Expression of Galectins in Cancer: A Critical Review

[en] A large body of literature has examined and described galectin expression in cancer. Discrepancies have been observed in the reported data, which hampered clear understanding of the expression profiles. This relates to the use of different types of methods that evaluate either global or specific gene expression in heterogeneous cancer tissue samples, type of antibodies used in immunohistochemistry and procedures of comparison of gene expression. In this manuscript, we review the main data concerning expression of galectins in human cancer. Only galectin-1 and galectin-3, the most abundant and examined galectins, will be examined here.

Disciplines :

Oncology
Biochemistry, biophysics & molecular biology

Author, co-author :

van den Brule, Frédéric; Université de Liège - ULiège > Laboratoire de Recherche sur les métastases

Califice, Stéphane; Université de Liège - ULiège > Laboratoire de Recherche sur les Métastases

Castronovo, Vincenzo ; Université de Liège - ULiège > Département des sciences biomédicales et précliniques > Biologie générale et cellulaire - GIGA-R : Labo de recherche sur les métastases

Language :

English

Title :

Expression of Galectins in Cancer: A Critical Review

Publication date :

2004

Journal title :

Glycoconjugate Journal

ISSN :

0282-0080

eISSN :

1573-4986

Publisher :

Kluwer Academic Publishers, Netherlands

Volume :

Issue :

7-9

Pages :

537-42

Peer reviewed :

Peer Reviewed verified by ORBi

Funders :

F.R.S.-FNRS - Fonds de la Recherche Scientifique [BE]
Fonds Léon Fredericq [BE]

Available on ORBi :

since 28 September 2009

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Scopus citations^®

173

Scopus citations^®
without self-citations

172

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126

OpenAlex citations

194

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