. Longitudinal effects of fat and lean mass on bone accrual in infants. Bone. 2012;50:638-42. https://doi.org/10.1016/j.bone.2011.11.011.
Roux CH, Guillemin F, Boini S, Longuetaud F, Arnault N, Hercberg S, et al. Impact of musculoskeletal disorders on quality of life: an inception cohort study. Ann Rheum Dis. 2005;64:606-11. https://doi.org/10.1136/ard.2004.020784.
Taaffe DR, Marcus R. Musculoskeletal health and the older adult. J Rehabil Res Dev. 37:245-54 http://www.ncbi.nlm.nih.gov/pubmed/10850831. Accessed 18 Aug 2018.
Beaudart C, Zaaria M, Pasleau F, Reginster J-Y, Bruyère O. Health outcomes of sarcopenia: a systematic review and meta-analysis. PLoS One. 2017;12:e0169548. https://doi.org/10.1371/journal.pone.0169548.
Locquet M, Beaudart C, Hajaoui M, Petermans J, Reginster J-Y, Bruyère O. Three-year adverse health consequences of sarcopenia in community-dwelling older adults according to 5 diagnosis definitions. J Am Med Dir Assoc. 2018. https://doi.org/10.1016/j.jamda.2018.06.004.
Cooper C. The crippling consequences of fractures and their impact on quality of life. Am J Med. 1997;103:S12-9. https://doi.org/10.1016/S0002-9343(97)90022-X.
Reginster J-Y, Burlet N. Osteoporosis: a still increasing prevalence. Bone. 2006;38:4-9. https://doi.org/10.1016/j.bone.2005.11.024.
Beaudart C, Locquet M, Reginster J-Y, Delandsheere L, Petermans J, Bruyère O. Quality of life in sarcopenia measured with the SarQoL®: impact of the use of different diagnosis definitions. Aging Clin Exp Res. 2017;30:307-13.
Blasimme A. Physical frailty, sarcopenia, and the enablement of autonomy: philosophical issues in geriatric medicine. Aging Clin Exp Res. 2017;29:59-63. https://doi.org/10.1007/s40520-016-0714-3.
Frost HM. Bone's mechanostat: a 2003 update. Anat Rec. 2003;275A:1081-101. https://doi.org/10.1002/ar.a.10119.
Schoenau E. From mechanostat theory to development of the "Functional Muscle-Bone-Unit". J Musculoskelet Neuronal Interact. 5:232-8 http://www.ncbi.nlm.nih.gov/pubmed/16172514. Accessed 13 Sept 2018.
Schoenau E, Fricke O. Mechanical influences on bone development in children. Eur J Endocrinol. 2008;159 suppl-1:S27-31. https://doi.org/10.1530/EJE-08-0312.
Ho-Pham LT, Nguyen UDT, Nguyen TV. Association between lean mass, fat mass, and bone mineral density: a meta-analysis. J Clin Endocrinol Metab. 2014;99:30-8. https://doi.org/10.1210/jc.2013-3190.
Marin RV, Pedrosa MAC, Moreira-Pfrimer LDF, Matsudo SMM, Lazaretti-Castro M. Association between lean mass and handgrip strength with bone mineral density in physically active postmenopausal women. J Clin Densitom. 2010;13:96-101. https://doi.org/10.1016/j.jocd.2009.12.001.
Kritz-Silverstein D, Barrett-Connor E. Grip strength and bone mineral density in older women. J Bone Miner Res. 2009;9:45-51. https://doi.org/10.1002/jbmr.5650090107.
Ozgocmen S, Karaoglan B, Cimen OB, Yorgancioglu ZR. Relation between grip strength and hand bone mineral density in healthy women aged 30-70. Singap Med J. 2000;41:268-70 http://www.ncbi.nlm.nih.gov/pubmed/11109342. Accessed 18 Aug 2018.
Lindsey C, Brownbill RA, Bohannon RA, Ilich JZ. Association of Physical Performance Measures with Bone Mineral Density in postmenopausal women. Arch Phys Med Rehabil. 2005;86:1102-7. https://doi.org/10.1016/j.apmr.2004.09.028.
Khazzani H, Allali F, Bennani L, Ichchou L, El Mansouri L, Abourazzak FE, et al. The relationship between physical performance measures, bone mineral density, falls, and the risk of peripheral fracture: a cross-sectional analysis. BMC Public Health. 2009;9:297. https://doi.org/10.1186/1471-2458-9-297.
El Khoury C, Pinti A, Lespessailles E, Maalouf G, Watelain E, El Khoury G, et al. Physical performance variables and bone mineral density in a Group of Young Overweight and Obese men. J Clin Densitom. 2018;21:41-7. https://doi.org/10.1016/j.jocd.2016.07.004.
Moher D, Liberati A, Tetzlaff J, Altman DG, PRISMA Group. Preferred Reporting Items for Systematic Reviews and Meta-Analyses: The PRISMA Statement. PLoS Med. 2009;6:e1000097. https://doi.org/10.1371/journal.pmed.1000097.
Liu-Ambrose T, Kravetsky L, Bailey D, Sherar L, Mundt C, Baxter-Jones A, et al. Change in lean body mass is a major determinant of change in areal bone mineral density of the proximal femur: a 12-year observational study. Calcif Tissue Int. 2006;79:145-51.
Peterson RA, Brown SP. On the use of Beta coefficients in meta-analysis. J Appl Psychol. 2005;90:175-81. https://doi.org/10.1037/0021-9010.90.1.175.
Higgins JPT, Thompson SG, Deeks JJ, Altman DG. Measuring inconsistency in meta-analyses. BMJ. 2003;327:557-60. https://doi.org/10.1136/bmj.327.7414.557.
Young D, Hopper JL, Macinnis RJ, Nowson CA, Hoang NH, Wark JD. Changes in body composition as determinants of longitudinal changes in bone mineral measures in 8 to 26-year-old female twins. Osteoporos Int. 2001;12:506-15.
Wang Q, Alén M, Nicholson P, Suominen H, Koistinen A, Kröger H, et al. Weight-bearing, muscle loading and bone mineral accrual in pubertal girls - a 2-year longitudinal study. Bone. 2007;40:1196-202. https://doi.org/10.1016/j.bone.2006.12.054.
Vicente-Rodriguez G, Ara I, Perez-Gomez J, Dorado C, Calbet JAL. Muscular development and physical activity as major determinants of femoral bone mass acquisition during growth. Br J Sports Med. 2005;39:611-6.
Sirola J, Rikkonen T, Tuppurainen M, Honkanen R, Jurvelin JS, Kröger H. Maintenance of muscle strength may counteract weight-loss-related postmenopausal bone loss - a population-based approach. Osteoporos Int. 2006;17:775-82.
Sirola J, Rikkonen T, Tuppurainen M, Jurvelin JS, Kröger H. Association of grip strength change with menopausal bone loss and related fractures: a population-based follow-up study. Calcif Tissue Int. 2006;78:218-26.
Milliken LA, Cussler E, Zeller RA, Choi JE, Metcalfe L, Going SB, et al. Changes in soft tissue composition are the primary predictors of 4-year bone mineral density changes in postmenopausal women. Osteoporos Int. 2009;20:347-54.
Kwon J, Suzuki T, Yoshida H, Kim H, Yoshida Y, Iwasa H, et al. Association between change in bone mineral density and decline in usual walking speed in elderly community-dwelling Japanese women during 2 years of follow-up. J Am Geriatr Soc. 2007;55:240-4.
Hrafnkelsson H, Sigurdsson G, Magnusson KT, Sigurdsson EL, Johannsson E. Fat mass increase in 7-year-old children: more bone area but lower bone mineral density. J Bone Miner Metab. 2013;31:442-8.
Heidemann M, Holst R, Schou AJ, Klakk H, Husby S, Wedderkopp N, et al. The influence of anthropometry and body composition on Children's bone health: the childhood health, activity and motor performance school (the CHAMPS) study. Denmark Calcif Tissue Int. 2014;96:97-104.
Chen Z, Lohman TG, Stini WA, Ritenbaugh C, Aickin M. Fat or lean tissue mass: which one is the major determinant of bone mineral mass in healthy postmenopausal women? J Bone Min Res. 1997;12:144-51. https://doi.org/10.1359/jbmr.1997.12.1.144.
Cadogan J, Blumsohn A, Barker ME, Eastell R. A longitudinal study of bone gain in pubertal girls: anthropometric and biochemical correlates. J Bone Miner Res. 1998;13:1602-12.
Bleicher K, Cumming RG, Naganathan V, Travison TG, Sambrook PN, Blyth FM, et al. The role of fat and lean mass in bone loss in older men: findings from the CHAMP study. Bone. 2011;49:1299-305. https://doi.org/10.1016/j.bone.2011.08.026.
Arabi A, Baddoura R, El-Rassi R, El-Hajj FG. PTH level but not 25 (OH) vitamin D level predicts bone loss rates in the elderly. Osteoporos Int. 2012;23:971-80.
Sirola J, Tuppurainen M, Honkanen R, Jurvelin JS, Kröger H. Associations between grip strength change and axial postmenopausal bone loss - a 10-year population-based follow-up study. Osteoporos Int. 2005;16:1841-8. https://doi.org/10.1007/s00198-005-1944-y.
Yanf S, Center JR, Eisman JA, Nguyen TV. Association between fat mass, lean mass, and bone loss: the Dubbo Osteoporosis Epidemiology Study. Osteoporos Int. 2015;26(4):1381-6. https://www.ncbi.nlm.nih.gov/pubmed/25572048.
Ho-Pham LT, Nguyen UDT, Nguyen TV. Association between lean mass, fat mass, and bone mineral density: a meta-analysis. J Clin Endocrinol Metabol. 2014;99:30-8. https://academic.oup.com/jcem/article/99/1/30/2836155.
Rajaei A, Dehghan P, Ariannia S, Ahmadzadeh A, Shakiba M, Sheibani K. Correlating whole-body bone mineral densitometry measurements to those from local anatomical sites. Iran J Radiol. 2016;13:e25609. https://doi.org/10.5812/iranjradiol.25609.
Kashyap L, Perera S, Fisher AL. Identification of novel genes involved in sarcopenia through RNAi screening in Caenorhabditis elegans. J Gerontol A Biol Sci Med Sci. 2012;67:56-65. https://doi.org/10.1093/gerona/glr072.
Marini F, Brandi ML. Genetic determinants of osteoporosis: common bases to cardiovascular diseases? Int J Hypertens. 2010;2010. https://doi.org/10.4061/2010/394579.
Cianferotti L, Brandi ML. Muscle-bone interactions: basic and clinical aspects. Endocrine. 2014;45:165-77. https://doi.org/10.1007/s12020-013-0026-8.
Avin KG, Bloomfield SA, Gross S, Warden SJ. Biomechanical aspects of the muscle-bone interaction. Curr Osteoporos Rep. 2015;13(1):1-8. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4306629/.
Shin H, Panton LB, Dutton GR, Ilich JZ. Relationship of physical performance with body composition and bone mineral density in individuals over 60 years of age: a systematic review. SAGE-Hindawi Access to Res J Aging Res. 2011;14. https://doi.org/10.4061/2011/191896.
Curtis E, Litwic A, Cooper C, Dennison E. Determinants of muscle and bone aging. J Cell Physiol. 2015;230:2618-25. https://doi.org/10.1002/jcp.25001.