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Lymphatic and blood systems: Identical or fraternal twins?

Morfoisse, Florent; Noël, Agnès

2019 • In International Journal of Biochemistry and Cell Biology, 114, p. 105562

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https://hdl.handle.net/2268/239129

DOI
10.1016/j.biocel.2019.105562

PubMed
31278994

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Keywords :

Angiogenesis; Endothelium; Lymphangiogenesis; Signalling; VEGFR dimerization

Abstract :

[en] Blood and lymphatic systems work in close collaboration to ensure their respective physiological functions. The lymphatic vessel network is being extensively studied, but has been overlooked as compared to the blood vasculature mainly due to the problematic discrimination of lymphatic vessels from the blood ones. This issue has been fortunately resolved in the past decade leading to the emergence of a huge amount of data in lymphatic biology revealing many shared features with the blood vasculature. However, this likeliness between the two vascular systems may lead to a simplistic view of lymphatics and a direct transcription of what is known for the blood system to the lymphatic one, thereby neglecting the lymphatic specificities. In this context, this review aims to clarify the main differences between the two vascular systems focusing on recently discovered lymphatic features.

Disciplines :

Biochemistry, biophysics & molecular biology

Author, co-author :

Morfoisse, Florent ; Université de Liège - ULiège > Cancer-Tumours and development biology

Noël, Agnès ; Université de Liège - ULiège > Département des sciences cliniques > Labo de biologie des tumeurs et du développement

Language :

English

Title :

Lymphatic and blood systems: Identical or fraternal twins?

Publication date :

2019

Journal title :

International Journal of Biochemistry and Cell Biology

ISSN :

1357-2725

eISSN :

1878-5875

Publisher :

Elsevier, Oxford, United Kingdom

Volume :

114

Pages :

105562

Peer reviewed :

Peer Reviewed verified by ORBi

Commentary :

Copyright (c) 2019 Elsevier Ltd. All rights reserved.

Available on ORBi :

since 03 September 2019

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3 (3 by ULiège)

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